Key Insights

Highlights

Success Rate

78% trial completion

Published Results

199 trials with published results (34%)

Research Maturity

309 completed trials (52% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

14.7%

87 terminated out of 590 trials

Success Rate

78.0%

-8.5% vs benchmark

Late-Stage Pipeline

7%

42 trials in Phase 3/4

Results Transparency

64%

199 of 309 completed with results

Key Signals

199 with results78% success87 terminated

Data Visualizations

Phase Distribution

534Total
Not Applicable (28)
Early P 1 (3)
P 1 (213)
P 2 (248)
P 3 (34)
P 4 (8)

Trial Status

Completed309
Terminated87
Recruiting64
Unknown50
Active Not Recruiting47
Withdrawn18

Trial Success Rate

78.0%

Benchmark: 86.5%

Based on 309 completed trials

Clinical Trials (590)

Showing 20 of 20 trials
NCT06034470Phase 1Active Not Recruiting

Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms

NCT07573111Phase 1Not Yet Recruiting

Open-label, Single Ascending Dose Study of QUAIL-100 in Pediatric and Young Adult Participants With High-Risk Hematologic Malignancies Who Have Received a Hematopoietic Stem Cell Transplantation

NCT05564390Phase 2Recruiting

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

NCT04726241Phase 1Recruiting

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

NCT02727803Phase 2Recruiting

Personalized NK Cell Therapy in CBT

NCT04493138Phase 1Active Not Recruiting

Azacitidine and Quizartinib for the Treatment of Myelodysplastic Syndrome or Myelodysplastic/Myeloproliferative Neoplasm With FLT3 or CBL Mutations

NCT00843882Phase 3Active Not Recruiting

Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia

NCT01231412Phase 3Completed

Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant

NCT01522976Phase 2Active Not Recruiting

Azacitidine With or Without Lenalidomide or Vorinostat in Treating Patients With Higher-Risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia

NCT06195891Phase 1Recruiting

Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome

NCT07249476Not Yet Recruiting

Study of NK Cells in the Monitoring of Patients With Acute Leukemia or Myelodysplasia

NCT06577441Phase 2RecruitingPrimary

Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

NCT06484062Phase 1Recruiting

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

NCT06781099Not ApplicableRecruitingPrimary

Feasibility Trial of Extracorporeal Iron Purification in Patients With Myelodysplastic Syndrome or Myelofibrosis

NCT05969860Phase 2Recruiting

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

NCT07052006Phase 2Active Not RecruitingPrimary

A Phase 2a Study of HT-6184 in Subjects With IPSS-R Very Low, Low or Intermediate Risk MDS and Anemia

NCT02250937Phase 2Active Not Recruiting

Venetoclax and Sequential Busulfan, Cladribine, and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome

NCT01624805Phase 2Recruiting

Methylprednisolone, Horse Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, and/or Pegfilgrastim or Pegfilgrastim Biosimilar in Treating Patients With Aplastic Anemia or Low or Intermediate-Risk Myelodysplastic Syndrome

NCT03192397Phase 1Active Not Recruiting

Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant

NCT00900198Recruiting

Collection of Tissue Samples for Cancer Research

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