Key Insights

Highlights

Success Rate

78% trial completion

Published Results

201 trials with published results (34%)

Research Maturity

312 completed trials (52% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

14.8%

88 terminated out of 596 trials

Success Rate

78.0%

-8.6% vs benchmark

Late-Stage Pipeline

7%

42 trials in Phase 3/4

Results Transparency

64%

201 of 312 completed with results

Key Signals

201 with results78% success88 terminated

Data Visualizations

Phase Distribution

539Total
Not Applicable (28)
Early P 1 (3)
P 1 (216)
P 2 (250)
P 3 (34)
P 4 (8)

Trial Status

Completed312
Terminated88
Recruiting66
Unknown50
Active Not Recruiting45
Withdrawn18

Trial Success Rate

78.0%

Benchmark: 86.6%

Based on 312 completed trials

Clinical Trials (596)

Showing 20 of 20 trials
NCT04537871Active Not Recruiting

Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study

NCT05564390Phase 2Recruiting

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

NCT02732184Phase 1Completed

A Multiple Dose, Dose Escalation Trial of AEB1102 in Patients With AML or MDS

NCT07763054Recruiting

Low-dose Liposomal Amphotericin B for Antifungal Prophylaxis in Prolonged Neutropenia Patients

NCT07758218Phase 1Not Yet Recruiting

Allogeneic iNKT Cell Therapy (agenT-797) After SCT

NCT04708054Phase 2Recruiting

Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS

NCT06492707Phase 1Suspended

DR-18 to Prevent or Treat Acute Myeloid Leukemia or Myelodysplastic Syndrome Relapse After Hematopoietic Cell Transplantation, the DR. DREAM Trial

NCT06577441Phase 2RecruitingPrimary

Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

NCT00392353Phase 1Active Not Recruiting

Vorinostat and Azacitidine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia

NCT02861417Phase 2Active Not Recruiting

Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant

NCT04994808Phase 2Terminated

Treosulfan-Based Versus Clofarabine-Based Conditioning Before Donor Hematopoietic Stem Cell Transplant for the Treatment of Myelodysplastic Syndromes or Acute Myeloid Leukemia

NCT04281199Phase 1Active Not Recruiting

TBI Using IMRT (VMAT or Tomotherapy) for the Prevention of Pul Toxicities in Patients Undergoing Donor SCT

NCT07052006Phase 2Active Not RecruitingPrimary

A Phase 2a Study of HT-6184 in Subjects With IPSS-R Very Low, Low or Intermediate Risk MDS and Anemia

NCT07573111Phase 1Recruiting

Study of QUAIL-100 in Pediatric and Young Adult Participants With High-Risk Hematologic Malignancies Who Have Received a Hematopoietic Stem Cell Transplantation

NCT06287944Phase 1Recruiting

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

NCT01522976Phase 2Active Not Recruiting

Azacitidine With or Without Lenalidomide or Vorinostat in Treating Patients With Higher-Risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia

NCT05600894Phase 2Active Not Recruiting

Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm

NCT05457556Phase 3Active Not Recruiting

Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

NCT07285044Phase 2Recruiting

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

NCT02727803Phase 2Recruiting

Personalized NK Cell Therapy in CBT

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