Key Insights

Highlights

Success Rate

78% trial completion

Published Results

201 trials with published results (33%)

Research Maturity

314 completed trials (52% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

14.8%

89 terminated out of 602 trials

Success Rate

77.9%

-8.7% vs benchmark

Late-Stage Pipeline

7%

42 trials in Phase 3/4

Results Transparency

64%

201 of 314 completed with results

Key Signals

201 with results78% success89 terminated

Data Visualizations

Phase Distribution

542Total
Not Applicable (29)
Early P 1 (3)
P 1 (217)
P 2 (251)
P 3 (34)
P 4 (8)

Trial Status

Completed314
Terminated89
Recruiting66
Unknown50
Active Not Recruiting46
Withdrawn18

Trial Success Rate

77.9%

Benchmark: 86.6%

Based on 314 completed trials

Clinical Trials (602)

Showing 20 of 20 trials
NCT01494103Phase 1Active Not Recruiting

Administration of Donor T Cells With the Caspase-9 Suicide Gene

NCT06577441Phase 2RecruitingPrimary

Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

NCT00843882Phase 3Active Not Recruiting

Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia

NCT06419634Phase 1Terminated

Study of BMS-986497 (ORM-6151) as a Monotherapy, in Double and Triple Combination With Azacitidine and Venetoclax in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

NCT01985061Phase 2CompletedPrimary

Evaluation of 3 Different Doses of IV Busulfan

NCT06484062Phase 1Recruiting

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

NCT03770429Phase 1Active Not Recruiting

AZD6738 for Patients With Progressive MDS or CMML

NCT07285044Phase 2Recruiting

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

NCT03560752Phase 1Active Not Recruiting

CMV-MVA Triplex Vaccination of Stem Cell Donors in Preventing CMV Viremia in Participants With Allogeneic Transplant

NCT03494569Phase 1Suspended

Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome

NCT06820268Phase 1Recruiting

A Study of XS-04 in Patients With Relapsed or Refractory Hematologic Malignancies

NCT05564390Phase 2Recruiting

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

NCT03661307Phase 1Recruiting

Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

NCT07463820Phase 2Not Yet RecruitingPrimary

A Trial Comparing Three Different Treatment Options for Adults With Low-Risk Myelodysplasia and Anemia (A MyeloMATCH Treatment Trial)

NCT07346105Unknown

Orca-T Expanded Access Program Study for Patients With Advanced Hematologic Malignancies

NCT07780552Not Yet Recruiting

CHIP in Health and Disease

NCT07422480Phase 3RecruitingPrimary

A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

NCT03630991Phase 1Recruiting

Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy

NCT04734990Phase 1Active Not Recruiting

Seclidemstat and Azacitidine for the Treatment of Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia

NCT07052006Phase 2Active Not RecruitingPrimary

A Phase 2a Study of HT-6184 in Subjects With IPSS-R Very Low, Low or Intermediate Risk MDS and Anemia

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