Multiple Sclerosis, Primary Progressive
29
4
9
17
Key Insights
Highlights
Success Rate
100% trial completion (above average)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 40/100
0.0%
0 terminated out of 29 trials
100.0%
+13.5% vs benchmark
21%
6 trials in Phase 3/4
29%
5 of 17 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 17 completed trials
Clinical Trials (29)
A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Ocrelizumab in Adult Participants With Primary Progressive Multiple Sclerosis
Motor Asymmetry in Progressive Multiple Sclerosis Patients
Neuroprotection With N-acetyl Cysteine for Patients With Progressive Multiple Sclerosis
Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy
A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell ( CAR-T) Therapy in Subjects With Non-relapsing and Progressive Forms of Multiple Sclerosis
A Study to Evaluate the Efficacy and Safety of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis
Cognition Evolution and MRI Markers in PPMS Patients on 2 Years
Clinnova-MS: A Prospective Cohort Study of Patients With Multiple Sclerosis (Switzerland)
PET Study of PIPE-791 in Healthy Volunteers and Volunteers With PrMS and IPF
A Study of Allogeneic Hematopoietic Cell Transplantation for Primary Progressive Multiple Sclerosis
KYSA-7: A Study of Anti-CD19 CAR T-Cell Therapy, in Subjects With Refractory Primary and Secondary Progressive Multiple Sclerosis
The Effects of In-phase Bilateral Exercise in People with Progressive Multiple Sclerosis
An Observational Biomarker Study in Multiple Sclerosis (MS) Patients
Study to Explore the Mechanism of Action of Ocrelizumab and B-Cell Biology in Participants With Relapsing Multiple Sclerosis (RMS) or Primary Progressive Multiple Sclerosis (PPMS)
Exercise Effects in Multiple Sclerosis
MS-ResearchBiomarkerS
A Study of Ocrelizumab in Participants With Primary Progressive Multiple Sclerosis
Improving Cognition in People With Progressive Multiple Sclerosis Using Aerobic Exercise and Cognitive Rehabilitation
Intranasal Insulin for Improving Cognitive Function in Multiple Sclerosis
Imaging of Intracerebral Inflammation in MS