Key Insights

Highlights

Success Rate

76% trial completion

Published Results

14 trials with published results (28%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

10.0%

5 terminated out of 50 trials

Success Rate

76.2%

-10.4% vs benchmark

Late-Stage Pipeline

4%

2 trials in Phase 3/4

Results Transparency

88%

14 of 16 completed with results

Key Signals

14 with results76% success

Data Visualizations

Phase Distribution

48Total
Not Applicable (1)
Early P 1 (1)
P 1 (9)
P 2 (35)
P 3 (2)

Trial Status

Completed16
Unknown9
Recruiting8
Active Not Recruiting6
Terminated5
Withdrawn3

Trial Success Rate

76.2%

Benchmark: 86.5%

Based on 16 completed trials

Clinical Trials (50)

Showing 20 of 20 trials
NCT05111574Phase 2Active Not Recruiting

Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

NCT03698019Phase 2Active Not Recruiting

A Study to Compare the Administration of Pembrolizumab After Surgery Versus Administration Both Before and After Surgery for High-Risk Melanoma

NCT03178123Phase 2TerminatedPrimary

The Study of JS001 Compared to High-Dose Interferon In Patients With Mucosal Melanoma That Has Been Removed by Surgery

NCT07230613Phase 2Recruiting

Neo-adjuvant Immunotherapy in Patients With Localized Melanoma

NCT06424626Phase 1Enrolling By Invitation

A Trial of AK104 or AK112 in Combination With Axitinib in Patients With Metastatic Mucosal Melanoma

NCT01989572Phase 3Completed

Sargramostim, Vaccine Therapy, or Sargramostim and Vaccine Therapy in Preventing Disease Recurrence in Patients With Melanoma That Has Been Removed By Surgery

NCT06319196Phase 2Recruiting

Clear Me: Interception Trial to Detect and Clear Molecular Residual Disease in Patients With High-risk Melanoma

NCT00937937Phase 2Active Not Recruiting

Dinaciclib in Treating Patients With Stage IV Melanoma

NCT07600476Phase 1Recruiting

A First-in-Human Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of KUP-101A in Patients With Selected Advanced Solid Tumors

NCT05628883Phase 1Completed

Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma

NCT07506447Completed

The Value of [18F]FDG PET/CT Imaging in Prognostic Evaluation of Mucosal Melanoma

NCT07076550Phase 1Recruiting

A Phase 1-1b Study to Evaluate the Safety, Efficacy and Dosimetry of Study Drug A9-3408 in Subjects With Metastatic Melanoma

NCT02858869Phase 1Completed

Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain Metastases

NCT06999980Phase 2Recruiting

Neo IRENIE (NEOadjuvant Ipilimumab, RElatlimab, NIvolumab Evaluation)

NCT05384496Phase 2RecruitingPrimary

Axitinib and Nivolumab for the Treatment of Mucosal Melanoma

NCT07400302Phase 2RecruitingPrimary

Sintilimab Combined With Chemotherapy for Adjuvant Treatment of Mucosal Melanoma After Surgery

NCT04645680Phase 2Active Not Recruiting

Diet and Immune Effects Trial: DIET- A Randomized Double Blinded Dietary Intervention Study in Patients With Metastatic Melanoma Receiving Immunotherapy

NCT07347444Phase 2Not Yet Recruiting

Iparomlimab and Tuvoraleimab Injection in Combination With Bevacizumab, Albumin-bound Paclitaxel, and Carboplatin as First- or Second-line Treatment for Patients With Advanced Acral and Mucosal Melanoma

NCT07236528Phase 2Not Yet RecruitingPrimary

Combination of Carilizumab, Apatinib, and Radiotherapy for Advanced Mucosal Melanoma

NCT03611868Phase 1Active Not Recruiting

A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors

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