Key Insights

Highlights

Success Rate

80% trial completion

Published Results

14 trials with published results (29%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

8.2%

4 terminated out of 49 trials

Success Rate

80.0%

-6.5% vs benchmark

Late-Stage Pipeline

4%

2 trials in Phase 3/4

Results Transparency

88%

14 of 16 completed with results

Key Signals

14 with results80% success

Data Visualizations

Phase Distribution

47Total
Not Applicable (1)
Early P 1 (1)
P 1 (8)
P 2 (35)
P 3 (2)

Trial Status

Completed16
Unknown10
Recruiting8
Active Not Recruiting5
Terminated4
Not Yet Recruiting3

Trial Success Rate

80.0%

Benchmark: 86.5%

Based on 16 completed trials

Clinical Trials (49)

Showing 20 of 20 trials
NCT05111574Phase 2Recruiting

Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

NCT03698019Phase 2Active Not Recruiting

A Study to Compare the Administration of Pembrolizumab After Surgery Versus Administration Both Before and After Surgery for High-Risk Melanoma

NCT00937937Phase 2Active Not Recruiting

Dinaciclib in Treating Patients With Stage IV Melanoma

NCT05628883Phase 1Completed

Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma

NCT07506447Completed

The Value of [18F]FDG PET/CT Imaging in Prognostic Evaluation of Mucosal Melanoma

NCT07076550Phase 1Recruiting

A Phase 1-1b Study to Evaluate the Safety, Efficacy and Dosimetry of Study Drug A9-3408 in Subjects With Metastatic Melanoma

NCT02858869Phase 1Completed

Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain Metastases

NCT06999980Phase 2Recruiting

Neo IRENIE (NEOadjuvant Ipilimumab, RElatlimab, NIvolumab Evaluation)

NCT05384496Phase 2RecruitingPrimary

Axitinib and Nivolumab for the Treatment of Mucosal Melanoma

NCT07230613Phase 2Recruiting

Neo-adjuvant Immunotherapy in Patients With Localized Melanoma

NCT07400302Phase 2RecruitingPrimary

Sintilimab Combined With Chemotherapy for Adjuvant Treatment of Mucosal Melanoma After Surgery

NCT04645680Phase 2Active Not Recruiting

Diet and Immune Effects Trial: DIET- A Randomized Double Blinded Dietary Intervention Study in Patients With Metastatic Melanoma Receiving Immunotherapy

NCT07347444Phase 2Not Yet Recruiting

Iparomlimab and Tuvoraleimab Injection in Combination With Bevacizumab, Albumin-bound Paclitaxel, and Carboplatin as First- or Second-line Treatment for Patients With Advanced Acral and Mucosal Melanoma

NCT06319196Phase 2Recruiting

Clear Me: Interception Trial to Detect and Clear Molecular Residual Disease in Patients With High-risk Melanoma

NCT07236528Phase 2Not Yet RecruitingPrimary

Combination of Carilizumab, Apatinib, and Radiotherapy for Advanced Mucosal Melanoma

NCT03611868Phase 1Active Not Recruiting

A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors

NCT05086692Phase 1Recruiting

A Beta-only IL-2 ImmunoTherapY Study

NCT04830124Phase 2Terminated

Nemvaleukin Alfa Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Cutaneous or Mucosal Melanoma - ARTISTRY-6

NCT05436990Phase 2Terminated

Antitumor Activity of Vactosertib in Combination With Pembrolizumab in Acral and Mucosal Melanoma Patients Progressed From Prior Immune Check Point Inhibitor

NCT03033576Phase 2Completed

Testing Treatment With Ipilimumab and Nivolumab Compared to Treatment With Ipilimumab Alone in Advanced Melanoma

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