Key Insights

Highlights

Success Rate

97% trial completion (above average)

Published Results

19 trials with published results (27%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

1.4%

1 terminated out of 70 trials

Success Rate

97.3%

+10.8% vs benchmark

Late-Stage Pipeline

4%

3 trials in Phase 3/4

Results Transparency

53%

19 of 36 completed with results

Key Signals

19 with results97% success

Data Visualizations

Phase Distribution

50Total
Not Applicable (41)
Early P 1 (1)
P 1 (3)
P 2 (2)
P 3 (1)
P 4 (2)

Trial Status

Completed36
Unknown13
Recruiting10
Active Not Recruiting5
Withdrawn4
Not Yet Recruiting1

Trial Success Rate

97.3%

Benchmark: 86.5%

Based on 36 completed trials

Clinical Trials (70)

Showing 20 of 20 trials
NCT03242642Not ApplicableRecruitingPrimary

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

NCT07520656Recruiting

Impact of Transcatheter Aortic Valve Implantation and Mitral Valve Repair on Sleep-Disordered Breathing

NCT05051033Not ApplicableRecruitingPrimary

Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)

NCT03170349Not ApplicableCompletedPrimary

The CLASP Study Edwards PASCAL TrAnScatheter Mitral Valve RePair System Study

NCT07296016Not Yet Recruiting

The Asia-Pacific Mitral & Tricuspid Valve-in-Valve/Valve-in-Ring Registry

NCT07227675Not ApplicableCompleted

Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional MR

NCT04198870Not ApplicableActive Not RecruitingPrimary

MitraClip REPAIR MR Study

NCT03193801Not ApplicableActive Not Recruiting

PARTNER 3 Trial - Mitral Valve in Valve

NCT03039855Not ApplicableCompletedPrimary

Tiara™ Transcatheter Mitral Valve Replacement Study

NCT02321514Not ApplicableCompletedPrimary

Expanded Clinical Study of the Tendyne Mitral Valve System

NCT04177394Active Not RecruitingPrimary

MitraClip EXPAND G4 Study

NCT06805253Recruiting

Left Ventricular Reverse Remodeling Evaluation After Surgical Correction of Aortic Regurgitation

NCT02276547Not ApplicableActive Not RecruitingPrimary

Early Feasibility Study of the Neovasc Tiara™ Mitral Valve System

NCT00853632Not ApplicableCompleted

Magna® Mitral Pericardial Bioprostheses Post-Approval Study Protocol

NCT06959836Completed

Post-market Safety and Performance Outcomes of the VIVERE® Bovine Pericardial Bioprosthetic Valve

NCT06465745Not ApplicableRecruiting

AltaValve Pivotal Trial

NCT05902897Completed

Aortic or Mitral Valve Replacement With the Braile Biomédica® Bovine Pericardium Valvular Bioprosthesis

NCT04195984Not ApplicableRecruitingPrimary

Mi-thos® Transcatheter Mitral Valve Replacement Study

NCT04795856Early Phase 1WithdrawnPrimary

Understanding the Metabolic and Functional Derangement of Primary Mitral Regurgitation: a Feasibility Study Using Carbon 11(C-11) Acetate Cardiac Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI)

NCT04281940Not ApplicableCompleted

Chordal Repair for Transcatheter Mitral Valve Repair (TMVr)

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