Key Insights

Highlights

Success Rate

90% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

5.6%

4 terminated out of 72 trials

Success Rate

90.0%

+3.5% vs benchmark

Late-Stage Pipeline

6%

4 trials in Phase 3/4

Results Transparency

22%

8 of 36 completed with results

Key Signals

8 with results90% success

Data Visualizations

Phase Distribution

42Total
Not Applicable (18)
Early P 1 (1)
P 1 (7)
P 2 (12)
P 3 (3)
P 4 (1)

Trial Status

Completed36
Recruiting17
Unknown7
Terminated4
Enrolling By Invitation3
Active Not Recruiting2

Trial Success Rate

90.0%

Benchmark: 86.5%

Based on 36 completed trials

Clinical Trials (72)

Showing 20 of 20 trials
NCT07558213Active Not Recruiting

A Multi-Dimensional Model of cAre and transItion for Patients With cOmplex RAre Diseases

NCT04322734Recruiting

Transgenerational Metabolic-Immune Biomarkers of Neurological and Neurodevelopmental Disorders

NCT06535646Not ApplicableCompletedPrimary

Digital Health Technology for People With Mitochondrial Disease

NCT06504433RecruitingPrimary

The Natural History of Mitochondrial Diseases

NCT04378075Phase 2TerminatedPrimary

A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy

NCT07450690Not ApplicableRecruitingPrimary

Exercise Training Effects on Muscle Function in Adults With Mitochondrial Myopathy

NCT05958706Recruiting

Mitochondrial Substrate Utilization in the Diabetic Human Heart

NCT04086329Phase 1Recruiting

Validation of Oxygen Nanosensor in Mitochondrial Myopathy

NCT01694940Recruiting

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

NCT06451757Phase 3RecruitingPrimary

KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases

NCT04734626Enrolling By InvitationPrimary

CrCest Study in Primary Mitochondrial Disease

NCT05645874CompletedPrimary

Reference Values of Intraepidermal Nerve Fiber Density in Children and Small Fiber Neuropathy in Neurodevelopmental Disorders

NCT05569122Phase 1Recruiting

Applying pGz in Mitochondrial Disease

NCT05162768Phase 3Completed

Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD)

NCT01148550Suspended

Longitudinal Study of Mitochondrial Hepatopathies

NCT05483738Not ApplicableActive Not RecruitingPrimary

The Impact of Mitochondrial Dysfunction on Human Bone Cell Metabolism and Remodelling

NCT04113447RecruitingPrimary

Mitochondrial Donation: An 18 Month Outcome Study.

NCT06080581Completed

Mitochondrial Dysfunctions Driving Insulin Resistance

NCT06080568CompletedPrimary

Human Mitochondrial Stress-driven Obesity Resistance

NCT06080594Not ApplicableCompleted

Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance

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