Key Insights

Highlights

Success Rate

44% trial completion

Published Results

11 trials with published results (9%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

15.3%

19 terminated out of 124 trials

Success Rate

44.1%

-42.5% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

73%

11 of 15 completed with results

Key Signals

11 with results44% success19 terminated

Data Visualizations

Phase Distribution

118Total
Not Applicable (6)
Early P 1 (1)
P 1 (100)
P 2 (11)

Trial Status

Recruiting53
Terminated19
Active Not Recruiting17
Completed15
Unknown11
Not Yet Recruiting6

Trial Success Rate

44.1%

Benchmark: 86.6%

Based on 15 completed trials

Clinical Trials (124)

Showing 20 of 20 trials
NCT04585750Phase 1Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

NCT06465069Phase 1RecruitingPrimary

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

NCT07213817Phase 1Recruiting

A Study to Assess the Safety, Tolerability, Pharmacokinetic, Pharmacodynamic, Immunogenicity and Antitumour Activity of IPN60300 in Adults With Locally Advanced or Metastatic Solid Tumours

NCT05875168Phase 1Recruiting

First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors

NCT05103358Phase 2Completed

Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)

NCT05118789Phase 1Recruiting

A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)

NCT06302621Phase 1Recruiting

Pemigatinib + Afatinib in Advanced Refractory Solid Tumors

NCT05259709Phase 1Recruiting

A Study of ImmunoPet Imaging Using 89Zr-DFO-REGN5054 in Adult Participants With Solid Cancers Treated With Cemiplimab

NCT05863052Active Not Recruiting

Analyzing Clinical Outcomes and Genomic Data of American Indian Patient Population

NCT07172802Phase 1Recruiting

A Study of GI-108, an Anti-CD73-IgG4 Fc-IL-2v Bispecific Fusion Protein, as Monotherapy in Patients With Advanced or Metastatic Solid Tumors

NCT05898399Phase 1Recruiting

Study of ART6043 in Advanced/Metastatic Solid Tumors Patients (POLKA)

NCT04977453Phase 1Recruiting

GI-101/GI-101A as a Single Agent or in Combination With Pembrolizumab or Lenvatinib in Advanced Solid Tumors

NCT05081609Phase 1Active Not Recruiting

A Study to Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies

NCT07746141Phase 1Recruiting

A First-in-Human Study Investigating BG-85738 Alone or in Combination With Other Antitumor Agents in Patients With Advanced or Metastatic Solid Tumors With Rat Sarcoma Virus (RAS) Mutations

NCT04471987Phase 1Recruiting

Safety and Early Signs of Efficacy of IL12-L19L19.

NCT06266299Phase 1Recruiting

A Study of KK2269 in Adult Participants With Solid Tumors

NCT06440005Phase 1Recruiting

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

NCT06561685Phase 1RecruitingPrimary

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

NCT07602842Phase 1Recruiting

A Study of IDP-001 in Advanced or Metastatic Solid Tumors

NCT07213830Phase 1Recruiting

A Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies

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