Key Insights

Highlights

Success Rate

41% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

15.6%

19 terminated out of 122 trials

Success Rate

40.6%

-45.9% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

77%

10 of 13 completed with results

Key Signals

10 with results41% success19 terminated

Data Visualizations

Phase Distribution

117Total
Not Applicable (6)
Early P 1 (1)
P 1 (99)
P 2 (11)

Trial Status

Recruiting52
Terminated19
Active Not Recruiting18
Completed13
Unknown11
Not Yet Recruiting6

Trial Success Rate

40.6%

Benchmark: 86.5%

Based on 13 completed trials

Clinical Trials (122)

Showing 20 of 20 trials
NCT07213817Phase 1Recruiting

A Study to Assess the Safety, Tolerability, Pharmacokinetic, Pharmacodynamic, Immunogenicity and Antitumour Activity of IPN60300 in Adults With Locally Advanced or Metastatic Solid Tumours

NCT07213830Phase 1Recruiting

A Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies

NCT07602842Phase 1Recruiting

A Study of IDP-001 in Advanced or Metastatic Solid Tumors

NCT07524140Phase 1Recruiting

A First-in-Human Study of ZE94-0605 in Patients With Advanced Solid Tumors

NCT06465069Phase 1RecruitingPrimary

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

NCT06724042Phase 1Not Yet Recruiting

Study of ISM5939 in Patients With Advanced and/or Metastatic Solid Tumors

NCT06545942Phase 1Recruiting

Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

NCT06974110Phase 1Recruiting

Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors

NCT04447651Active Not RecruitingPrimary

Patient Response to Immunotherapy Using Spliceosome Mutational Markers (PRISMM)

NCT06607185Phase 1Active Not Recruiting

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

NCT05875168Phase 1Recruiting

First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors

NCT05673928Phase 2RecruitingPrimary

A Phase II Study of Tucatinib and Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2-positive Metastatic Solid Tumors and Metastases to Brain (TUCATEMEB)

NCT06657144Phase 1RecruitingPrimary

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

NCT06587295Phase 1Recruiting

Intramuscular ACM-CpG Monotherapy in Patients With Advanced/Metastatic Solid Tumors With Prior Response to Immunotherapy Alone or in Combination With Chemotherapy

NCT07681882Phase 1Not Yet Recruiting

First-in-Human Trial of DS1025a in Participants With Advanced Solid Tumors

NCT06803680Phase 1Recruiting

A Study of BGB-B455 in Adults With Advanced or Metastatic Solid Tumors

NCT04585750Phase 1Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

NCT06952010Phase 1Recruiting

A Study of XB628 Alone and in Combination With Zanzalintinib in Participants With Recurrent Advanced or Metastatic Solid Tumors

NCT05694715Phase 1RecruitingPrimary

Combination Therapy in Cancers With Mutations in DNA Repair Genes

NCT07638371Phase 1Recruiting

FORTRAS: A Study of MSK-TCR5 in People With Solid Tumor Cancers

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