Key Insights

Highlights

Success Rate

79% trial completion

Published Results

29 trials with published results (28%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

11.8%

12 terminated out of 102 trials

Success Rate

78.6%

-8.0% vs benchmark

Late-Stage Pipeline

8%

8 trials in Phase 3/4

Results Transparency

66%

29 of 44 completed with results

Key Signals

29 with results79% success12 terminated

Data Visualizations

Phase Distribution

102Total
Not Applicable (2)
Early P 1 (1)
P 1 (58)
P 2 (33)
P 3 (8)

Trial Status

Completed44
Active Not Recruiting20
Recruiting12
Terminated12
Withdrawn7
Unknown3

Trial Success Rate

78.6%

Benchmark: 86.5%

Based on 44 completed trials

Clinical Trials (102)

Showing 20 of 20 trials
NCT04514497Phase 1Active Not Recruiting

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer

NCT05372614Phase 1Recruiting

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

NCT04616534Phase 1Active Not Recruiting

Testing the Addition of an Anti-cancer Drug, Elimusertib (BAY 1895344) ATR Inhibitor, to the Chemotherapy Treatment (Gemcitabine) for Advanced Pancreatic and Ovarian Cancer, and Advanced Solid Tumors

NCT07409272Phase 3Recruiting

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

NCT05034627Phase 1Completed

Calaspargase Pegol-Mnkl and Cobimetinib for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer

NCT07189195Phase 1Recruiting

TR-002 for the Treatment of Advanced Unresectable Metastatic Solid Tumors Unresectable or Metastatic, Refractory Pancreatic Adenocarcinoma

NCT03816163Phase 2Active Not Recruiting

A Study of Zolbetuximab (IMAB362) in Adults With Pancreatic Cancer

NCT07700212Phase 1Not Yet RecruitingPrimary

A Phase 1 Trial Of Safety And Initial Efficacy Of Vagal Nerve Blockade For Cancer-Induced Cachexia In Patients With Metastatic Pancreatic Adenocarcinoma

NCT04233866Phase 2Active Not RecruitingPrimary

Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread

NCT04548752Phase 2Active Not RecruitingPrimary

Testing the Addition of Pembrolizumab, an Immunotherapy Cancer Drug to Olaparib Alone as Therapy for Patients With Pancreatic Cancer That Has Spread With Inherited BRCA Mutations

NCT04975516Phase 2TerminatedPrimary

Standard of Care Chemotherapy With or Without Stereotactic Body Radiation Therapy for Oligometastatic Pancreatic Cancer

NCT06381154Phase 2Active Not Recruiting

Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advanced or Metastatic Pancreatic Cancer

NCT02498613Phase 2Active Not Recruiting

A Phase 2 Study of Cediranib in Combination With Olaparib in Advanced Solid Tumors

NCT03269526Phase 1Completed

BATs Treatment for Pancreatic Cancer, Phase Ib/II

NCT07226856Phase 2RecruitingPrimary

BMS-986340 in Combination With Nivolumab, Gemcitabine and Nab-paclitaxel for the Treatment of Metastatic and Recurrent Pancreatic Adenocarcinoma

NCT07619313Phase 1Not Yet Recruiting

AB801 in Combination With Chemotherapy and Immunotherapy for the Treatment of Patients With Borderline Resectable, Locally Advanced or Metastatic Cholangiocarcinoma or Pancreatic Cancer

NCT01585805Phase 2Active Not Recruiting

Gemcitabine Hydrochloride and Cisplatin With or Without Veliparib or Veliparib Alone in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

NCT03257761Phase 1Active Not Recruiting

Guadecitabine and Durvalumab in Treating Patients With Advanced Liver, Pancreatic, Bile Duct, or Gallbladder Cancer

NCT07608627Phase 1Not Yet Recruiting

64Cu-DOTA A2 scFv-Fc2 DM With Positron Emission Tomography for the Imaging of Patients With Locally Advanced or Metastatic PSCA-Expressing Pancreatic Cancer

NCT03095781Phase 1Completed

Pembrolizumab and XL888 in Patients With Advanced Gastrointestinal Cancer

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