Key Insights

Highlights

Success Rate

78% trial completion

Published Results

102 trials with published results (16%)

Research Maturity

298 completed trials (48% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

13.5%

84 terminated out of 622 trials

Success Rate

78.0%

-8.5% vs benchmark

Late-Stage Pipeline

9%

55 trials in Phase 3/4

Results Transparency

34%

102 of 298 completed with results

Key Signals

102 with results78% success84 terminated

Data Visualizations

Phase Distribution

545Total
Not Applicable (78)
Early P 1 (8)
P 1 (226)
P 2 (178)
P 3 (53)
P 4 (2)

Trial Status

Completed298
Terminated84
Recruiting83
Unknown70
Active Not Recruiting44
Withdrawn30

Trial Success Rate

78.0%

Benchmark: 86.6%

Based on 298 completed trials

Clinical Trials (622)

Showing 20 of 20 trials
NCT01856296Not ApplicableCompletedPrimary

A Study to Select Rational Therapeutics Based on the Analysis of Matched Tumor and Normal Biopsies in Subjects With Advanced Malignancies

NCT04585750Phase 1Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

NCT00068003Enrolling By Invitation

Harvesting Cells for Experimental Cancer Treatments

NCT05065736Early Phase 1TerminatedPrimary

Using a PET Imaging Agent, 18F-Clofarabine (CFA), to Measure Deoxycytidine Kinase Activity in Metastatic Cancer

NCT05010629Phase 2Active Not Recruiting

9-ING-41 Plus Carboplatin in Salivary Gland Carcinoma

NCT03409016Active Not Recruiting

Biomarkers of Immune-Related Toxicity

NCT05853575Phase 2Active Not Recruiting

Trial of Two Adagrasib Dosing Regimens in NSCLC With KRAS G12C Mutation (KRYSTAL 21)

NCT05245136Recruiting

Augsburg Longitudinal Plasma Study for the Evaluation of Liquid Biopsy as Diagnostic Tool.

NCT04657068Phase 1Recruiting

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

NCT05475171Phase 2SuspendedPrimary

Triage of Advanced Cervical Cancer Through Immunotherapy Induction (TRACTION)

NCT05267626Phase 1Recruiting

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

NCT03785249Phase 1Active Not Recruiting

Phase 1/2 Study of MRTX849 in Patients With Cancer Having a KRAS G12C Mutation KRYSTAL-1

NCT07043608Phase 2Recruiting

Zanzalintinib for Metastatic Clear Cell Renal Cell Carcinoma With Bone Metastases

NCT03693014Phase 2Active Not RecruitingPrimary

A Study of Several Radiation Doses for Patients With Progression on Immunotherapy/Checkpoint Inhibitors

NCT06771219Phase 1Recruiting

SLV-154 Treatment of Advanced Cancers

NCT05714553Phase 1Terminated

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

NCT07197671Phase 1RecruitingPrimary

Y-NM600 in Patients Receiving Anti-PD-1 or Anti-PD-L1 for Metastatic Cancer

NCT05919264Phase 1Recruiting

FOG-001 in Locally Advanced or Metastatic Solid Tumors

NCT04989725Phase 2RecruitingPrimary

Stereotactic Ablative Radiotherapy for Oligo-Progressive Disease REfractory to Systemic Therapy in Metastatic Cancer

NCT02711553Phase 2Active Not Recruiting

A Study of Ramucirumab (LY3009806) or Merestinib (LY2801653) in Advanced or Metastatic Biliary Tract Cancer

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