Key Insights

Highlights

Success Rate

74% trial completion

Published Results

12 trials with published results (39%)

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 27/100

Termination Rate

19.4%

6 terminated out of 31 trials

Success Rate

73.9%

-12.6% vs benchmark

Late-Stage Pipeline

39%

12 trials in Phase 3/4

Results Transparency

71%

12 of 17 completed with results

Key Signals

12 with results74% success

Data Visualizations

Phase Distribution

29Total
Not Applicable (5)
P 1 (3)
P 2 (9)
P 3 (7)
P 4 (5)

Trial Status

Completed17
Terminated6
Recruiting4
Unknown2
Active Not Recruiting1
Not Yet Recruiting1

Trial Success Rate

73.9%

Benchmark: 86.6%

Based on 17 completed trials

Clinical Trials (31)

Showing 20 of 20 trials
NCT04026516Not ApplicableCompletedPrimary

CAVA: Dizziness Trial

NCT06859788Phase 3Active Not RecruitingPrimary

SPI-1005 for the Treatment of Meniere's Disease (Open Label)

NCT04806282RecruitingPrimary

Deep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures, and Discovery of Therapeutic Targets

NCT02603081Phase 1CompletedPrimary

Study to Evaluate SPI-1005 in Adults With Meniere's Disease

NCT03587701Phase 2Recruiting

Effects of Anakinra in Subjects With Corticosteroid-resistant/Intolerant Meniere's Disease and Autoimmune Inner Ear Disease

NCT07518069Recruiting

Genetic and Biohumoral Factors Involved in Menière's Disease and Their Correlation With Phenotypes

NCT06765993Phase 2Not Yet RecruitingPrimary

Efficacy and Safety of Isosorbide Oral Solution in Patients With Meniere's Disease

NCT06001593Phase 1RecruitingPrimary

Modulating Auditory Symptoms and Vertigo of Meniere's Disease by Non-invasive Mastoid Electric Stimulation

NCT03325790Phase 2CompletedPrimary

SPI-1005 for the Treatment of Patients With Meniere's Disease

NCT02768662Phase 3TerminatedPrimary

A 6-Month Extension Study of OTO-104 in Meniere's Disease

NCT02717442Phase 3TerminatedPrimary

Study of OTO-104 in Subjects With Unilateral Meniere's Disease

NCT02612337Phase 3CompletedPrimary

Study of OTO-104 in Subjects With Unilateral Meniere's Disease

NCT02706730Phase 3TerminatedPrimary

A 6-Month Extension Study of OTO-104 in Meniere's Disease

NCT02158585Phase 2CompletedPrimary

Study of Lamotrigine to Treat Ménière's Disease

NCT01526408Phase 3TerminatedPrimary

Famvir for Treatment of Hearing in Unilateral Meniere's Disease

NCT00145483Phase 4CompletedPrimary

Sildenafil For Meniere's Disease

NCT02530931Phase 4TerminatedPrimary

Evaluation of Inner Ear and Brain Structures With Contrast-enhanced MRI in Patients With Meniere's Disease

NCT00802529Phase 2CompletedPrimary

Transtympanic Gentamicin vs. Steroids in Refractory Meniere's Disease

NCT02309099Not ApplicableCompleted

Cochlear Implantation After Labyrinthectomy or a Translabyrinthine Surgical Approach

NCT02740387Phase 2TerminatedPrimary

Open Label Study of OTO-104 in Subjects With Meniere's Disease

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Research Network

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