Key Insights

Highlights

Success Rate

75% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

4.2%

2 terminated out of 48 trials

Success Rate

75.0%

-11.5% vs benchmark

Late-Stage Pipeline

8%

4 trials in Phase 3/4

Results Transparency

50%

3 of 6 completed with results

Key Signals

3 with results75% success

Data Visualizations

Phase Distribution

37Total
Not Applicable (3)
Early P 1 (1)
P 1 (8)
P 2 (21)
P 3 (3)
P 4 (1)

Trial Status

Recruiting18
Active Not Recruiting10
Unknown9
Completed6
Not Yet Recruiting2
Terminated2

Trial Success Rate

75.0%

Benchmark: 86.5%

Based on 6 completed trials

Clinical Trials (48)

Showing 20 of 20 trials
NCT07565285Phase 2Not Yet RecruitingPrimary

The Efficacy and Safety of PRTX007-003 Combined With Pembrolizumab in Resectable Stage III Melanoma

NCT04207086Phase 2Active Not RecruitingPrimary

A Phase II Study of Neoadjuvant Pembrolizumab & Lenvatinib for Resectable Stage III Melanoma

NCT04562129Phase 2RecruitingPrimary

IL2 With Ipilimumab Followed by Nivolumab in Stage 3 or 4 Melanoma Patients

NCT06295159Phase 2RecruitingPrimary

Neoadjuvant and Adjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma

NCT03620019Phase 2CompletedPrimary

Denosumab + PD-1 in Subjects With Stage III/ IV Melanoma

NCT05655312Phase 1Recruiting

MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma

NCT06771544Phase 2Recruiting

Metronomic Cyclophosphamide With Pembrolizumab in Checkpoint Inhibitor Refractory Melanoma

NCT04741997Early Phase 1RecruitingPrimary

Adjuvant Therapy Based on Pathologic Response After Neoadjuvant Encorafenib Binimetinib in Melanoma

NCT04305145Phase 2Active Not RecruitingPrimary

Infliximab for Treatment of Immune Checkpoint Inhibitor Colitis

NCT06199713Recruiting

Correlating Early FDG PET/CT and ctDNA in Immune Checkpoint Inhibitor (ICI)-Treated Melanoma Patients

NCT04526899Phase 2CompletedPrimary

A Study to Investigate the Novel Agent BNT111 and Cemiplimab in Combination or as Single Agents in Patients With Advanced Melanoma That Has Not Responded to Other Forms of Treatment

NCT03161431Phase 1Active Not RecruitingPrimary

SX-682 Treatment in Subjects With Metastatic Melanoma Concurrently Treated With Pembrolizumab

NCT04079166Phase 2Active Not Recruiting

SCIB1 and iSCIB1+ in Melanoma Patients Receiving Nivolumab With Ipilimumab or SCIB1 With Pembrolizumab (The SCOPE Study)

NCT06508775Not ApplicableRecruitingPrimary

Long-Term Follow-up of Patients Treated With Miltenyi Cell and Gene Therapies

NCT04013854Phase 2Active Not RecruitingPrimary

Adjuvant Treatment Determined By Pathological Response To Neoadjvuant Nivolumab

NCT04513028Not ApplicableRecruitingPrimary

Beta Glucan's Effect on Pembrolizumab Immunologic Response in Stage III-IV Melanoma

NCT05289193Phase 2Active Not Recruiting

CD8+ T Cell Imaging During Pre-surgery Immunotherapy in People With Melanoma

NCT04139902Phase 2Active Not RecruitingPrimary

Neoadjuvant PD-1 Inhibitor Dostarlimab (TSR-042) vs. Combination of Tim-3 Inhibitor Cobolimab (TSR-022) and PD-1 Inhibitor Dostarlimab (TSR-042) in Melanoma

NCT06551064Phase 1Active Not Recruiting

Assessment of PK Similarity of FYB206 in Comparison With Keytruda in Resected Stage II or III Melanoma Patients

NCT04598009Phase 2RecruitingPrimary

Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant Melanoma

Scroll to load more

Research Network

Activity Timeline