Key Insights

Highlights

Success Rate

50% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

15.0%

3 terminated out of 20 trials

Success Rate

50.0%

-36.5% vs benchmark

Late-Stage Pipeline

5%

1 trials in Phase 3/4

Results Transparency

67%

2 of 3 completed with results

Key Signals

2 with results50% success

Data Visualizations

Phase Distribution

16Total
Not Applicable (4)
Early P 1 (2)
P 1 (8)
P 2 (1)
P 3 (1)

Trial Status

Recruiting8
Not Yet Recruiting3
Terminated3
Completed3
Unknown2
Withdrawn1

Trial Success Rate

50.0%

Benchmark: 86.5%

Based on 3 completed trials

Clinical Trials (20)

Showing 20 of 20 trials
NCT05230758Phase 3RecruitingPrimary

Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour

NCT05057702Not ApplicableRecruiting

Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma and Ependymoma

NCT04185038Phase 1Recruiting

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

NCT06193759Phase 1RecruitingPrimary

Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT)

NCT06942039Early Phase 1Recruiting

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

NCT07390539Phase 1Not Yet Recruiting

B7-H3.CD28Z.CART in CNS Neoplasms

NCT07346157Phase 1Not Yet Recruiting

Liothyronine in Combination With BIT Regimen for Medulloblastoma With or Without Minimal Residual Disease

NCT06898684Not ApplicableRecruitingPrimary

Medulloblastoma Online Video-based Exercise Pilot Study

NCT02238899CompletedPrimary

Multicenter Register for Children and Young Adults With Intracranial Localized Medulloblastoma, CNS-PNET or Ependymoma

NCT03904862Phase 1TerminatedPrimary

Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery

NCT06959979Early Phase 1RecruitingPrimary

Novel Molecular Targets and Innovative Therapeutic Perspective in Medulloblastoma

NCT05298995Phase 1Recruiting

GD2-CAR T Cells for Pediatric Brain Tumours

NCT02624388Phase 2Terminated

Study of Genistein in Pediatric Oncology Patients (UVA-Gen001)

NCT04167618Phase 1TerminatedPrimary

177Lu-DTPA-Omburtamab Radioimmunotherapy for Recurrent or Refractory Medulloblastoma

NCT05406947Not Yet RecruitingPrimary

Establishment and Clinical Application of Risk Classification Model Based on Molecular Typing of Medulloblastoma in Children

NCT04860934Not ApplicableCompletedPrimary

Dual Task Training On Children With Ataxia After Medulloblastoma Resection

NCT04528316Not ApplicableCompleted

Physical Activity on Postural Stability and Coordination in Children With Posterior Fossa Tumor

NCT04174820UnknownPrimary

Child's Study of the Impact of PF Lesion on Motor Skills, Language, Cognitive Functioning and Social Cognition

NCT03288168UnknownPrimary

Children's and Adolescents' Medulloblastoma Molecular Subgroups in China

NCT01697514Phase 1WithdrawnPrimary

A Study of LY2940680 in Pediatric Medulloblastoma or Rhabdomyosarcoma

Showing all 20 trials

Research Network

Activity Timeline