Key Insights

Highlights

Success Rate

50% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

12.5%

5 terminated out of 40 trials

Success Rate

50.0%

-36.5% vs benchmark

Late-Stage Pipeline

5%

2 trials in Phase 3/4

Results Transparency

100%

5 of 5 completed with results

Key Signals

5 with results50% success

Data Visualizations

Phase Distribution

35Total
Not Applicable (2)
Early P 1 (1)
P 1 (19)
P 2 (11)
P 3 (1)
P 4 (1)

Trial Status

Recruiting18
Completed5
Active Not Recruiting5
Terminated5
Not Yet Recruiting4
Unknown3

Trial Success Rate

50.0%

Benchmark: 86.5%

Based on 5 completed trials

Clinical Trials (40)

Showing 20 of 20 trials
NCT07569965Phase 2Not Yet RecruitingPrimary

Frontline Risk-Adapted Optimization of Novel Targeted Immunotherapy Evaluation in High-Risk MCL

NCT02717624Phase 1Active Not RecruitingPrimary

A Study of Acalabrutinib in Combination With Rituximab + (Bendamustine or Venetoclax) in Subjects With MCL

NCT05131022Phase 1Recruiting

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

NCT04488354Phase 1Completed

Long-term Follow-up Study for Patients Treated With CLBR001 CAR-T

NCT04830137Phase 1Recruiting

A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies

NCT03547115Phase 1Terminated

A Study of Voruciclib Alone or in Combination With Venetoclax in Subjects With B-Cell Malignancies or AML

NCT04186520Phase 1Recruiting

CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies

NCT07412405Not ApplicableNot Yet Recruiting

This Clinical Trial is a Single-arm, Non-randomized Pilot Trial to Determine the Safety of Administering Autologous Anti-C19 Cells (ARI-0001) and the Feasibility of Local CAR-T Cell Production in Patients Over 18 Years of Age With Relapsed/Refractory (R/R) CD19+ Hematologic Malignancies, Including R

NCT02213926Phase 2Active Not RecruitingPrimary

An Open-label, Phase 2 Study of ACP-196 (Acalabrutinib) in Subjects With Mantle Cell Lymphoma

NCT07121946Phase 1Recruiting

This is a Phase 1 Study to Evaluate the Safety of LTZ-301 in Patients With Non-Hodgkin Lymphoma

NCT06043011Recruiting

Registry Platform Hematologic Malignancies (RUBIN) - Extension of Tumor Registry Lymphatic Neoplasms

NCT05665530Phase 1Completed

A Study of PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R Hematologic Malignancies

NCT07077512Phase 2Recruiting

Relmacabtagene Autoleucel Combined With Sintilimab for Relapsed/Refractory B-cell Lymphoma

NCT05716087Phase 2Active Not RecruitingPrimary

A Study of Rocbrutinib in Participants With Relapse or Refractory Mantle Cell Lymphoma

NCT05098613Phase 1Recruiting

Preliminary Safety and Tolerability of CD19x22 CAR T Cells in Adolescent and Adult R/R B-NHL Patients

NCT07285590Phase 2RecruitingPrimary

Clinical Trial to Evaluate the Efficacy and Safety of Pirtobrutinib With Rituximab in Patients With Mantle Cell Lymphoma

NCT02362035Phase 1Completed

ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies

NCT07272499Phase 2RecruitingPrimary

Orelabrutinib Plus Lisaftoclax and Rituximab in Untreated Mantle Cell Lymphoma With High-Risk Disease

NCT07264894Phase 4Not Yet RecruitingPrimary

ZSDT for the Treatment of R/R Mantle Cell Lymphoma After BTK Inhibitor Failure: a Multi-center Prospective Clinical Trial

NCT07257510Not ApplicableRecruitingPrimary

Pomalidomide Plus Orelabrutinib and Zuberitamab in Untreated Mantle Cell Lymphoma

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