Key Insights

Highlights

Success Rate

77% trial completion

Published Results

85 trials with published results (25%)

Research Maturity

139 completed trials (41% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

12.1%

41 terminated out of 338 trials

Success Rate

77.2%

-9.3% vs benchmark

Late-Stage Pipeline

8%

27 trials in Phase 3/4

Results Transparency

61%

85 of 139 completed with results

Key Signals

85 with results77% success41 terminated

Data Visualizations

Phase Distribution

309Total
Not Applicable (9)
Early P 1 (8)
P 1 (125)
P 2 (140)
P 3 (26)
P 4 (1)

Trial Status

Completed139
Recruiting64
Active Not Recruiting42
Terminated41
Unknown29
Withdrawn12

Trial Success Rate

77.2%

Benchmark: 86.6%

Based on 139 completed trials

Clinical Trials (338)

Showing 20 of 20 trials
NCT06697184Phase 1Recruiting

A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers.

NCT05887167Phase 1Recruiting

Feasibility and Safety of Collecting and Combining Autologous Hematopoietic Stem Cells With Chimeric Antigen Receptor (CAR) T-Cell Therapy in Subjects With Relapsed/Refractory Hematological Malignancies

NCT05458297Phase 2Active Not Recruiting

A Study of Zilovertamab Vedotin (MK-2140) as Monotherapy and in Combination in Participants With Aggressive and Indolent B-cell Malignancies (MK-2140-006)

NCT04765111Phase 2Active Not RecruitingPrimary

Acalabrutinib and Rituximab for the Treatment of Previously Untreated Mantle Cell Lymphoma

NCT05724121Recruiting

Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax

NCT05990465Phase 1Recruiting

LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies

NCT06533579Phase 1Recruiting

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

NCT05006716Phase 1Recruiting

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

NCT05976763Phase 3RecruitingPrimary

Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

NCT01804686Phase 3Recruiting

A Long-term Extension Study of PCI-32765 (Ibrutinib)

NCT07285044Phase 2Recruiting

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

NCT05365659Phase 1Recruiting

IKS03 in Patients With Advanced B Cell Non-Hodgkin Lymphomas

NCT06252675Phase 2RecruitingPrimary

Glofitamab With Pirtobrutinib for Relapsed or Refractory Mantle Cell Lymphoma

NCT03478514Phase 2Active Not RecruitingPrimary

Phase II Palbociclib +Ibrutinib in Mantle Cell Lymphoma

NCT04626791Phase 2Active Not RecruitingPrimary

Modified VR-CAP and Acalabrutinib as First Line Therapy for the Treatment of Transplant-Eligible Patients With Mantle Cell Lymphoma

NCT05861050Phase 1Recruiting

Glofitamab With Obinutuzumab, Venetoclax, and Lenalidomide for the Treatment of Patients With Newly Diagnosed High Risk Mantle Cell Lymphoma

NCT06742996Phase 3RecruitingPrimary

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)

NCT04115631Phase 2Active Not Recruiting

A Comparison of Three Chemotherapy Regimens for the Treatment of Patients With Newly Diagnosed Mantle Cell Lymphoma

NCT03267433Phase 3Active Not RecruitingPrimary

Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete Remission

NCT04783415Phase 2Active Not RecruitingPrimary

Acalabrutinib, Umbralisib, and Ublituximab for the Treatment of Previously Untreated Mantle Cell Lymphoma

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