Key Insights

Highlights

Success Rate

77% trial completion

Published Results

86 trials with published results (25%)

Research Maturity

138 completed trials (41% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

12.1%

41 terminated out of 339 trials

Success Rate

77.1%

-9.5% vs benchmark

Late-Stage Pipeline

8%

27 trials in Phase 3/4

Results Transparency

62%

86 of 138 completed with results

Key Signals

86 with results77% success41 terminated

Data Visualizations

Phase Distribution

310Total
Not Applicable (9)
Early P 1 (8)
P 1 (125)
P 2 (141)
P 3 (26)
P 4 (1)

Trial Status

Completed138
Recruiting64
Active Not Recruiting43
Terminated41
Unknown29
Withdrawn12

Trial Success Rate

77.1%

Benchmark: 86.6%

Based on 138 completed trials

Clinical Trials (339)

Showing 20 of 20 trials
NCT03872180Phase 2Active Not Recruiting

Bendamustine, Obinutuzumab, and Venetoclax in Patients With Untreated Mantle Cell Lymphoma

NCT05724121Recruiting

Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax

NCT05976763Phase 3RecruitingPrimary

Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

NCT03478514Phase 2Active Not RecruitingPrimary

Phase II Palbociclib +Ibrutinib in Mantle Cell Lymphoma

NCT06224309Recruiting

Preliminary Assessment of [18F]BL40 in PET/CT Scans

NCT06252675Phase 2RecruitingPrimary

Glofitamab With Pirtobrutinib for Relapsed or Refractory Mantle Cell Lymphoma

NCT01804686Phase 3Active Not Recruiting

A Long-term Extension Study of PCI-32765 (Ibrutinib)

NCT07285044Phase 2Recruiting

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

NCT05006716Phase 1Recruiting

A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies

NCT06742996Phase 3RecruitingPrimary

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)

NCT06697184Phase 1Recruiting

A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers.

NCT06784167Recruiting

Vaccine Responses in Patient With Multiple Myeloma and Non-Hodgkin Lymphoma After CAR-T Treatment

NCT06553872Phase 2RecruitingPrimary

Phase 2 Open Label Randomized Study of Pirtobrutinib and Brexucabtagene Autoleucel in R/R MCL

NCT05861050Phase 1Suspended

Glofitamab With Obinutuzumab, Venetoclax, and Lenalidomide for the Treatment of Patients With Newly Diagnosed High Risk Mantle Cell Lymphoma

NCT05471843Phase 1Active Not RecruitingPrimary

Study of Sonrotoclax (BGB-11417) Monotherapy in Participants With Relapsed or Refractory Mantle Cell Lymphoma

NCT06029309Phase 1RecruitingPrimary

Zanubrutinib and Tafasitamab in Mantle Cell Lymphoma

NCT07341191Phase 2RecruitingPrimary

Sonrotoclax Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma Planned for Standard of Care CAR-T Cell Therapy

NCT02446236Phase 1Active Not RecruitingPrimary

Dose Finding Study of Ibrutinib Plus Lenalidomide / Rituximab in Relapsed or Refractory Mantle Cell Lymphoma

NCT07168486Phase 1Enrolling By Invitation

CD19.20.22 CAR T-cells for Patients With Relapsed/Refractory B-Cell Lymphomas

NCT02558816Phase 1CompletedPrimary

A Trial of Obinutuzumab,GDC-0199 Plus Ibrutinib in Relapsed/Refractory Mantle Cell Lymphoma Patients

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