Key Insights

Highlights

Success Rate

60% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

11.8%

2 terminated out of 17 trials

Success Rate

60.0%

-26.5% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

100%

3 of 3 completed with results

Key Signals

3 with results60% success

Data Visualizations

Phase Distribution

15Total
P 1 (7)
P 2 (8)

Trial Status

Recruiting6
Completed3
Active Not Recruiting2
Unknown2
Terminated2
Withdrawn1

Trial Success Rate

60.0%

Benchmark: 86.5%

Based on 3 completed trials

Clinical Trials (17)

Showing 17 of 17 trials
NCT05985161Phase 2Recruiting

A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors

NCT04483778Phase 1Active Not Recruiting

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

NCT07549022Phase 1Not Yet RecruitingPrimary

Safety and Efficacy of BMS-986504 in Unresectable Malignant Peripheral Nerve Sheath Tumor

NCT04897321Phase 1Recruiting

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

NCT03141021RecruitingPrimary

Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors

NCT06515860Recruiting

Neurofibromatosis Type 1 Tumor Early Detection Study

NCT05245500Phase 1Recruiting

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

NCT03618381Phase 1Active Not Recruiting

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

NCT06277154Phase 2Recruiting

MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma

NCT02584647Phase 1Terminated

PLX3397 Plus Sirolimus in Unresectable Sarcoma and Malignant Peripheral Nerve Sheath Tumors

NCT03433183Phase 2CompletedPrimary

SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors

NCT03989596Phase 2Unknown

Hypofractionated Radiotherapy With Hyperthermia in Unresectable or Marginally Resectable Soft Tissue Sarcomas

NCT03651375Phase 2Unknown

Hypofractionated Radiotherapy With Sequential Chemotherapy in Marginally Resectable Soft Tissue Sarcomas of Extremities or Trunk Wall

NCT03880123Phase 1Withdrawn

Selinexor in Combination With Ixazomib for the Treatment of Advanced Sarcoma

NCT01661283Phase 2CompletedPrimary

SARC016: Study of Everolimus With Bevacizumab to Treat Refractory Malignant Peripheral Nerve Sheath Tumors

NCT00464620Phase 2Completed

Trial of Dasatinib in Advanced Sarcomas

NCT00427583Phase 2TerminatedPrimary

Imatinib Mesylate Treatment of Patients With Malignant Peripheral Nerve Sheath Tumors

Showing all 17 trials

Research Network

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