Malignant Glioma
156
13
30
91
Key Insights
Highlights
Success Rate
84% trial completion
Published Results
53 trials with published results (34%)
Research Maturity
91 completed trials (58% of total)
Clinical Risk Assessment
Based on trial outcomes
High Risk
Score: 59/100
10.9%
17 terminated out of 156 trials
84.3%
-2.3% vs benchmark
2%
3 trials in Phase 3/4
58%
53 of 91 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 91 completed trials
Clinical Trials (156)
A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)
Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial
Serial Advanced Magnetic Resonance Imaging Scan for Guidance of Personalized Adaptive Radiotherapy for High Grade Glioma
Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy
FPS-ZM1 With or Without Dexamethasone for Controlling Post Operative Cerebral Edema in Patients With Glioblastoma
Mind-Body Intervention in Glioma Couples
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)
Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma
Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations
CARv3-TEAM-E T Cells in Glioblastoma
Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma
Fitness and Nutrition in Glioma
Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery
D2C7 for Adult Patients With Recurrent Malignant Glioma
Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas
PEP-CMV in Recurrent MEdulloblastoma/Malignant Glioma
D2C7-IT With Atezolizumab for Recurrent Gliomas
Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults
Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG
Safety Study of the Repeated Opening of the Blood-brain Barrier With the SonoCloud® Device to Treat Malignant Brain Tumors in Pediatric Patients