Key Insights

Highlights

Success Rate

75% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

10.8%

4 terminated out of 37 trials

Success Rate

75.0%

-11.5% vs benchmark

Late-Stage Pipeline

5%

2 trials in Phase 3/4

Results Transparency

25%

3 of 12 completed with results

Key Signals

3 with results75% success

Data Visualizations

Phase Distribution

30Total
Not Applicable (5)
P 1 (12)
P 2 (11)
P 3 (2)

Trial Status

Completed12
Unknown10
Recruiting4
Terminated4
Withdrawn3
Active Not Recruiting2

Trial Success Rate

75.0%

Benchmark: 86.5%

Based on 12 completed trials

Clinical Trials (37)

Showing 20 of 20 trials
NCT02122185Phase 2Completed

Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

NCT07490626Not ApplicableNot Yet RecruitingPrimary

At-Home Paracentesis for Women With Cancer-Related Malignant Ascites (Paracentesis)

NCT07397819Phase 1RecruitingPrimary

Intraperitoneal Injection of Liposomal Irinotecan as Monotherapy or in Combination With Recombinant Mutant Human Tumor Necrosis Factor or Bevacizumab for the Treatment of Malignant Ascites Following Failure of Prior Standard Therapy

NCT06432296Phase 3Active Not RecruitingPrimary

Treatment of Malignant Ascites Caused by Advanced Epithelial Solid Tumors With M701 Bispecific Antibody

NCT06266091Phase 2CompletedPrimary

Treat Malignant Ascites Caused by Gastrointestinal or Ovarian Cancer With M701 Bispecific Antibody

NCT04501744Phase 1CompletedPrimary

A Study of M701 (EpCAM and CD3) in Malignant Ascites

NCT07007988Phase 1RecruitingPrimary

A Phase I Study of SIM0388 in Participants With Malignant Ascites.

NCT06016179Phase 1Recruiting

Tocilizumab Delivered Via Pleural and Peritoneal Catheters in Patients With Advanced Metastatic Cancer

NCT04985357Withdrawn

Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to Drugs

NCT04326946Active Not Recruiting

International Alfapump Cohort Study

NCT06433869Phase 2RecruitingPrimary

The Efficacy of Bevacizumab and Serplulimab Combined With Recombinant Mutant HumanTumor Necrosis Factor(rmhTNF-NC) in the Treatment of Malignant Ascites

NCT06200376Phase 1UnknownPrimary

A Clinical Study of Intraperitoneal T3011 Given as a Single Agent in Patients With Malignant Ascites Induced by Advanced Colorectal Cancer

NCT05477927Phase 1Unknown

Dual-targeting VEGFR1 and PD-L1 CAR-T for Cancers Patients With Pleural or Peritoneal Metastases

NCT05745233Not ApplicableEnrolling By InvitationPrimary

Intraperitoneal Immune Checkpoint Inhibitor for Malignant Ascites

NCT02724683UnknownPrimary

Symptomatic Ascites Drainage With a Patient-controlled Vascular Catheter.

NCT05501340Phase 1UnknownPrimary

PD-1 Inhibitor Intraperitoneal Perfusion Combined With PRaG Therapy for Malignant Ascites

NCT04051112Phase 1CompletedPrimary

Study With SCB-313 (Recombinant Human TRAIL-Trimer Fusion Protein) for Treatment of Malignant Ascites

NCT04032600Not ApplicableCompletedPrimary

Malignant Ascites in Ovarian Cancer: Impact of Total Paracentesis on Hemodynamics

NCT01532427Completed

ALFApump System Post Marketing Surveillance Registry

NCT04076566WithdrawnPrimary

Malignant Ascites Alfapump® Study

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