Malaria,Falciparum
87
4
12
50
Key Insights
Highlights
Success Rate
91% trial completion (above average)
Published Results
17 trials with published results (20%)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 40/100
5.7%
5 terminated out of 87 trials
90.9%
+4.4% vs benchmark
23%
20 trials in Phase 3/4
34%
17 of 50 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 50 completed trials
Clinical Trials (87)
Pharmacokinetics of Antimalarials in Breastfeeding Ugandan Mother-infant Pairs
Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of MMV371 LAI in Healthy Participants
A Phase 1 Study to Assess an Escalating Dose, Multi-prime Vaccination Schedule of R21/Matrix-M™
A Study to Assess the Experimental Malaria Vaccines R78C and RH5.1 With Matrix-M in Combination With R21/Matrix-M
A Study to Assess the Experimental Malaria Vaccines R78C and RH5.1 Combined With R21/Matrix-M (a "Multi-stage" Malaria Vaccine)
CHILD (Child Health and Infection With Low Density) Malaria
Safety, Pharmacokinetics, and Plasmodium Falciparum Transmission-reducing Activity of Monoclonal Antibody TB31F in Mali
Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics
Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. Falciparum
Safety and Immunogenicity of SUM-101 Malaria Vaccine in Children and Infants Living in Burkina Faso
Preventing Malaria in School Children to Protect the Whole Community in Rural Blantyre District, Malawi
An Observational Study to Assess Effectiveness and Safety of The R21/Matrix-M Malaria Vaccine
Safety, Immunogenicity and Efficacy of R21 Matrix-M in 5-17 Month Old Children in Nanoro, Burkina Faso
Understanding and Maximizing the Community Impact of Antimalarial Treatment (INDIE-SMC)
Safety and Immunogenicity of the Malaria Vaccine, R21/MatrixM, in Healthy Thai Adults
Pyronaridine in Healthy Adult Participants Infected With Blood Stage Malaria
A Study to Test Experimental Blood Stage Malaria Vaccine in Burkina Faso.
Safety and Efficacy of R0.6C Vaccine
A Study to Determine if New Types of Malaria Vaccines Are Safe, Effective and Lead to Immunity in Kenyan Adults
First-in-Human Study to Assess the Safety, Tolerability and Pharmacokinetics of MMV367