Key Insights

Highlights

Success Rate

91% trial completion (above average)

Published Results

17 trials with published results (20%)

Research Maturity

53 completed trials (61% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

5.7%

5 terminated out of 87 trials

Success Rate

91.4%

+4.8% vs benchmark

Late-Stage Pipeline

23%

20 trials in Phase 3/4

Results Transparency

32%

17 of 53 completed with results

Key Signals

17 with results91% success

Data Visualizations

Phase Distribution

72Total
Not Applicable (9)
Early P 1 (1)
P 1 (31)
P 2 (11)
P 3 (9)
P 4 (11)

Trial Status

Completed53
Unknown14
Active Not Recruiting6
Terminated5
Not Yet Recruiting4
Recruiting3

Trial Success Rate

91.4%

Benchmark: 86.6%

Based on 53 completed trials

Clinical Trials (87)

Showing 20 of 20 trials
NCT06618885Phase 1CompletedPrimary

Safety and Immunogenicity of SUM-101 Malaria Vaccine in Children and Infants Living in Burkina Faso

NCT06083688Phase 4CompletedPrimary

Preventing Malaria in School Children to Protect the Whole Community in Rural Blantyre District, Malawi

NCT05978037Phase 1Completed

A Study to Assess the Safety and Effectiveness of Two Experimental Malaria Vaccines

NCT05757167Phase 4Active Not RecruitingPrimary

Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics

NCT05676645Active Not RecruitingPrimary

Pharmacokinetics of Antimalarials in Breastfeeding Ugandan Mother-infant Pairs

NCT06558643Phase 1CompletedPrimary

Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of MMV371 LAI in Healthy Participants

NCT06320535Phase 1Active Not RecruitingPrimary

A Phase 1 Study to Assess an Escalating Dose, Multi-prime Vaccination Schedule of R21/Matrix-M™

NCT07183371Phase 2Active Not RecruitingPrimary

A Study to Assess the Experimental Malaria Vaccines R78C and RH5.1 With Matrix-M in Combination With R21/Matrix-M

NCT06958198Phase 1RecruitingPrimary

A Study to Assess the Experimental Malaria Vaccines R78C and RH5.1 Combined With R21/Matrix-M (a "Multi-stage" Malaria Vaccine)

NCT05567016Not ApplicableCompletedPrimary

CHILD (Child Health and Infection With Low Density) Malaria

NCT06413108Phase 1CompletedPrimary

Safety, Pharmacokinetics, and Plasmodium Falciparum Transmission-reducing Activity of Monoclonal Antibody TB31F in Mali

NCT05979207Phase 1Completed

Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. Falciparum

NCT07009847RecruitingPrimary

An Observational Study to Assess Effectiveness and Safety of The R21/Matrix-M Malaria Vaccine

NCT03896724Phase 1CompletedPrimary

Safety, Immunogenicity and Efficacy of R21 Matrix-M in 5-17 Month Old Children in Nanoro, Burkina Faso

NCT05878366Not ApplicableCompleted

Understanding and Maximizing the Community Impact of Antimalarial Treatment (INDIE-SMC)

NCT05252845Phase 2CompletedPrimary

Safety and Immunogenicity of the Malaria Vaccine, R21/MatrixM, in Healthy Thai Adults

NCT05287893Phase 1CompletedPrimary

Pyronaridine in Healthy Adult Participants Infected With Blood Stage Malaria

NCT05790889Phase 1RecruitingPrimary

A Study to Test Experimental Blood Stage Malaria Vaccine in Burkina Faso.

NCT04862416Phase 1Completed

Safety and Efficacy of R0.6C Vaccine

NCT03947190Phase 2TerminatedPrimary

A Study to Determine if New Types of Malaria Vaccines Are Safe, Effective and Lead to Immunity in Kenyan Adults

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