Key Insights

Highlights

Success Rate

86% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

7.1%

1 terminated out of 14 trials

Success Rate

85.7%

-0.8% vs benchmark

Late-Stage Pipeline

14%

2 trials in Phase 3/4

Results Transparency

33%

2 of 6 completed with results

Key Signals

2 with results86% success

Data Visualizations

Phase Distribution

10Total
Not Applicable (1)
P 1 (3)
P 2 (4)
P 3 (2)

Trial Status

Completed6
Active Not Recruiting3
Unknown3
Recruiting1
Terminated1

Trial Success Rate

85.7%

Benchmark: 86.5%

Based on 6 completed trials

Clinical Trials (14)

Showing 14 of 14 trials
NCT03827343Active Not RecruitingPrimary

Retrospective Study of Immunotherapy Related Toxicities and Factors Impacting Outcomes in Children and Adults With Cancer

NCT06339177Recruiting

Hemophagocytic Lymphohistiocytosis (HLH) Evaluation and Research of Clinical, ImmUnoLogic and TranscriptomE Study

NCT05001737Phase 3CompletedPrimary

Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE

NCT03721809Not ApplicableCompletedPrimary

Characterization of the Inflammatory Profile of Patients With Macrophage Activation Syndrome Secondary to Bacterial Sepsis

NCT05611710Phase 2Active Not Recruiting

Anakinra in Dengue With Hyperinflammation ( AnaDen )

NCT01966367Phase 1Active Not Recruiting

CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation

NCT06405152CompletedPrimary

Assessment of Macrophage Activation syndromE in STill's Disease

NCT02780583Phase 1TerminatedPrimary

Treatment of Macrophage Activation Syndrome (MAS) With Anakinra

NCT03311854Phase 2CompletedPrimary

A Study to Investigate the Safety and Efficacy of Emapalumab, an Anti-IFN-gamma mAb in Patients With Systemic Juvenile Idiopathic Arthritis (sJIA) or Adult-onset Still's Disease (AOSD) Developing Macrophage Activation Syndrome/Secondary HLH (MAS/sHLH)

NCT05137496Phase 3UnknownPrimary

Ruxolitinib and Methylprednisolone as a First-line Treatment for Macrophage Activation Syndrome

NCT04339712Phase 2Completed

Personalised Immunotherapy for SARS-CoV-2 (COVID-19) Associated With Organ Dysfunction

NCT03332225Phase 2Completed

A Trial of Validation and Restoration of Immune Dysfunction in Severe Infections and Sepsis

NCT02569463Phase 1UnknownPrimary

Low-dose IL-2 ( Interleukin-2) Treatment in Macrophage Activation Syndrome(MAS)

NCT01095146UnknownPrimary

New Candidate Criteria for Diagnosis of Macrophage Activation Syndrome

Showing all 14 trials

Research Network

Activity Timeline