Lynch Syndrome
104
30
44
28
Key Insights
Highlights
Success Rate
90% trial completion (above average)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 50/100
2.9%
3 terminated out of 104 trials
90.3%
+3.8% vs benchmark
5%
5 trials in Phase 3/4
18%
5 of 28 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 28 completed trials
Clinical Trials (104)
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair
Study Aiming to Test Whether Non-invasive Liquid Biopsies Can Safely Reduce Invasive Surveillance Methods in Lynch Syndrome
Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome
Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma
Identifying and Caring for Individuals With Inherited Cancer Syndrome
Patient Centered Clinical Decision Support for Hereditary Cancer Syndromes
Integrated Cancer Repository for Cancer Research
Overcoming Barriers to Uptake of Cascade Screening
Determining the Prevalence of Muir-Torre Syndrome in Patients With Lynch Syndrome
Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome
Familial Investigations of Childhood Cancer Predisposition
Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI Study
Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome
Colonoscopy Check-up in People With Lynch Syndrome
A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome
Preventive Dendritic Cell Vaccination for Lynch Syndrome Carriers
Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients
Periodontal Disease in Patients With Lynch Syndrome
A Web-Based Program (Kindred) to Improve the Understanding of Genetic Cancer Risk and Cancer Genetic Testing in African American Families
Cascade Genetic Testing for Hereditary Breast/Ovarian Cancer and Lynch Syndrome in Switzerland