Lynch Syndrome
102
27
41
28
Key Insights
Highlights
Success Rate
90% trial completion (above average)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 50/100
2.9%
3 terminated out of 102 trials
90.3%
+3.8% vs benchmark
4%
4 trials in Phase 3/4
14%
4 of 28 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 28 completed trials
Clinical Trials (102)
Preventive Dendritic Cell Vaccination for Lynch Syndrome
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair
Integrated Cancer Repository for Cancer Research
Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients
Evaluation of Capsule Colonoscopy in Patients With Lynch Syndrome
A Web-Based Program (Kindred) to Improve the Understanding of Genetic Cancer Risk and Cancer Genetic Testing in African American Families
Overcoming Barriers to Uptake of Cascade Screening
Lynch Syndrome X-Talk of Enteral Mucosa With Immune System
Familial Investigations of Childhood Cancer Predisposition
Videocapsule Endoscopy in Lynch Syndrome
The Yield of Artificial Intelligence (GI Genius) in Lynch Syndrome - A Randomized Tandem-colonoscopy Trial
Weight Management and Health Behavior Intervention in Lowering Cancer Risk for BRCA Positive and Lynch Syndrome Families
Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma
Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome
First in Human Pilot Study to Assess the Safety and Efficacy of Dendritic Cells Loaded With Frameshift Derived Neopeptides for the Prevention of Cancer in of Lynch Syndrome Carriers
Pediatric Reporting of Adult-Onset Genomic Results
Scalable Communication Modalities for Returning Genetic Research Results
The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics
Small Bowel Capsule Endoscopy in Lynch Syndrome
Feasibility Study: IGNITE-TX (Identifying Individuals for Genetic Testing & Treatment) Intervention