Lynch Syndrome
105
30
43
30
Key Insights
Highlights
Success Rate
91% trial completion (above average)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 50/100
2.9%
3 terminated out of 105 trials
90.9%
+4.3% vs benchmark
5%
5 trials in Phase 3/4
17%
5 of 30 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 30 completed trials
Clinical Trials (105)
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair
Liquid Biopsy Evaluation and Repository Development at Princess Margaret
Liquid Biopsy Biomarkers for Endoscopic Surveillance in Lynch Syndrome
Feasibility Study: IGNITE-TX (Identifying Individuals for Genetic Testing & Treatment) Intervention
Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members
The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics
Assessing Uterine Cancer Risk in Lynch Syndrome Carriers Using Vaginal Self-sampling and a Health Questionnaire
Overcoming Barriers to Uptake of Cascade Screening
Pancreatic Cancer Early Detection Program
Preventive Dendritic Cell Vaccination for Lynch Syndrome
Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients
Study Aiming to Test Whether Non-invasive Liquid Biopsies Can Safely Reduce Invasive Surveillance Methods in Lynch Syndrome
Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome
Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma
Identifying and Caring for Individuals With Inherited Cancer Syndrome
Patient Centered Clinical Decision Support for Hereditary Cancer Syndromes
Integrated Cancer Repository for Cancer Research
Determining the Prevalence of Muir-Torre Syndrome in Patients With Lynch Syndrome
Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome
Familial Investigations of Childhood Cancer Predisposition