Key Insights

Highlights

Success Rate

91% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

2.9%

3 terminated out of 105 trials

Success Rate

90.9%

+4.3% vs benchmark

Late-Stage Pipeline

5%

5 trials in Phase 3/4

Results Transparency

17%

5 of 30 completed with results

Key Signals

5 with results91% success

Data Visualizations

Phase Distribution

59Total
Not Applicable (39)
Early P 1 (4)
P 1 (6)
P 2 (5)
P 3 (5)

Trial Status

Completed30
Recruiting30
Active Not Recruiting13
Not Yet Recruiting12
Unknown12
Withdrawn3

Trial Success Rate

90.9%

Benchmark: 86.6%

Based on 30 completed trials

Clinical Trials (105)

Showing 20 of 20 trials
NCT02912559Phase 3Active Not Recruiting

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

NCT03702309Recruiting

Liquid Biopsy Evaluation and Repository Development at Princess Margaret

NCT07838246CompletedPrimary

Liquid Biopsy Biomarkers for Endoscopic Surveillance in Lynch Syndrome

NCT05677048Not ApplicableActive Not Recruiting

Feasibility Study: IGNITE-TX (Identifying Individuals for Genetic Testing & Treatment) Intervention

NCT02194387Not ApplicableActive Not Recruiting

Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members

NCT05692596Active Not Recruiting

The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics

NCT07194551Not ApplicableRecruiting

Assessing Uterine Cancer Risk in Lynch Syndrome Carriers Using Vaginal Self-sampling and a Health Questionnaire

NCT07304063Not ApplicableNot Yet RecruitingPrimary

Overcoming Barriers to Uptake of Cascade Screening

NCT02206360Completed

Pancreatic Cancer Early Detection Program

NCT07412197Phase 1Not Yet RecruitingPrimary

Preventive Dendritic Cell Vaccination for Lynch Syndrome

NCT05410977Recruiting

Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients

NCT07360834Not ApplicableNot Yet RecruitingPrimary

Study Aiming to Test Whether Non-invasive Liquid Biopsies Can Safely Reduce Invasive Surveillance Methods in Lynch Syndrome

NCT07106359Not ApplicableRecruiting

Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome

NCT02359565Phase 1Active Not Recruiting

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma

NCT04494945Not ApplicableRecruiting

Identifying and Caring for Individuals With Inherited Cancer Syndrome

NCT06914726Not ApplicableEnrolling By Invitation

Patient Centered Clinical Decision Support for Hereditary Cancer Syndromes

NCT02012699Recruiting

Integrated Cancer Repository for Cancer Research

NCT07201012Not ApplicableRecruiting

Determining the Prevalence of Muir-Torre Syndrome in Patients With Lynch Syndrome

NCT05419011Phase 2Active Not Recruiting

Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome

NCT03050268Recruiting

Familial Investigations of Childhood Cancer Predisposition

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Research Network

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