Key Insights

Highlights

Success Rate

92% trial completion (above average)

Published Results

13 trials with published results (25%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

3.9%

2 terminated out of 51 trials

Success Rate

92.0%

+5.5% vs benchmark

Late-Stage Pipeline

4%

2 trials in Phase 3/4

Results Transparency

57%

13 of 23 completed with results

Key Signals

13 with results92% success

Data Visualizations

Phase Distribution

48Total
Not Applicable (3)
Early P 1 (1)
P 1 (18)
P 2 (24)
P 3 (2)

Trial Status

Completed23
Recruiting16
Active Not Recruiting6
Withdrawn2
Terminated2
Unknown1

Trial Success Rate

92.0%

Benchmark: 86.5%

Based on 23 completed trials

Clinical Trials (51)

Showing 20 of 20 trials
NCT04799275Phase 2Active Not Recruiting

Testing CC-486 (Oral Azacitidine) Plus the Standard Drug Therapy in Patients 75 Years or Older With Newly Diagnosed Diffuse Large B Cell Lymphoma

NCT07249905Phase 1Recruiting

Dose Escalation and Dose Expansion Study of MDX2003 in Patients With Different Types of Lymphoma

NCT00923507Recruiting

Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma (SMZL)

NCT04840602Phase 2RecruitingPrimary

Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

NCT07387471Phase 2Recruiting

Study to Assess Change in Disease Activity of Oral Venetoclax in Adult Participants With Recurring Relapsed or Refractory (R/R) Waldenström Macroglobulinemia (WM)/Lymphoplasmacytic Lymphoma (LPL)

NCT04488354Phase 1Completed

Long-term Follow-up Study for Patients Treated With CLBR001 CAR-T

NCT02952508Phase 2Active Not Recruiting

Study of Iopofosine I-131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) With Expansion in Waldenstrom

NCT01962636Not ApplicableRecruiting

Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases

NCT02339922Phase 2Active Not Recruiting

Ixazomib Citrate and Rituximab in Treating Patients With Indolent B-cell Non-Hodgkin Lymphoma

NCT04195633Phase 2Recruiting

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies

NCT05544019Phase 1Recruiting

Study of SGR-1505 in Mature B-Cell Neoplasms

NCT04883437Phase 2Recruiting

Acalabrutinib and Obinutuzumab for the Treatment of Previously Untreated Follicular Lymphoma or Other Indolent Non-Hodgkin Lymphomas

NCT04545762Phase 1Recruiting

Anti-CD19 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma

NCT03674411Phase 2Active Not Recruiting

Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy

NCT03884998Phase 1Active Not Recruiting

Copanlisib and Nivolumab in Treating Patients With Richter's Transformation or Transformed Indolent Non-Hodgkin Lymphoma

NCT04191187Phase 2Completed

Reduced Intensity Flu/Mel/TBI Conditioning for HAPLO HCT Patients With Hematologic Malignancies

NCT06986174Phase 2Recruiting

A Phase 2 Study to Evaluate the Safety and Efficacy of Pacritinib in Relapsed or Refractory Waldenström Macroglobulinemia

NCT07173790Enrolling By Invitation

Watch and Wait or Worry and Wait in Indolent Lymphoma

NCT07231952Phase 2Recruiting

A Study of Pirtobrutinib, Venetoclax, and Rituximab in People With Waldenström's Macroglobulinemia (WM)/Lymphoplasmacytic Lymphoma (LPL)

NCT01209871Phase 1Active Not RecruitingPrimary

Vaccine Therapy in Treating Patients With Lymphoplasmacytic Lymphoma

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