Key Insights

Highlights

No notable highlights available yet

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 65/100

Termination Rate

9.5%

2 terminated out of 21 trials

Success Rate

0.0%

-86.5% vs benchmark

Late-Stage Pipeline

14%

3 trials in Phase 3/4

Results Transparency

0%

2 of 0 completed with results

Key Signals

2 with results0

Data Visualizations

Phase Distribution

20Total
P 1 (12)
P 2 (5)
P 3 (3)

Trial Status

Active Not Recruiting12
Recruiting6
Terminated2
Withdrawn1

Clinical Trials (21)

Showing 20 of 20 trials
NCT03244384Phase 3Active Not Recruiting

Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer

NCT06524544Phase 3RecruitingPrimary

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitean-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

NCT03854474Phase 1Active Not RecruitingPrimary

Testing the Addition of Tazemetostat to the Immunotherapy Drug, Pembrolizumab (MK-3475), in Advanced Urothelial Carcinoma

NCT07048457Phase 2RecruitingPrimary

Consolidative Local Therapy (CLT) in Oligo-metastatic Urothelial Carcinoma

NCT06265285Phase 2Recruiting

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

NCT04963153Phase 1Active Not Recruiting

Testing Combination Erdafitinib and Enfortumab Vedotin in Metastatic Bladder Cancer After Treatment With Chemotherapy and Immunotherapy

NCT05154994Phase 1Active Not Recruiting

Tremelimumab + Durvalumab(MEDI4736)+ Belinostat in Urothelial Carcinoma

NCT04878029Phase 1Recruiting

Cabozantinib in Combination With Enfortumab Vedotin for Locally Advanced or Metastatic Urothelial Cancer

NCT04953104Phase 2Active Not Recruiting

ARID1A and/or KDM6A Mutation and CXCL13 Expression

NCT07492628Phase 1Recruiting

Dual-Target Nectin-4/HER2 CAR-NK Cells in Advanced Urothelial Carcinoma

NCT04637594Phase 3Active Not Recruiting

Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy

NCT05923190Phase 2Active Not Recruiting

Enfortumab Vedotin Schedule De-escalation in Metastatic Urothelial Carcinoma

NCT04007744Phase 1Active Not Recruiting

Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

NCT07217496Phase 1Withdrawn

N-803 in Combination With Pembrolizumab and Enfortumab Vedotin for Treatment of Urothelial Cancer

NCT05269381Phase 1Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

NCT04848519Phase 2Active Not Recruiting

Immune Checkpoint Inhibitors With or Without Propranolol Hydrochloride In Patients With Urothelial Carcinoma

NCT06483334Phase 1Active Not Recruiting

A Study of Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Plus Enfortumab Vedotin (EV) With and Without Pembrolizumab in Advanced Urothelial Carcinoma (MK-3475-04C/KEYMAKER-U04)

NCT04856189Phase 1Terminated

Selinexor and Pembrolizumab for the Treatment of Cisplatin-Ineligible or Cisplatin-Refractory Locally Advanced or Metastatic Urothelial Carcinoma

NCT05544552Phase 1Active Not RecruitingPrimary

Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations

NCT00365157Phase 1Active Not Recruiting

Eribulin Mesylate in Treating Patients With Locally Advanced or Metastatic Cancer of the Urothelium and Kidney Dysfunction

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