Key Insights

Highlights

Success Rate

71% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

7.4%

2 terminated out of 27 trials

Success Rate

71.4%

-15.1% vs benchmark

Late-Stage Pipeline

7%

2 trials in Phase 3/4

Results Transparency

20%

1 of 5 completed with results

Key Signals

1 with results71% success

Data Visualizations

Phase Distribution

21Total
Not Applicable (5)
Early P 1 (3)
P 1 (3)
P 2 (8)
P 3 (2)

Trial Status

Recruiting7
Completed5
Active Not Recruiting5
Not Yet Recruiting5
Terminated2
Unknown1

Trial Success Rate

71.4%

Benchmark: 86.5%

Based on 5 completed trials

Clinical Trials (27)

Showing 20 of 20 trials
NCT05245786Early Phase 1Active Not RecruitingPrimary

An Investigational Scan (64Cu-Labeled M5A Antibody) in Combination With SOC Chemotherapy and Radiotherapy in Locally Advanced Rectal Cancer

NCT05722288Phase 2Active Not Recruiting

Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers

NCT07580027Not ApplicableNot Yet RecruitingPrimary

Preoperative, Adaptive Radiotherapy Concomitant to Chemotherapy for Rectal Adenocarcinoma (Adaptive Rectal Cancer Trial 02)

NCT04703101Phase 1RecruitingPrimary

Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer

NCT07472868Phase 3Not Yet RecruitingPrimary

Neoadjuvant FOLFOXIRI and Chemoradiotherapy Versus Neoadjuvant CAPOX/FOLFOX and Chemoradiotherapy Followed by Surgery or a Watch-and-Wait Approach in High Risk Locally Advanced Rectal Cancer

NCT06292975Not ApplicableWithdrawnPrimary

Exercise for Improving Radiotherapy Efficacy in Rectal Cancer

NCT05731726Phase 2Recruiting

Serplulimab Combined With CAPEOX + Celecoxib as Neoadjuvant Treatment for Locally Advanced Rectal Cancer

NCT07372300Phase 3RecruitingPrimary

Modulated Electro-Hyperthermia in Combination With Multimodal Therapy for Locally Advanced Rectal Cancer

NCT06312982Phase 2RecruitingPrimary

A Series of Neoadjuvant Chemoradiotherapy Combined With Immunotherapy for Locally Advanced Rectal Cancer

NCT05876026Completed

MRI T1 Relaxation Time in Rectal Cancer

NCT07038122Not ApplicableActive Not RecruitingPrimary

Reducing the Resection Range After Neoadjuvant Therapy for Locally Advanced Upper Rectal and Rectosigmoid Junction Cancers

NCT05524012Active Not RecruitingPrimary

Longitudinal Multimodal Response Assessment During Neoadjuvant Treatment of Rectal Cancer

NCT05610163Phase 2Active Not RecruitingPrimary

Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation

NCT06314750CompletedPrimary

Deep Learning Based MRI Radiomics in Predicting the Clinical Risk of Locally Advanced Rectal Cancer

NCT05591534Phase 2SuspendedPrimary

Endorectal Brachytherapy for Rectal Cancer

NCT04406857Phase 1TerminatedPrimary

Testing the Addition of a Radiation Sensitizing Drug, IPdR, to the Usual Chemotherapy Treatment (Capecitabine) During Radiation Therapy for Rectal Cancer

NCT06843655Not Yet RecruitingPrimary

Radiological Markers in Locally Advanced Rectal Cancer

NCT05792735Phase 2CompletedPrimary

Neoadjuvant Cadonilimab Plus Chemotherapy Following Short-Course Radiotherapy in Locally Advanced Rectal Cancer

NCT06276686Early Phase 1RecruitingPrimary

Exercise for Improving Long-course Chemoradiotherapy Efficacy in People With Locally Advanced Rectal Cancer

NCT05601505Phase 2RecruitingPrimary

Circulating Tumor DNA-guided Neoadjuvant Treatment Strategy for Locally Advanced Rectal Cancer

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