Key Insights

Highlights

Success Rate

86% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

5.3%

1 terminated out of 19 trials

Success Rate

85.7%

-0.8% vs benchmark

Late-Stage Pipeline

5%

1 trials in Phase 3/4

Results Transparency

17%

1 of 6 completed with results

Key Signals

1 with results86% success

Data Visualizations

Phase Distribution

15Total
Not Applicable (7)
P 1 (6)
P 2 (1)
P 3 (1)

Trial Status

Completed6
Recruiting5
Unknown5
Withdrawn1
Not Yet Recruiting1
Terminated1

Trial Success Rate

85.7%

Benchmark: 86.5%

Based on 6 completed trials

Clinical Trials (19)

Showing 19 of 19 trials
NCT07636590RecruitingPrimary

Multi-Center, Prospective, Non-Interventional Study in Subjects With Limbal Stem Cell Deficiency

NCT00845117Not ApplicableCompletedPrimary

Cultivated Stem Cell Transplantation for the Treatment of Limbal Stem Cell Deficiency

NCT06452316Phase 1RecruitingPrimary

Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Limbal Stem Cell Deficiency

NCT07119580Recruiting

Association Between Limbal Function and Tear Proteomics in Chronic Ocular Diseases: Focusing on Glaucoma

NCT01756365Not ApplicableRecruitingPrimary

Autologous Cultured Corneal Epithelium (CECA) for the Treatment of Limbal Stem Cell Deficiency

NCT02592330Phase 1CompletedPrimary

Limbal Stem Cell Deficiency (LSCD) Treatment With Cultivated Stem Cell (CALEC) Graft

NCT02318485Phase 2CompletedPrimary

Limbal Epithelial Stem Cell Transplantation: a Phase II Multicenter Trial

NCT06265298Not ApplicableRecruitingPrimary

Implementation of a Protocol for the Transdifferentiation of Buccal Mucosal Epithelium Into Corneal Epithelium

NCT06412718Not Yet Recruiting

Validation of Human Drugs Target of Repurposed Drugs and Novel Therapies

NCT03549299Phase 1UnknownPrimary

Allogeneic ABCB5-positive Limbal Stem Cells for Treatment of LSCD

NCT03943797Phase 1UnknownPrimary

Cultivated Autologous Oral Mucosal Epithelial Transplantation

NCT03217435Not ApplicableCompletedPrimary

Corneal Epithelial Allograft From Living-related Donor for LSCD

NCT03217487Not ApplicableUnknownPrimary

Corneal Epithelial Autograft for LSCD

NCT02568527Not ApplicableCompletedPrimary

Biodegradable Synthetic Scaffold as a Substitute for hAM in Limbal Epithelial Cells Transplant in LSCD Patients

NCT02579993Not ApplicableTerminatedPrimary

ABCB5 as a Prognostic Marker in Survival of Cultivated Limbal Stem Cell Transplantation

NCT03015779Phase 1UnknownPrimary

Transplantation of Autologous Oral Mucosal Epithelial Stem Cell Sheet for Treating Limbal Stem Cell Deficiency Disease

NCT02149732UnknownPrimary

Clinical Trial on the Effect of Autologous Oral Mucosal Epithelial Sheet Transplantation

NCT01489501Phase 3WithdrawnPrimary

Multicenter Study of CAOMECS Transplantation to Patients With Total Limbal Stem Cell Deficiency

NCT00736307Phase 1CompletedPrimary

Autologous Transplantation of Cultivated Limbal Stem Cells on Amniotic Membrane in Limbal Stem Cell Deficiency (LSD) Patients

Showing all 19 trials

Research Network

Activity Timeline