Key Insights

Highlights

Success Rate

71% trial completion

Published Results

50 trials with published results (24%)

Research Maturity

91 completed trials (44% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

18.4%

38 terminated out of 207 trials

Success Rate

70.5%

-16.0% vs benchmark

Late-Stage Pipeline

8%

16 trials in Phase 3/4

Results Transparency

55%

50 of 91 completed with results

Key Signals

50 with results71% success38 terminated

Data Visualizations

Phase Distribution

180Total
Not Applicable (16)
Early P 1 (3)
P 1 (95)
P 2 (50)
P 3 (14)
P 4 (2)

Trial Status

Completed91
Terminated38
Unknown27
Recruiting25
Active Not Recruiting12
Not Yet Recruiting6

Trial Success Rate

70.5%

Benchmark: 86.5%

Based on 91 completed trials

Clinical Trials (207)

Showing 20 of 20 trials
NCT05413018Phase 2Active Not RecruitingPrimary

An Efficacy and Safety Study of Oral Azacitidine (CC-486) as Maintenance Therapy in Chinese Participants With Acute Myeloid Leukemia in Complete Remission

NCT06424340Phase 1RecruitingPrimary

MB-dNPM1-TCR.1 in Relapsed/Refractory AML

NCT07216443Phase 2RecruitingPrimary

Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

NCT06001788Phase 1Recruiting

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT06618001Phase 1RecruitingPrimary

A Study of JNJ-89853413 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms

NCT05453903Phase 1Active Not RecruitingPrimary

A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies

NCT06651229Phase 1RecruitingPrimary

A Study of JNJ-90189892 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms

NCT06852222Phase 3RecruitingPrimary

A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

NCT06788509Phase 1Enrolling By InvitationPrimary

A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring

NCT07469592Not ApplicableNot Yet Recruiting

eHealth Mindfulness-based Music Therapy Intervention for Patients Undergoing Stem Cell Transplantation

NCT04940468Not ApplicableTerminated

High- Fiber/ Low-fat Diet for Prevention of Recurrent Clostridioides Difficile Infection in Oncology

NCT04988555Phase 1RecruitingPrimary

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

NCT05565105Phase 2Not Yet RecruitingPrimary

CD34+ Transplants for Leukemia and Lymphoma

NCT02677922Phase 1Active Not RecruitingPrimary

A Study to Assess the Safety and Efficacy of Two Combinations of Isocitrate Dehydrogenase (IDH) Mutant Targeted Therapies Plus Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) Harboring IDH Mutations Who Are Not Candidates to Receive Intensive Induction Chemotherapy

NCT05968963Not ApplicableActive Not Recruiting

Electronic Health Mindfulness-based Music Therapy Intervention for Patients Undergoing Allogeneic Stem Cell Transplantation

NCT06580106RecruitingPrimary

Toxicity Genetic Determinants and Response to Azacitidine and Venetoclax in AML

NCT03926624Phase 3TerminatedPrimary

Trial of DFP-10917 vs Non-Intensive or Intensive Reinduction for AML Patients in 2nd/3rd/4th Salvage

NCT06345027Phase 1Not Yet RecruitingPrimary

Chimeric Antigen Receptor Treatment Targeting CD70 (SEVENTY)

NCT07269067Not Yet RecruitingPrimary

Automated vs Manual Flow-cytometry Gating for Measurable Residual Disease in Acute Myeloid Leukaemia (DUALFLOW)

NCT03173248Phase 3Active Not Recruiting

Study of AG-120 (Ivosidenib) vs. Placebo in Combination With Azacitidine in Participants With Previously Untreated Acute Myeloid Leukemia With an IDH1 Mutation

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