Key Insights

Highlights

Success Rate

72% trial completion

Published Results

53 trials with published results (25%)

Research Maturity

95 completed trials (45% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

17.7%

37 terminated out of 209 trials

Success Rate

72.0%

-14.6% vs benchmark

Late-Stage Pipeline

8%

16 trials in Phase 3/4

Results Transparency

56%

53 of 95 completed with results

Key Signals

53 with results72% success37 terminated

Data Visualizations

Phase Distribution

182Total
Not Applicable (16)
Early P 1 (3)
P 1 (96)
P 2 (51)
P 3 (14)
P 4 (2)

Trial Status

Completed95
Terminated37
Unknown26
Recruiting24
Active Not Recruiting13
Not Yet Recruiting6

Trial Success Rate

72.0%

Benchmark: 86.6%

Based on 95 completed trials

Clinical Trials (209)

Showing 20 of 20 trials
NCT06651229Phase 1Active Not RecruitingPrimary

A Study of JNJ-90189892 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms

NCT06788509Phase 1Enrolling By InvitationPrimary

A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring

NCT06852222Phase 3RecruitingPrimary

A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

NCT06618001Phase 1Active Not RecruitingPrimary

A Study of JNJ-89853413 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms

NCT05453903Phase 1Active Not RecruitingPrimary

A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies

NCT06345027Phase 1RecruitingPrimary

Chimeric Antigen Receptor Treatment Targeting CD70 (SEVENTY)

NCT06956755Recruiting

Registry of Myelodysplastic Syndromes and Therapy-related Acute Myeloid Leukemia

NCT04940468Not ApplicableCompleted

High- Fiber/ Low-fat Diet for Prevention of Recurrent Clostridioides Difficile Infection in Oncology

NCT05599360Phase 2Active Not RecruitingPrimary

Vyxeos for Induction of Low- or Intermediate-risk.

NCT06001788Phase 1Recruiting

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT07469592Not ApplicableRecruiting

eHealth Mindfulness-based Music Therapy Intervention for Patients Undergoing Stem Cell Transplantation

NCT05968963Not ApplicableCompleted

Electronic Health Mindfulness-based Music Therapy Intervention for Patients Undergoing Allogeneic Stem Cell Transplantation

NCT06580106RecruitingPrimary

Toxicity Genetic Determinants and Response to Azacitidine and Venetoclax in AML

NCT07726576Phase 1Not Yet RecruitingPrimary

Venetoclax in Association With 3+7 and Midostaurin in FLT3-mutated Acute Myeloid Leukemia

NCT07686107Phase 2Not Yet RecruitingPrimary

Trial of Revumenib Plus FLA Chemotherapy for Children With Relapsed or Refractory NUP98-rearranged AML."

NCT05945849Phase 1RecruitingPrimary

CD33KO-HSPC Infusion Followed by CART-33 Infusion(s) for Refractory/Relapsed AML

NCT07216443Phase 2RecruitingPrimary

Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

NCT05270200Phase 1RecruitingPrimary

Single Arm Study of Post-transplant Azacitidine and Chidamide for Prevention of Acute Myelogenous Leukemia Relapse

NCT03173248Phase 3Active Not Recruiting

Study of AG-120 (Ivosidenib) vs. Placebo in Combination With Azacitidine in Participants With Previously Untreated Acute Myeloid Leukemia With an IDH1 Mutation

NCT04090736Phase 3Active Not RecruitingPrimary

Study to Compare Azacitidine Plus Pevonedistat Versus Azacitidine in Patients With Acute Myeloid Leukemia Not Eligible for Standard Chemotherapy

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Research Network

Activity Timeline