Key Insights

Highlights

Success Rate

71% trial completion

Published Results

50 trials with published results (24%)

Research Maturity

93 completed trials (44% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

18.2%

38 terminated out of 209 trials

Success Rate

71.0%

-15.6% vs benchmark

Late-Stage Pipeline

8%

16 trials in Phase 3/4

Results Transparency

54%

50 of 93 completed with results

Key Signals

50 with results71% success38 terminated

Data Visualizations

Phase Distribution

182Total
Not Applicable (16)
Early P 1 (3)
P 1 (96)
P 2 (51)
P 3 (14)
P 4 (2)

Trial Status

Completed93
Terminated38
Unknown26
Recruiting23
Active Not Recruiting13
Not Yet Recruiting8

Trial Success Rate

71.0%

Benchmark: 86.6%

Based on 93 completed trials

Clinical Trials (209)

Showing 20 of 20 trials
NCT06618001Phase 1Active Not RecruitingPrimary

A Study of JNJ-89853413 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms

NCT06852222Phase 3RecruitingPrimary

A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

NCT06788509Phase 1Enrolling By InvitationPrimary

A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring

NCT06580106RecruitingPrimary

Toxicity Genetic Determinants and Response to Azacitidine and Venetoclax in AML

NCT07726576Phase 1Not Yet RecruitingPrimary

Venetoclax in Association With 3+7 and Midostaurin in FLT3-mutated Acute Myeloid Leukemia

NCT07686107Phase 2Not Yet RecruitingPrimary

Trial of Revumenib Plus FLA Chemotherapy for Children With Relapsed or Refractory NUP98-rearranged AML."

NCT05945849Phase 1RecruitingPrimary

CD33KO-HSPC Infusion Followed by CART-33 Infusion(s) for Refractory/Relapsed AML

NCT07216443Phase 2RecruitingPrimary

Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

NCT05270200Phase 1RecruitingPrimary

Single Arm Study of Post-transplant Azacitidine and Chidamide for Prevention of Acute Myelogenous Leukemia Relapse

NCT05453903Phase 1Active Not RecruitingPrimary

A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies

NCT06651229Phase 1RecruitingPrimary

A Study of JNJ-90189892 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms

NCT03173248Phase 3Active Not Recruiting

Study of AG-120 (Ivosidenib) vs. Placebo in Combination With Azacitidine in Participants With Previously Untreated Acute Myeloid Leukemia With an IDH1 Mutation

NCT04090736Phase 3Active Not RecruitingPrimary

Study to Compare Azacitidine Plus Pevonedistat Versus Azacitidine in Patients With Acute Myeloid Leukemia Not Eligible for Standard Chemotherapy

NCT05774990CompletedPrimary

Study Protocol: Study on Incidence and Risk Factors of Mold Infections in Children During Leukemia Treatment

NCT04687761Phase 1CompletedPrimary

Clinical Trial to Assess the Safety and Tolerability of the Combination of Low-dose Cytarabine or Azacitidine Plus Venetoclax and Quizartinib in Newly Diagnosed AML Patients Aged Equal or More Than 60 Years Old

NCT04150887Phase 1Active Not RecruitingPrimary

Cusatuzumab in Combination With Background Therapy for the Treatment of Participants With Acute Myeloid Leukemia

NCT06384261Phase 2Active Not RecruitingPrimary

A Study Comparing Venetoclax and Azacitidine Plus Cusatuzumab to Venetoclax and Azacitidine in Newly Diagnosed AML Ineligible for Intensive Therapy

NCT05413018Phase 2Active Not RecruitingPrimary

An Efficacy and Safety Study of Oral Azacitidine (CC-486) as Maintenance Therapy in Chinese Participants With Acute Myeloid Leukemia in Complete Remission

NCT06424340Phase 1RecruitingPrimary

MB-dNPM1-TCR.1 in Relapsed/Refractory AML

NCT06001788Phase 1Recruiting

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Scroll to load more

Research Network

Activity Timeline