Key Insights

Highlights

Success Rate

73% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 54/100

Termination Rate

24.0%

6 terminated out of 25 trials

Success Rate

72.7%

-13.8% vs benchmark

Late-Stage Pipeline

36%

9 trials in Phase 3/4

Results Transparency

44%

7 of 16 completed with results

Key Signals

7 with results73% success

Data Visualizations

Phase Distribution

24Total
Not Applicable (1)
P 1 (5)
P 2 (9)
P 3 (8)
P 4 (1)

Trial Status

Completed16
Terminated6
Unknown3

Trial Success Rate

72.7%

Benchmark: 86.5%

Based on 16 completed trials

Clinical Trials (25)

Showing 20 of 20 trials
NCT02158858Phase 1Completed

A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies

NCT02140242Phase 3CompletedPrimary

Comparison Between Two Dose Levels of Daunorubicin and Between One vs. Two Induction Cycles for Adult Patients With AML

NCT01756118Phase 1Completed

A Phase I, Dose-finding Study of BEZ235 in Adult Patients With Relapsed or Refractory Acute Leukemia

NCT00406393Phase 3CompletedPrimary

Sirolimus/Tacrolimus Versus Tacrolimus/Methotrexate for Preventing Graft-Versus-Host Disease (GVHD) (BMT CTN 0402)

NCT01339910Phase 3TerminatedPrimary

Reduced Intensity Regimen vs Myeloablative Regimen for Myeloid Leukemia or Myelodysplastic Syndrome (BMT CTN 0901)

NCT00201240Phase 2CompletedPrimary

Acute Myeloid Leukemia T Cell Depletion to Improve Transplants in Adults With Acute Myeloid Leukemia (BMT CTN 0303)

NCT00067002Phase 2Completed

Randomized Double Cord Blood Transplant Study

NCT00048100Phase 1TerminatedPrimary

Anti-Leukemic Dendritic Cell Activated Donor Lymphocytes

NCT00449319Not ApplicableUnknownPrimary

AML Treatment in Untreated Adult Patients

NCT00044486Phase 3CompletedPrimary

Prophylaxis Trial of Posaconazole Versus Standard Azole Therapy for Neutropenic Patients (Study P01899)

NCT00000589Phase 3Completed

Trial to Reduce Alloimmunization to Platelets (TRAP)

NCT02895412Phase 1UnknownPrimary

Infection and Tumour Antigen Cellular Therapy

NCT01050946Phase 2Terminated

Hematopoietic Stem Cell Transplantation (HSCT) Using CD34 Selected Mismatched Related Donor and One Umbilical Cord Unit

NCT00393380Phase 2Terminated

Study of Parathyroid Hormone Following Sequential Cord Blood Transplantation From an Unrelated Donor

NCT00136084Phase 3CompletedPrimary

Treatment of Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplasia

NCT01723657Phase 2CompletedPrimary

Risk Adapted Treatment for Primary Acute Myeloid Leukemia (AML)

NCT01716793Phase 2CompletedPrimary

Risk-adapted Therapy for Adult Acute Myeloid Leukemia.

NCT00286845CompletedPrimary

Use of the MiCK Assay for Apoptosis in AML

NCT00446303Phase 2TerminatedPrimary

A Phase II Study of Maintenance With Azacitidine in MDS Patients

NCT00251368Phase 1CompletedPrimary

Multicenter Study of 9-Aminocamptothecin (9-AC) in Patients With Refractory Leukemia

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Research Network

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