Key Insights

Highlights

Success Rate

74% trial completion

Published Results

23 trials with published results (29%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

12.7%

10 terminated out of 79 trials

Success Rate

73.7%

-12.9% vs benchmark

Late-Stage Pipeline

5%

4 trials in Phase 3/4

Results Transparency

82%

23 of 28 completed with results

Key Signals

23 with results74% success

Data Visualizations

Phase Distribution

69Total
Not Applicable (4)
Early P 1 (1)
P 1 (19)
P 2 (41)
P 3 (4)

Trial Status

Completed28
Recruiting20
Terminated10
Unknown8
Active Not Recruiting7
Withdrawn4

Trial Success Rate

73.7%

Benchmark: 86.5%

Based on 28 completed trials

Clinical Trials (79)

Showing 20 of 20 trials
NCT04554914Phase 2Active Not Recruiting

A Study to Evaluate Tabelecleucel in Participants With Epstein Barr Virus (EBV) Associated Diseases

NCT07633756Phase 1Recruiting

A Phase 1b, Open-Label Study Of REC-617, A Selective CDK7 Inhibitor, In Patients With Metastatic Or Unresectable RB1-Negative Leiomyosarcoma After Prior Systemic Therapy

NCT07628634Early Phase 1Recruiting

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

NCT06975293Phase 1Recruiting

STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas

NCT02923778Phase 2Active Not RecruitingPrimary

Talimogene Laherparepvec and Radiation Therapy in Treating Patients With Newly Diagnosed Soft Tissue Sarcoma That Can Be Removed by Surgery

NCT04624178Phase 2Active Not RecruitingPrimary

A Study of Rucaparib and Nivolumab in People With Leiomyosarcoma

NCT04925089RecruitingPrimary

Localized Leiomyosarcoma Biomarker Protocol

NCT05653388RecruitingPrimary

Metastatic Leiomyosarcoma Biomarker Protocol

NCT06088290Phase 3Active Not RecruitingPrimary

Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as First-line Treatment in Participants With Metastatic Leiomyosarcoma (SaLuDo)

NCT02180867Phase 2Completed

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

NCT06789172Phase 1Recruiting

A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors

NCT07516925Phase 2RecruitingPrimary

A Study of Ivonescimab in People With Leiomyosarcoma

NCT04031677Phase 3Recruiting

Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

NCT06638931Phase 2Recruiting

Agnostic Therapy in Rare Solid Tumors

NCT04420975Phase 1Active Not RecruitingPrimary

Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma

NCT03016819Phase 3Recruiting

Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS)

NCT06308419Phase 1RecruitingPrimary

A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions

NCT04055220Not ApplicableRecruiting

Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas

NCT03851614Phase 2Active Not Recruiting

Study of DNA Damage, Angiogenesis, and PD-L1 Inhibitors in Advanced Solid Tumors

NCT07169344Phase 2Recruiting

Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue Sarcoma

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