Key Insights

Highlights

Success Rate

50% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

11.1%

2 terminated out of 18 trials

Success Rate

50.0%

-36.5% vs benchmark

Late-Stage Pipeline

6%

1 trials in Phase 3/4

Results Transparency

150%

3 of 2 completed with results

Key Signals

3 with results50% success

Data Visualizations

Phase Distribution

15Total
Not Applicable (2)
Early P 1 (2)
P 2 (10)
P 3 (1)

Trial Status

Recruiting8
Not Yet Recruiting2
Terminated2
Completed2
Unknown2
Withdrawn1

Trial Success Rate

50.0%

Benchmark: 86.5%

Based on 2 completed trials

Clinical Trials (18)

Showing 18 of 18 trials
NCT06980038Phase 2Recruiting

Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

NCT02734537Phase 2Recruiting

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

NCT04030455Phase 2Active Not RecruitingPrimary

Cisplatin, Docetaxel, and Pembrolizumab in Treating Patients With Stage II-III Laryngeal Cancer

NCT05551117Phase 2Terminated

A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors

NCT07392580Phase 2Not Yet RecruitingPrimary

Intralesional Chemotherapy (IC): Cisplatin + Epinephrine

NCT03258554Phase 2Completed

Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin

NCT06532279Phase 2Recruiting

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

NCT05333523Phase 3RecruitingPrimary

Personalized Elective Neck Irradiation Guided by Sentinel Lymph Node Biopsy in Larynx and Pharynx Cancer. The PRIMO Study.

NCT06914999Early Phase 1Recruiting

Comparing an Investigational Scan (F-18 NaF PET/CT) to Standard of Care Imaging (F-18 FDG PET/CT) for Evaluating Vascular Complications in Patients Receiving Radiation Therapy for Head and Neck Cancer

NCT07058805Phase 2Not Yet Recruiting

Compartmentalized Postoperative Radiotherapy in Head and Neck Cancer

NCT06662058Not ApplicableRecruiting

Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation

NCT06805071RecruitingPrimary

Decisional Regret in Open Partial Horizontal Laryngectomy

NCT06137378Phase 2Recruiting

European Larynx Organ Preservation Study (ELOS) [MK-3475-C44]

NCT06084845Phase 2Withdrawn

Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer

NCT05832593UnknownPrimary

Immunohistochemical Expression of Excision Repair Cross Complementation Group 1 (ERCC1) in Laryngeal Squamous Cell Carcinoma and Its Correlation With Response to Radiotherapy.

NCT02582008Early Phase 1Terminated

Bupropion Hydrochloride or Patient's Choice for Smoking Cessation in Patients With Squamous Cell Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy

NCT05293327UnknownPrimary

IMP3 and PCNA Expression in Laryngeal Squamous Cell Carcinoma in Sohag Governorate

NCT01314755Not ApplicableCompleted

A Trial of Perioperative Immune Enhancing Feed in Patients Undergoing Surgery for Head and Neck Cancer

Showing all 18 trials

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