Key Insights

Highlights

Success Rate

98% trial completion (above average)

Published Results

28 trials with published results (44%)

Research Maturity

55 completed trials (87% of total)

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 17/100

Termination Rate

1.6%

1 terminated out of 63 trials

Success Rate

98.2%

+11.7% vs benchmark

Late-Stage Pipeline

35%

22 trials in Phase 3/4

Results Transparency

51%

28 of 55 completed with results

Key Signals

28 with results98% success

Data Visualizations

Phase Distribution

58Total
Not Applicable (15)
P 1 (3)
P 2 (18)
P 3 (14)
P 4 (8)

Trial Status

Completed55
Withdrawn3
Unknown3
Not Yet Recruiting1
Terminated1

Trial Success Rate

98.2%

Benchmark: 86.5%

Based on 55 completed trials

Clinical Trials (63)

Showing 20 of 20 trials
NCT07422259Not ApplicableCompletedPrimary

Tolerability and Efficacy Study of Reinnerva/Lubristil+G vs Vismed

NCT03953703Phase 2Completed

Levocarnitine for Dry Eye in Sjogren's Syndrome

NCT07078955Phase 2Not Yet Recruiting

A Dose Regimen Study of BRM421 Ophthalmic Solution in Patients With Dry Eye Disease

NCT05918406Phase 4Completed

Phase 4 Study Evaluating the Safety of the Nasal Guide With Tyrvaya

NCT00411827Not ApplicableCompletedPrimary

Goblet Cell Response and Dry Eye Symptoms After PRK and LASIK

NCT04421300Not ApplicableCompleted

A Randomized Study of Smile Exercise for Dry Eye

NCT04649177Not ApplicableCompleted

Pilot Study to Investigate the Feasibility, Reliability and Efficacy of Utilizing OCT to Automate PROSE Fitting

NCT05618730Phase 1Unknown

Safety, Tolerability, Plug Retention and Preliminary Efficacy of Tacrolimus-loaded Punctal Plug in Patients With Moderate to Severe Dry Eye Disease - Cohort B

NCT03925727Phase 3CompletedPrimary

Tavilermide Ophthalmic Solution for the Treatment of Dry Eye

NCT04493658CompletedPrimary

Differential Diagnosis of Sjögren's Versus Non-Sjögren's Dry Eye

NCT02254265Phase 2CompletedPrimary

Phase 2/3 Dose-Ranging Study of the Safety and Efficacy of OTX-101 in the Treatment of Keratoconjunctivitis Sicca

NCT02688556Phase 3CompletedPrimary

Phase 3 Study of OTX-101 in the Treatment of Keratoconjunctivitis Sicca

NCT01235234Phase 3CompletedPrimary

Trial of CF101 to Treat Patients With Dry Eye Disease

NCT00349466Phase 2CompletedPrimary

Safety and Efficacy Study of CF101 to Treat Keratoconjunctivitis Sicca

NCT03753893Completed

Ocular Manifestations in Rheumatic Diseases

NCT04147650Phase 2Completed

Dose Ranging Study to Assess the Efficacy and Safety of Voclosporin Ophthalmic Solution in Subjects With Dry Eye Syndrome

NCT02845674Phase 3CompletedPrimary

An Open-Label Extension of a Phase 3 Study of OTX-101 in the Treatment of Keratoconjunctivitis Sicca

NCT02970799Not ApplicableCompleted

Tear Production by Nasal Neurostimulation Compared to Active Control

NCT01421498Phase 3CompletedPrimary

Safety and Efficacy Study of SAR 1118 to Treat Dry Eye Conducted in a Controlled Adverse Environment (CAE) (OPUS-1)

NCT04884217Phase 2Unknown

Treatment of Dry Eye Disease Using Pro-ocular™ - A Proof of Concept, Safety, and Efficacy Study

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