Key Insights

Highlights

Success Rate

92% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

5.1%

2 terminated out of 39 trials

Success Rate

92.0%

+5.5% vs benchmark

Late-Stage Pipeline

5%

2 trials in Phase 3/4

Results Transparency

9%

2 of 23 completed with results

Key Signals

2 with results92% success

Data Visualizations

Phase Distribution

34Total
Not Applicable (28)
P 2 (4)
P 3 (1)
P 4 (1)

Trial Status

Completed23
Recruiting5
Not Yet Recruiting3
Unknown3
Terminated2
Withdrawn2

Trial Success Rate

92.0%

Benchmark: 86.5%

Based on 23 completed trials

Clinical Trials (39)

Showing 20 of 20 trials
NCT07560618Phase 4Not Yet RecruitingPrimary

Obtaining Descriptive Classifications of Pruritus and Assessing Change in Pruritus Over Time in Atopic Dermatitis Patients Using Topical Roflumilast Cream.

NCT07247695Not ApplicableRecruitingPrimary

Mechanisms Underlying the Placebo Effect in Both Histaminergic and Non-histaminergic Itch

NCT07255092Not ApplicableNot Yet RecruitingPrimary

Mechanisms Underlying the Nocibo Effect of Contagious Itch. in Both Histaminergic and Nonhistaminergic Itch

NCT07122973Not ApplicableRecruiting

Topographical Distribution of Itch and Pain Receptors

NCT06997926Not ApplicableActive Not RecruitingPrimary

Identification of the Mechanism of Non-histaminergic Itch Inducing Epigenetic Changes

NCT06503510Not ApplicableRecruitingPrimary

Role of Interleukin-13 Pathways on Pain and Itch Sensitivity

NCT06787794Not ApplicableRecruitingPrimary

Reducing Itch With Hypnosis and Virtual Reality

NCT06245564Not ApplicableCompletedPrimary

Effect of Ketamine, Amitriptyline and Their Combination on Itch

NCT03928093Phase 3Completed

Pregabalin Treatment for RDEB Pain and Itch

NCT03943407Not ApplicableWithdrawnPrimary

Characterization of the Toll-like Receptor 7-agonist Imiquimod 3.75% As a New Surrogate Model of Itch

NCT06470737Not ApplicableCompletedPrimary

Investigation of Corticospinal Excitability Aspects of Itch and Pain

NCT06503523Not ApplicableRecruitingPrimary

The Effects of Performing a Motor Imagery Task on Cortical Excitability During Acute Experimental Muscle Pain and Acute Itch

NCT05460598Not ApplicableCompletedPrimary

The Effect of Cooling With a Bed Topper and Linen on Itch in Clinical Routine

NCT06201715Not ApplicableUnknown

Efficacy and Safety of Tofacitinib in Patients With Prurigo Nodularis

NCT05024851Terminated

Psychogenic and Neurogenic Components in Patients With Psychogenic or Neuropathic Pruritus

NCT05249387Not ApplicableCompletedPrimary

Characterization of Bovine Adrenal Medulla as a New Surrogate Model of Non-histaminergic Itch

NCT06036589Not ApplicableCompletedPrimary

Characterization of Bovine Adrenal Medulla as a Model of Non-histaminergic Itch

NCT05195177Not ApplicableUnknownPrimary

Testing Protocol to Efficiently Induce Itch

NCT05678309Not Yet Recruiting

Establishment of a Patient Library in Patients With Pruritus Sine Materia

NCT04858360Not ApplicableCompletedPrimary

Inhibition of Non-histaminergic Pruritus Applied Using 3 Different Pruritogens

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