Infection, Human Immunodeficiency Virus
116
1
2
103
Key Insights
Highlights
Success Rate
94% trial completion (above average)
Published Results
37 trials with published results (32%)
Research Maturity
103 completed trials (89% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 40/100
6.0%
7 terminated out of 116 trials
93.6%
+7.1% vs benchmark
16%
19 trials in Phase 3/4
36%
37 of 103 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 103 completed trials
Clinical Trials (116)
Study Evaluating the Efficacy, Safety, and Tolerability of Switching to Long-acting Cabotegravir Plus Long-acting Rilpivirine From Current Antiretroviral Regimen in Virologically Suppressed HIV-1-infected Adults
Phase Ib/IIa Clinical Study of ACC017 Tablets
A Phase IIb Study to Evaluate a Long-Acting Intramuscular Regimen for Maintenance of Virologic Suppression (Following Induction With an Oral Regimen of GSK1265744 and Abacavir/Lamivudine) in Human Immunodeficiency Virus Type 1 (HIV-1) Infected, Antiretroviral Therapy-Naive Adult Subjects
A Study to Determine Safety and Efficacy of Dolutegravir/Abacavir/Lamivudine (DTG/ABC/3TC) in Human Immunodeficiency Virus (HIV)-1 Infected Antiretroviral Therapy (ART) Naïve Women (ARIA)
An Efficacy, Safety, and Tolerability Study Comparing Dolutegravir (DTG) Plus Lamivudine (3TC) With Dolutegravir Plus Tenofovir/Emtricitabine in Treatment naïve HIV Infected Participants (Gemini 2)
Study Of An Investigational Regimen Including FDA Approved HIV Drugs In HIV-Infected Pediatric Subjects
An Efficacy, Safety, and Tolerability Study Comparing Dolutegravir Plus Lamivudine With Dolutegravir Plus Tenofovir/Emtricitabine in Treatment naïve HIV Infected Subjects (Gemini 1)
ING200336, Pharmacokinetic and Safety Study in Pregnant Women With Human Immuno Virus Infection
A Study of GSK1349572 Versus Raltegravir (RAL) With Investigator Selected Background Regimen in Antiretroviral-Experienced, Integrase Inhibitor-Naive Adults
GSK3640254 First Time in Human (FTIH) Study in Healthy Volunteers
GSK1265744 (Cabotegravir, CAB) for Named Patient/Compassionate Use in HIV
Open-label Study of Dolutegravir (DTG) or Efavirenz (EFV) for Human Immunodeficiency Virus (HIV) - Tuberculosis (TB) Co-infection
A Two-part Study to Compare a Tablet and Capsule Formulation of GSK2838232 With and Without Food, and to Assess the Safety and Drug Levels of Repeated Once-daily Doses of GSK2838232 Without Ritonavir
Long-term Immunogenicity of the HIV gp120-NefTat/AS01B Vaccine (GSK SB732461)
Dolutegravir Expanded Access Study
Effect of Rifabutin on the Pharmacokinetics of Oral Cabotegravir in Healthy Subjects
Pharmacokinetics Study of GSK1265744 in Subjects With Severe Renal Impairment
Pharmacokinetic Study of Cabotegravir Long-acting in Healthy Adult Volunteers
A Study to Assess Relative Bioavailability and Food Effect of New Formulations of GSK2248761
Incidence of Human Immunodeficiency Virus-1 (HIV-1) Infection in HIV-1 Uninfected High Risk Men Who Have Sex With Men