Key Insights

Highlights

Success Rate

70% trial completion

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 17/100

Termination Rate

10.0%

3 terminated out of 30 trials

Success Rate

70.0%

-16.5% vs benchmark

Late-Stage Pipeline

30%

9 trials in Phase 3/4

Results Transparency

114%

8 of 7 completed with results

Key Signals

8 with results70% success

Data Visualizations

Phase Distribution

27Total
Not Applicable (1)
P 1 (3)
P 2 (14)
P 3 (8)
P 4 (1)

Trial Status

Active Not Recruiting8
Recruiting7
Completed7
Terminated3
Not Yet Recruiting2
Enrolling By Invitation1

Trial Success Rate

70.0%

Benchmark: 86.5%

Based on 7 completed trials

Clinical Trials (30)

Showing 20 of 20 trials
NCT05248659Phase 2Enrolling By InvitationPrimary

Trial of Sibeprenlimab in the Treatment of Immunoglobulin A Nephropathy (IgAN)

NCT03719443Phase 1CompletedPrimary

First in Human Study to Assess Safety of VIS649 in Healthy Subjects

NCT06797518Phase 2Recruiting

Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgAN

NCT04287985Phase 2CompletedPrimary

Safety and Efficacy Study of VIS649 for IgA Nephropathy

NCT03762850Phase 3Active Not RecruitingPrimary

A Study of the Effect and Safety of Sparsentan in the Treatment of Patients With IgA Nephropathy

NCT06291376Phase 3RecruitingPrimary

Study of Ravulizumab in Immunoglobulin A Nephropathy (IgAN)

NCT07375758Phase 1RecruitingPrimary

A Study of MIL116 in Healthy Participants and Patients With IgA Nephropathy.

NCT07498335Phase 3Not Yet Recruiting

Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Atrasentan in Pediatric Patients With Primary IgAN

NCT05852938Phase 3Active Not Recruiting

A Study of Zigakibart in Adults With IgA Nephropathy

NCT07024563Phase 3Recruiting

Study of Ravulizumab in Pediatric Participants With Primary IgAN

NCT05248646Phase 3Active Not RecruitingPrimary

Trial of Sibeprenlimab in the Treatment of A Nephropathy (IgAN)

NCT05834738Phase 2Completed

Randomized, Double-blind, Placebo-controlled, Crossover Study of Atrasentan in Subjects With IgA Nephropathy

NCT04564339Phase 2Terminated

Study of Ravulizumab in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)

NCT05003986Phase 2Recruiting

Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

NCT06564142Phase 3Active Not RecruitingPrimary

Evaluation of Efficacy of Povetacicept in Adults With Immunoglobulin A Nephropathy (IgAN)

NCT05856760Phase 2CompletedPrimary

A Study to Investigate Safety and Effect of Sparsentan in Combination With SGLT2 Inhibition in Participants With IgAN

NCT05097989Phase 2Terminated

Study of ALXN2050 in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)

NCT05732402Phase 1Active Not Recruiting

An Open-label Study of Povetacicept in Autoantibody-Associated Glomerular Diseases

NCT04573920Phase 2Active Not Recruiting

Atrasentan in Patients With Proteinuric Glomerular Diseases

NCT06952426RecruitingPrimary

A Mobile App-Based Study to Evaluate Disease Burden and Treatment Patterns in Immunoglobulin A Nephropathy (IgAN) in the US

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