Key Insights

Highlights

Success Rate

83% trial completion

Published Results

13 trials with published results (12%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 42/100

Termination Rate

8.1%

9 terminated out of 111 trials

Success Rate

83.0%

-3.5% vs benchmark

Late-Stage Pipeline

33%

37 trials in Phase 3/4

Results Transparency

30%

13 of 44 completed with results

Key Signals

13 with results83% success

Data Visualizations

Phase Distribution

91Total
Not Applicable (16)
Early P 1 (1)
P 1 (10)
P 2 (27)
P 3 (18)
P 4 (19)

Trial Status

Completed44
Unknown18
Recruiting15
Not Yet Recruiting12
Terminated9
Active Not Recruiting7

Trial Success Rate

83.0%

Benchmark: 86.5%

Based on 44 completed trials

Clinical Trials (111)

Showing 20 of 20 trials
NCT03719443Phase 1Completed

First in Human Study to Assess Safety of VIS649 in Healthy Subjects

NCT05083364Phase 1Completed

Study of ARO-C3 in Adult Healthy Volunteers and Patients With Complement Mediated Renal Disease

NCT07541287Phase 2Not Yet RecruitingPrimary

A Phase 2 Study of JADE101 in Participants With Immunoglobulin A Nephropathy

NCT03945318Phase 1Active Not RecruitingPrimary

Safety and Tolerability of BION-1301 in Healthy Volunteers and Adults With IgA Nephropathy (IgAN)

NCT06454110Phase 2Not Yet RecruitingPrimary

Study of NM8074 in Patients With Immunoglobulin A Nephropathy (IgAN)

NCT02954419RecruitingPrimary

IgA Nephropathy Biomarkers Evaluation Study (INTEREST)

NCT05852938Phase 3Active Not RecruitingPrimary

A Study of Zigakibart in Adults With IgA Nephropathy

NCT07498335Phase 3Not Yet Recruiting

Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Atrasentan in Pediatric Patients With Primary IgAN

NCT06209177Phase 1Active Not RecruitingPrimary

Study of ARO-CFB in Adult Healthy Volunteers

NCT07481084Not Yet RecruitingPrimary

IgA Nephropathy Insights From Treatment Experience Among Patients Receiving Iptacopan and/or Atrasentan Using Primary Data Collection

NCT05016323Phase 2CompletedPrimary

A Study to Evaluate the Efficacy and Safety of HR19042 Capsules in the Treatment of Primary IgA Nephropathy.

NCT07054684Phase 1RecruitingPrimary

Study of BHV-1400 in IgA Nephropathy

NCT06712407Phase 4RecruitingPrimary

Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With Primary IgA Nephropathy

NCT05834738Phase 2CompletedPrimary

Randomized, Double-blind, Placebo-controlled, Crossover Study of Atrasentan in Subjects With IgA Nephropathy

NCT07319585UnknownPrimary

Managed Access Programs for EXV811, Atrasentan

NCT04578834Phase 3CompletedPrimary

Study of Efficacy and Safety of LNP023 in Primary IgA Nephropathy Patients

NCT03608033Phase 3TerminatedPrimary

Study of the Safety and Efficacy of OMS721 in Patients With Immunoglobulin A (IgA) Nephropathy

NCT03188887Phase 3CompletedPrimary

Treatment of IgA Nephropathy According to Renal Lesions

NCT04716231Phase 3Active Not RecruitingPrimary

Atacicept in Subjects With IgA Nephropathy

NCT06830395Phase 2Not Yet RecruitingPrimary

Study of CM313 in Subject With IgA Nephropathy

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Research Network

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