Key Insights

Highlights

Success Rate

84% trial completion

Published Results

14 trials with published results (12%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 42/100

Termination Rate

8.0%

9 terminated out of 113 trials

Success Rate

84.5%

-2.1% vs benchmark

Late-Stage Pipeline

34%

38 trials in Phase 3/4

Results Transparency

29%

14 of 49 completed with results

Key Signals

14 with results84% success

Data Visualizations

Phase Distribution

93Total
Not Applicable (16)
Early P 1 (1)
P 1 (10)
P 2 (28)
P 3 (19)
P 4 (19)

Trial Status

Completed49
Unknown18
Recruiting17
Not Yet Recruiting10
Terminated9
Active Not Recruiting5

Trial Success Rate

84.5%

Benchmark: 86.5%

Based on 49 completed trials

Clinical Trials (113)

Showing 20 of 20 trials
NCT05834738Phase 2CompletedPrimary

Randomized, Double-blind, Placebo-controlled, Crossover Study of Atrasentan in Subjects With IgA Nephropathy

NCT07498335Phase 3Recruiting

Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Atrasentan in Pediatric Patients With Primary IgAN

NCT06419205Phase 2Not Yet RecruitingPrimary

A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G

NCT05434325CompletedPrimary

TESTING -ON Post-Trial ObservatioNal Cohort Study

NCT07541287Phase 2RecruitingPrimary

A Study of JADE101 in Participants With Immunoglobulin A Nephropathy

NCT07010250Recruiting

Epithelial Dysmetabolism and Renal Fibrosis in ANCA Vasculitis

NCT07054684Phase 1RecruitingPrimary

Study of BHV-1400 in IgA Nephropathy

NCT03945318Phase 1CompletedPrimary

Safety and Tolerability of BION-1301 in Healthy Volunteers and Adults With IgA Nephropathy (IgAN)

NCT07642050Phase 3Not Yet RecruitingPrimary

A Study to Determine if BHV-1400 is Effective and Safe in Adults With IgA Nephropathy

NCT07634744Phase 2CompletedPrimary

A Phase IIa Study in Primary IgA Nephropathy Patients

NCT04573478Phase 3Active Not RecruitingPrimary

Atrasentan in Patients With IgA Nephropathy

NCT06767592Not ApplicableCompletedPrimary

A Study of Probiotics in IgA Nephropathy

NCT06350630Phase 2RecruitingPrimary

Therapeutic Effect of Hydroxychloroquine on Immunoglobulin A (IgA) Nephropathy Course QUIgAN Study

NCT04573920Phase 2Active Not RecruitingPrimary

Atrasentan in Patients With Proteinuric Glomerular Diseases

NCT05083364Phase 1Completed

Study of ARO-C3 in Adult Healthy Volunteers and Patients With Complement Mediated Renal Disease

NCT06209177Phase 1CompletedPrimary

Study of ARO-CFB in Adult Healthy Volunteers

NCT03719443Phase 1Completed

First in Human Study to Assess Safety of VIS649 in Healthy Subjects

NCT06454110Phase 2Not Yet RecruitingPrimary

Study of NM8074 in Patients With Immunoglobulin A Nephropathy (IgAN)

NCT02954419RecruitingPrimary

IgA Nephropathy Biomarkers Evaluation Study (INTEREST)

NCT05852938Phase 3Active Not RecruitingPrimary

A Study of Zigakibart in Adults With IgA Nephropathy

Scroll to load more

Research Network

Activity Timeline