Key Insights

Highlights

Success Rate

85% trial completion

Published Results

15 trials with published results (13%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 42/100

Termination Rate

7.6%

9 terminated out of 118 trials

Success Rate

84.7%

-1.8% vs benchmark

Late-Stage Pipeline

33%

39 trials in Phase 3/4

Results Transparency

30%

15 of 50 completed with results

Key Signals

15 with results85% success

Data Visualizations

Phase Distribution

96Total
Not Applicable (16)
Early P 1 (2)
P 1 (10)
P 2 (29)
P 3 (20)
P 4 (19)

Trial Status

Completed50
Unknown18
Recruiting18
Not Yet Recruiting11
Terminated9
Active Not Recruiting7

Trial Success Rate

84.7%

Benchmark: 86.6%

Based on 50 completed trials

Clinical Trials (118)

Showing 20 of 20 trials
NCT04716231Phase 3Active Not RecruitingPrimary

Atacicept in Subjects With IgA Nephropathy

NCT06419205Phase 2RecruitingPrimary

A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G

NCT07541287Phase 2RecruitingPrimary

A Study of JADE101 in Participants With Immunoglobulin A Nephropathy

NCT07634744Phase 2CompletedPrimary

A Phase IIa Study in Primary IgA Nephropathy Patients

NCT06712407Phase 4Active Not RecruitingPrimary

Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With Primary IgA Nephropathy

NCT07498335Phase 3Recruiting

Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Atrasentan in Pediatric Patients With Primary IgAN

NCT03001947RecruitingPrimary

IgA Nephropathy Registration Initiative of High Quality (INSIGHT)

NCT05190848RecruitingPrimary

Correlation of Microbiome and Metabonomics With IgA Nephropathy

NCT07785128Phase 2Not Yet RecruitingPrimary

Efficacy and Safety of Mycophenolate Mofetil in Refractory IgA Nephropathy

NCT04858724RecruitingPrimary

The Chinese Registry of Prognostic Study of IgA Nephropathy (CRPIGA)

NCT07770815Phase 3Not Yet RecruitingPrimary

Trial of Sibeprenlimab in Children and Adolescents With Immunoglobulin A Nephropathy (IgAN)

NCT07757048CompletedPrimary

A Study of Treatment Patterns and Real-World Outcomes in IgA Nephropathy Patients in the United States

NCT07754019Active Not RecruitingPrimary

Serum and Urinary sCD163 in IgA Nephropathy

NCT07203404Early Phase 1Recruiting

A Study of Anti-CD19/BCMA Universal CAR-T Cell Therapy RD06-05 in Patients With Autoimmune Diseases.

NCT05834738Phase 2CompletedPrimary

Randomized, Double-blind, Placebo-controlled, Crossover Study of Atrasentan in Subjects With IgA Nephropathy

NCT05434325CompletedPrimary

TESTING -ON Post-Trial ObservatioNal Cohort Study

NCT07010250Recruiting

Epithelial Dysmetabolism and Renal Fibrosis in ANCA Vasculitis

NCT07054684Phase 1RecruitingPrimary

Study of BHV-1400 in IgA Nephropathy

NCT03945318Phase 1CompletedPrimary

Safety and Tolerability of BION-1301 in Healthy Volunteers and Adults With IgA Nephropathy (IgAN)

NCT07642050Phase 3Not Yet RecruitingPrimary

A Study to Determine if BHV-1400 is Effective and Safe in Adults With IgA Nephropathy

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