Key Insights

Highlights

Success Rate

82% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

12.8%

6 terminated out of 47 trials

Success Rate

82.4%

-4.2% vs benchmark

Late-Stage Pipeline

2%

1 trials in Phase 3/4

Results Transparency

36%

10 of 28 completed with results

Key Signals

10 with results82% success

Data Visualizations

Phase Distribution

31Total
Not Applicable (13)
P 1 (11)
P 2 (6)
P 3 (1)

Trial Status

Completed28
Terminated6
Withdrawn3
Recruiting3
Unknown3
Active Not Recruiting2

Trial Success Rate

82.4%

Benchmark: 86.5%

Based on 28 completed trials

Clinical Trials (47)

Showing 20 of 20 trials
NCT06342999Not ApplicableEnrolling By InvitationPrimary

Fetal Aortic Valvuloplasty for Evolving Hypoplastic Left Heart Syndrome

NCT06711666Recruiting

Prenatal Maternal Mental Health and Neurodevelopment in Congenital Heart Disease

NCT03406884Phase 1CompletedPrimary

The CHILD Trial: Hypoplastic Left Heart Syndrome Study.

NCT02781922Phase 3RecruitingPrimary

Cardiac Stem/Progenitor Cell Infusion in Univentricular Physiology (APOLLON Trial)

NCT03779711Phase 2Active Not RecruitingPrimary

Intramyocardial Injection of Autologous Umbilical Cord Blood Derived Mononuclear Cells During Surgical Repair of Hypoplastic Left Heart Syndrome

NCT04925024Phase 2Active Not RecruitingPrimary

Evaluation of Lomecel-B™ Injection in Patients With Hypoplastic Left Heart Syndrome (HLHS): A Phase IIb Clinical Trial.

NCT05386173Recruiting

Effect of Fetal Aortic Valvuloplasty on Outcomes

NCT06461676Phase 1Not Yet RecruitingPrimary

Study of Intramyocardial Injection of Ventrix Bio Extracellular Matrix (VentriGel) to Assess the Safety and Feasibility in Pediatric Patients with Hypoplastic Left Heart Syndrome (HLHS)

NCT02919956CompletedPrimary

Cerebral Anatomy, Hemodynamics and Metabolism

NCT05709275TerminatedPrimary

Hypoplastic Left Heart Syndrome: Subendocardial Viability After Norwood Palliation

NCT04452188Not ApplicableCompletedPrimary

Targeting Normoxia in Neonates With Cyanotic Congenital Heart Disease in the Intra-operative and Immediate Post-operative Period

NCT01445041Phase 1TerminatedPrimary

Safety and Feasibility Study of Umbilical Cord Blood Cells for Infants With Hypoplastic Left Heart Syndrome

NCT03136835Phase 1CompletedPrimary

Maternal Hyperoxygenation in Congenital Heart Disease

NCT04181255Phase 1Terminated

Cold Heart Study: A Randomized Pilot Trial of Surfactant Therapy

NCT03079401Phase 1UnknownPrimary

Mesoblast Stem Cell Therapy for Patients With Single Ventricle and Borderline Left Ventricle

NCT01736956Not ApplicableCompleted

Fetal Intervention for Aortic Stenosis and Evolving Hypoplastic Left Heart Syndrome

NCT04581668Not ApplicableUnknown

Impact of NAVA Ventilation on Brain Oxygenation and Perfusion in Children With Congenital Heart Disease

NCT04056416Not ApplicableCompleted

Physical Activity Promotion in Children and Adolescents With Single Ventricle Physiology (MedBike)

NCT03431480Phase 1CompletedPrimary

Safety of Autologous Cord Blood Cells in HLHS Patients During Norwood Heart Surgery

NCT01883076Phase 1CompletedPrimary

Safety Study of Autologous Umbilical Cord Blood Cells for Treatment of Hypoplastic Left Heart Syndrome

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