Hypercholesterolemia, Familial
28
3
5
18
Key Insights
Highlights
Success Rate
86% trial completion
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 52/100
10.7%
3 terminated out of 28 trials
85.7%
-0.8% vs benchmark
29%
8 trials in Phase 3/4
28%
5 of 18 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 18 completed trials
Clinical Trials (28)
A Real-World Study of Long-Term Adherence and Persistence to Inclisiran, Evolocumab, and Alirocumab
Screening for Familial Hypercholesterolemia in Children
Prospective German Very High Cardiovascular Risk Patients Dyslipidemia Treatment Indication Registry
Genetic Testing and Motivational Counseling for FH
Clinical Decision Support for Familial Hypercholesterolemia
Investigational Drug in Patients With Hypercholesterolemia or in Patients With Sitosterolemia (0653-026)(COMPLETED)
PET Imaging of Inflammation and Lipid Lowering Study
Diet Quality and Coronary Artery Calcification in Adults With Heterozygous Familial Hypercholesterolemia
Expression of Pro- and Anti-inflammatory Cytokines During Anti-PCSK9 in Familial Hypercholesterolemia
Evaluating the Efficacy of Pediatric Lipid Screening Alerts
Reduction of Low-Density Lipoprotein Cholesterol (LDL-C) With PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder Study
Comparison of the Plasma Lipoprotein Apheresis Systems DIAMED and MONET vs. the Whole Blood Apheresis System DALI
Regeneron 1331 Kinetics Sub-Study HoFH
Subclinical Atherosclerosis in Patients With Familial Hypercholesterolemia Treated With Evolocumab®
Is Family Screening Improved by Genetic Testing of Familial Hypercholesterolemia
Screening Protocol for a Gene Therapy Trial in Subjects With Homozygous Familial Hypercholesterolemia
Study to Assess the Tolerability and Efficacy of Anacetrapib (MK-0859) Co-Administered With Statin in Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-020)
Study of ISIS 301012 (Mipomersen) in Heterozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy
Dose-escalating Safety Study of ISIS 301012 in Homozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy
Hyperapo B and Coronary Heart Disease