Key Insights

Highlights

Success Rate

92% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

3.2%

1 terminated out of 31 trials

Success Rate

91.7%

+5.2% vs benchmark

Late-Stage Pipeline

10%

3 trials in Phase 3/4

Results Transparency

18%

2 of 11 completed with results

Key Signals

2 with results92% success

Data Visualizations

Phase Distribution

29Total
Not Applicable (4)
Early P 1 (1)
P 1 (5)
P 2 (16)
P 3 (3)

Trial Status

Completed11
Recruiting9
Unknown6
Active Not Recruiting3
Not Yet Recruiting1
Terminated1

Trial Success Rate

91.7%

Benchmark: 86.5%

Based on 11 completed trials

Clinical Trials (31)

Showing 20 of 20 trials
NCT01042379Phase 2Recruiting

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

NCT05982093Phase 2Recruiting

Elacestrant With/Without Triptorelin in Premenopausal Women With Luminal Breast Cancer

NCT07524322Phase 1Recruiting

Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors

NCT07218432Not ApplicableRecruiting

A Study of the TheraBionic P1 Device in Breast Cancer

NCT06982521Phase 3Recruiting

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

NCT05735080Phase 1Recruiting

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

NCT06650423Recruiting

Adherence to Aromatase Inhibitors ± Abemaciclib Treatment in Patients With Early-stage HER2-negative Breast Cancer

NCT07227831Not ApplicableNot Yet Recruiting

A Ph II Study of the TheraBionic P1 Device in Subjects With Hormone Positive Breast Cancer

NCT05582499Phase 2Recruiting

Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy

NCT03904173Active Not Recruiting

Establishment of Molecular Profiling for Individual Clinical Routine Treatment Decision in Early Breast Cancer

NCT04352777Phase 2Completed

Impact of Endocrine Therapy and Abemaciclib on Host and Tumor Immune Cell Repertoire/Function in Advanced ER+/HER2- Breast Cancer

NCT05759949Phase 1Completed

First-in-Human Study of RLY-5836 in Advanced Breast Cancer and Other Solid Tumors

NCT03407768Not ApplicableCompleted

Role of Individualized Intervention(s) in Hormone-Receptor Positive Early-stage Breast Cancer

NCT03409198Phase 2Completed

Phase IIb Study Evaluating Immunogenic Chemotherapy Combined with Ipilimumab and Nivolumab in Breast Cancer

NCT05594095Phase 2Recruiting

SNF Platform Study of HR+/ HER2-advanced Breast Cancer

NCT04134884Phase 1Completed

Study of ASTX727 Plus Talazoparib in Patients With Triple Negative or Hormone Resistant/HER2-negative Metastatic Breast Cancer

NCT02730923Phase 1Unknown

Hormone Receptor Positive endometrIal Carcinoma Treated by Dual mTORC1/mTORC2 Inhibitor and Anastrozole (VICTORIA)

NCT03906669Phase 2Unknown

A Window of Opportunity Study of Pre-operative Endocrine Therapy With and Without Prometrium in Postmenopausal Women With Early Stage Breast Hormone Receptor Positive (HR+) Human Epidermal Receptor 2 Negative (HER2-) Breast Cancer.

NCT03809988Phase 2Completed

PALbociclib Rechallenge in horMone Receptor-posItive/HER2- Negative Advanced Breast Cancer (PALMIRA)

NCT03917082Phase 2Active Not Recruiting

Limited Adjuvant Endocrine Therapy for Low Risk Breast Cancer

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