Key Insights

Highlights

Success Rate

57% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

13.0%

3 terminated out of 23 trials

Success Rate

57.1%

-29.4% vs benchmark

Late-Stage Pipeline

9%

2 trials in Phase 3/4

Results Transparency

75%

3 of 4 completed with results

Key Signals

3 with results57% success

Data Visualizations

Phase Distribution

20Total
Not Applicable (2)
Early P 1 (1)
P 1 (7)
P 2 (8)
P 3 (1)
P 4 (1)

Trial Status

Recruiting7
Active Not Recruiting5
Completed4
Terminated3
Unknown2
Not Yet Recruiting1

Trial Success Rate

57.1%

Benchmark: 86.5%

Based on 4 completed trials

Clinical Trials (23)

Showing 20 of 20 trials
NCT04316117Phase 2Active Not Recruiting

Using FDG-PET/CT to Assess Response of Bone-Dominant Metastatic Breast Cancer, FEATURE Study

NCT04305834Phase 2Recruiting

Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer.

NCT06224673Phase 2Not Yet Recruiting

ARX788 for Treating Patients With HER2-low Locally Advanced Unresectable or Metastatic Breast Cancer

NCT06120283Phase 1Recruiting

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

NCT06486883Phase 2Recruiting

Safety and Efficacy of T-DXd vs. CDK4/6i-based ET as First-line Therapy of HR-positive and HER2-low/Ultralow Advanced Breast Cancer Patients Classified as Non-luminal Subtype

NCT07042581Phase 4Recruiting

A Study of Revaree Plus in People With Breast Cancer

NCT04762979Phase 2Active Not RecruitingPrimary

Alpelisib (BYL719) in Combination With Continued Endocrine Therapy Following Progression on Endocrine Therapy in Hormone Receptor Positive, HER2 Negative, PIK3CA Mutant Metastatic Breast Cancer

NCT04553770Phase 2Recruiting

Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer

NCT05565417Phase 1Active Not Recruiting

Study of the Monoclonal Antibody IMT-009 in Patients With Advanced Solid Tumors or Lymphomas

NCT04379570Phase 3Active Not Recruiting

Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy

NCT04505826Phase 1CompletedPrimary

A Dose Escalation/Expansion Study of Oral OP-1250 in Subjects With Advanced and/or Metastatic HR+, HER2- Breast Cancer

NCT05327608Not ApplicableRecruiting

Neoadjuvant Breast Cancer Time Restricted Eating

NCT05173103Completed

Retrospective Study of 2nd-line Therapies After CDK4/6i + Hormonal Therapy in HR+/HER2- Advanced Breast Cancer

NCT06805812Recruiting

Predicting clinicAL outcoMes During First-line CDK4/6 Inhibitors Plus Endocrine Therapy in Patients With Advanced Hormone REceptor-poSitive HER2-negative Breast Cancer: the Retrospective-prospective Multicenter Italian PALMARES-2 Study

NCT03845166Phase 1Active Not Recruiting

A Study of XL092 as Single-Agent and Combination Therapy in Subjects With Solid Tumors

NCT03251378Phase 1Completed

A Multi-Center, Open-Label Study of Fruquintinib in Solid Tumors and Colorectal, and Breast Cancers

NCT04726332Phase 1Terminated

Study of XL102 as Single-Agent and Combination Therapy in Subjects With Solid Tumors (QUARTZ-101)

NCT04720664Phase 2Terminated

Oral SM-88 in Patients With Metastatic HR+/HER2- Breast Cancer

NCT04305236Phase 2Terminated

Neo-Adjuvant Abemaciclib With Fulvestrant in Patients With ER/PR +HER Negative Breast Cancer

NCT05870813Unknown

CLEAR-B: Cancer Landscape - Early Adjuvant Retrospective Registry - Breast Cancer

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