Key Insights

Highlights

Success Rate

40% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 85/100

Termination Rate

15.0%

3 terminated out of 20 trials

Success Rate

40.0%

-46.5% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

0%

0 of 2 completed with results

Key Signals

40% success

Data Visualizations

Phase Distribution

15Total
P 1 (5)
P 2 (10)

Trial Status

Unknown5
Recruiting5
Terminated3
Completed2
Withdrawn2
Active Not Recruiting2

Trial Success Rate

40.0%

Benchmark: 86.5%

Based on 2 completed trials

Clinical Trials (20)

Showing 20 of 20 trials
NCT07565155Phase 2Not Yet Recruiting

Lorigerlimab (MGD019) in Patients With Pancreatic Adenocarcinoma and Homologous Recombination Deficiency

NCT03522064Phase 2Recruiting

Bipolar Androgen Therapy + Carboplatin in mCRPC

NCT06545942Phase 1Active Not Recruiting

Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

NCT04174716Phase 1Completed

Basket Trial of IDX-1197, a PARP Inhibitor, in Patients With HRR Mutated Solid Tumors (VASTUS)

NCT04780945Phase 2Terminated

Functional Analysis of BRCAness

NCT07303218Active Not Recruiting

The HER Project: HRD in EGFR-mutated NSCLC

NCT06527690Phase 2Withdrawn

Race Impact on Efficacy of Niraparib Plus Abiraterone Acetate and Prednisone in Patients With Homologous Repair Deficient Castration-resistant Prostate Cancer

NCT06095141Phase 2Recruiting

Cisplatin to Patients With Pancreatic Cancer and Homologous Recombination Deficiency

NCT03442556Phase 2Terminated

Docetaxel, Carboplatin, and Rucaparib Camsylate in Treating Patients With Metastatic Castration Resistant Prostate Cancer With Homologous Recombination DNA Repair Deficiency

NCT04515836Phase 2Recruiting

Olaparib in Patients With HRD Malignant Mesothelioma

NCT04503265Phase 1Recruiting

A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

NCT06525298Phase 1Recruiting

EIS-12656 as Single Agent and in Combination in Patients With Specified Solid Tumors

NCT03209401Phase 1Terminated

Niraparib Plus Carboplatin in Patients With Homologous Recombination Deficient Advanced Solid Tumor Malignancies

NCT05461690Phase 2UnknownPrimary

Phase II Study of Niraparib in Metastatic TNBC Patients With Homologous Recombination Deficiency

NCT05310370Unknown

HRD and Resistance to PAPPi in EOC Patients

NCT04651920Completed

A Study on Association Between HR Genes and the HRD Status in Chinese Epithelial Ovarian Cancer

NCT04651933Unknown

A Training Set for the HRD Model in EOC

NCT04556071Phase 2Unknown

Efficacy and Safety of Niraparib Combined With Bevacizumab in Platinum Refractory/Resistant Recurrent Ovarian Cancer

NCT04190667Unknown

Homologous Recombination Deficiency Status in Epithelial Ovarian Cancer

NCT03432676Phase 2Withdrawn

Epacadostat and Pembrolizumab in Treating Participants With Advanced Pancreatic Cancer

Showing all 20 trials

Research Network

Activity Timeline