Key Insights

Highlights

Success Rate

83% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

4.5%

4 terminated out of 88 trials

Success Rate

83.3%

-3.2% vs benchmark

Late-Stage Pipeline

6%

5 trials in Phase 3/4

Results Transparency

35%

7 of 20 completed with results

Key Signals

7 with results83% success

Data Visualizations

Phase Distribution

76Total
Not Applicable (4)
Early P 1 (5)
P 1 (32)
P 2 (30)
P 3 (5)

Trial Status

Recruiting36
Completed20
Unknown11
Active Not Recruiting9
Not Yet Recruiting6
Terminated4

Trial Success Rate

83.3%

Benchmark: 86.5%

Based on 20 completed trials

Clinical Trials (88)

Showing 20 of 20 trials
NCT07040072Phase 1RecruitingPrimary

Finotonlimab Combined With Stapokibart in the Treatment of Recurrent/Metastatic HNSCC

NCT04114136Phase 2Recruiting

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

NCT06190275Not ApplicableRecruitingPrimary

Clinical Study of GT201 in Combination With PD-1 Inhibitor for Advanced Head and Neck Tumors

NCT03625323Phase 2Completed

Combination Study With Soluble LAG-3 Fusion Protein Eftilagimod Alpha (IMP321) and Pembrolizumab in Patients With Previously Untreated Unresectable or Metastatic NSCLC, or Recurrent PD-X Refractory NSCLC or With Recurrent or Metastatic HNSCC

NCT07085091Phase 1Recruiting

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

NCT05581004Phase 1Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

NCT05980000Phase 2Active Not Recruiting

Ramucirumab and Pembrolizumab vs Pembrolizumab Monotherapy in PD-L1 Positive Head and Neck Squamous-Cell Carcinoma

NCT04722523Phase 1Recruiting

A Study of Cemiplimab With Chemotherapy and Immunotherapy in People With Head and Neck Cancer

NCT07462377Phase 1Recruiting

A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC

NCT07491783Phase 2Not Yet RecruitingPrimary

Nano-Carbon Iron Suspension Injection Combined With Radiotherapy for Solid Tumors Phase II Clinical Trial

NCT04042935Phase 1CompletedPrimary

Alpha Lipoic Acid to Decrease Pain and Side Effects in Concurrent Treatment of HNSCC

NCT07035249Phase 1Recruiting

DCSZ11 in Combination With Standard Therapy in Advanced or Metastatic Solid Tumors

NCT07460765Phase 1Not Yet RecruitingPrimary

Safety and Feasibility of Nivolumab-IRDye800CW in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC)

NCT06657222Phase 1Recruiting

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

NCT06305962Early Phase 1Recruiting

177Lu-anti-PD-L1 sdAb in Metastatic Solid Tumors

NCT03480672Phase 2CompletedPrimary

Postoperative aRCH With Cisplatin Versus aRCH With Cisplatin and Pembrolizumab in Locally Advanced Head and Neck Squamous Cell Carcinoma

NCT07182149Phase 1RecruitingPrimary

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

NCT05814666Phase 2TerminatedPrimary

Activity and Safety of Danvatirsen and Pembrolizumab in HNSCC

NCT03082534Phase 2CompletedPrimary

Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma

NCT06736379Phase 1Recruiting

Intratumoral Delivery of Viral Replicon (saRNA) Particles Expressing IL-12 in Head and Neck Cancer

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