Key Insights

Highlights

Success Rate

85% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

4.2%

4 terminated out of 96 trials

Success Rate

84.6%

-2.0% vs benchmark

Late-Stage Pipeline

6%

6 trials in Phase 3/4

Results Transparency

41%

9 of 22 completed with results

Key Signals

9 with results85% success

Data Visualizations

Phase Distribution

83Total
Not Applicable (4)
Early P 1 (5)
P 1 (35)
P 2 (33)
P 3 (6)

Trial Status

Recruiting39
Completed22
Unknown11
Active Not Recruiting11
Not Yet Recruiting7
Terminated4

Trial Success Rate

84.6%

Benchmark: 86.6%

Based on 22 completed trials

Clinical Trials (96)

Showing 20 of 20 trials
NCT03726775Phase 2CompletedPrimary

Trial Evaluating the Tolerance and Safety of Durvalumab - RT Combination for Treatment in SCCHN

NCT02999087Phase 3Active Not RecruitingPrimary

Randomized Trial of Avelumab-cetuximab-radiotherapy Versus SOCs in LA SCCHN (REACH)

NCT03082534Phase 2CompletedPrimary

Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma

NCT07085091Phase 1Recruiting

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

NCT07814248Phase 1Recruiting

A Phase 1, First-in-Human (FIH), Open-Label, Dose-Escalation and Dose Expansion Study of the Peptide Drug Conjugate (PDC), TS-104, as a Monotherapy in Subjects With Select Advanced Solid Tumors

NCT06736379Phase 1Recruiting

Intratumoral Delivery of Viral Replicon (saRNA) Particles Expressing IL-12 in Head and Neck Cancer

NCT06657222Phase 1Recruiting

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

NCT07462377Phase 1Recruiting

A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC

NCT07668154Phase 2RecruitingPrimary

A Phase II Study to Evaluate the Efficacy and Safety of SKB571 in Recurrent or Metastatic HNSCC Participants

NCT06597721Phase 1Recruiting

ADCE-T02, a Tissue Factor Targeted Antibody-Drug Conjugate, in Patients With Selected Advanced Solid Tumours

NCT04997902Phase 1CompletedPrimary

Combination Trial of Tipifarnib and Alpelisib in Adult Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC)

NCT07791602Phase 2Active Not Recruiting

Induction Chemoimmunotherapy Followed by Deescalated Definitive Radiotherapy in Head and Neck Cancer

NCT06016920Phase 1Recruiting

Safety and Efficacy of VB10.16 and Pembrolizumab in Patients With Head-Neck Squamous Cell Carcinoma

NCT07778732Phase 2Not Yet RecruitingPrimary

Adebrelimab Combined With Dalpiciclib Isethionate Plus Chemotherapy for Neoadjuvant Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma

NCT07182149Phase 1RecruitingPrimary

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

NCT05859074Phase 1Recruiting

A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer

NCT04354246Phase 1Completed

COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies

NCT06673693Phase 2Active Not Recruiting

Tislelizumab Combined With SBRT for the Treatment of Head and Neck Squamous Cell Carcinoma

NCT05581004Phase 1Active Not Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

NCT06819228Phase 1RecruitingPrimary

Window Trial of Fluorescently Labeled Panitumumab (Panitumumab-IRDye800) in Head and Neck Cancer

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