Key Insights

Highlights

Success Rate

50% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

14.3%

5 terminated out of 35 trials

Success Rate

50.0%

-36.6% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

40%

2 of 5 completed with results

Key Signals

2 with results50% success

Data Visualizations

Phase Distribution

28Total
Not Applicable (4)
Early P 1 (2)
P 1 (19)
P 2 (3)

Trial Status

Recruiting9
Not Yet Recruiting7
Terminated5
Completed5
Unknown4
Active Not Recruiting4

Trial Success Rate

50.0%

Benchmark: 86.6%

Based on 5 completed trials

Clinical Trials (35)

Showing 20 of 20 trials
NCT06624371Phase 1RecruitingPrimary

Atovaquone Combined With Radiation in Children With Malignant Brain Tumors

NCT07472790Phase 1Not Yet RecruitingPrimary

A Study on the Novel Oncolytic Virus Combined With PD-1 Inhibitor in the Treatment of Recurrent High-grade Glioma

NCT06946680Phase 1Not Yet RecruitingPrimary

IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent Pediatric High-grade Glioma (pHGG) and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (ndDIPG)

NCT06724926Phase 1Active Not Recruiting

Concurrent Azeliragon With Craniospinal Irradiation

NCT07532031Not Yet RecruitingPrimary

APT-weighted and Diffusion MRI for Characterizing Tumor Infiltration in High-Grade Gliomas

NCT06482905Phase 1RecruitingPrimary

Safety and Efficacy Study of TX103 CAR-T Cell Therapy for Recurrent or Progressive Grade 4 Glioma.

NCT07480941Phase 1Recruiting

Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma

NCT05610891Phase 1Active Not RecruitingPrimary

Novel Targeted Radiotherapy in Pediatric Patients With Inoperable Relapsed or Refractory HGG

NCT07457307Phase 1Not Yet RecruitingPrimary

Integrating Biology for Safe Intensification of Glioblastoma Hypofractionated Treatment on the MR-Linac

NCT04482933Phase 2Withdrawn

HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade Glioma

NCT07389278Phase 1Not Yet Recruiting

Combination ADI-PEG 20, TMZ, and RT for Treatment of Newly Diagnosed High-grade Glioma (HGG)

NCT06829173Early Phase 1RecruitingPrimary

Concurrent XRD-0394 With Radiation Therapy for High Grade Gliomas

NCT06209567Early Phase 1Active Not RecruitingPrimary

A Study of 68Ga-PSMA-11 PET Scans in People With Brain Tumors

NCT04299191Phase 1RecruitingPrimary

Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors

NCT06002711RecruitingPrimary

Multi-Dimensional MRI Spatial Heterogeneity Analysis for Predicting Key Genes and Prognosis of High-Grade Gliomas: A Multi-Center Study

NCT06831773Not ApplicableRecruiting

Clinical Study of Carbon Ion Radiotherapy for High-grade Glioma

NCT04552756Not ApplicableTerminatedPrimary

Seizures During Radiotherapy for High-grade Gliomas

NCT06737146Phase 1Not Yet RecruitingPrimary

Study of MT027 in Patients with Recurrent or Progressive High-grade Glioma

NCT06736470Recruiting

Surgical Suction Aspirates Fluorescence Measurement

NCT05561374Phase 1Active Not RecruitingPrimary

Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients with Recurrent High-Grade Glioma

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