Key Insights

Highlights

Success Rate

82% trial completion

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 27/100

Termination Rate

8.3%

2 terminated out of 24 trials

Success Rate

81.8%

-4.7% vs benchmark

Late-Stage Pipeline

13%

3 trials in Phase 3/4

Results Transparency

89%

8 of 9 completed with results

Key Signals

8 with results82% success

Data Visualizations

Phase Distribution

19Total
Not Applicable (2)
Early P 1 (1)
P 1 (3)
P 2 (10)
P 3 (3)

Trial Status

Completed9
Active Not Recruiting5
Recruiting3
Terminated2
Unknown2
Withdrawn1

Trial Success Rate

81.8%

Benchmark: 86.5%

Based on 9 completed trials

Clinical Trials (24)

Showing 20 of 20 trials
NCT03387553Early Phase 1Completed

HER2 Directed Dendritic Cell Vaccine During Neoadjuvant Therapy of HER2+Breast Cancer

NCT02654119Phase 2CompletedPrimary

Cyclophosphamide, Paclitaxel, and Trastuzumab in Treating Stage I-II HER2/Neu Positive Breast Cancer After Surgery

NCT02945579Not ApplicableRecruiting

Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy

NCT03384914Phase 2Active Not Recruiting

Vaccine to Prevent Recurrence in Patients With HER-2 Positive Breast Cancer

NCT03368729Phase 1Active Not Recruiting

Niraparib in Combination With Trastuzumab in Metastatic HER2+ Breast Cancer

NCT02827877Phase 2Active Not RecruitingPrimary

Cu64-DOTA-trastuzumab PET and Markers Predicting Response to Neoadjuvant Trastuzumab + Pertuzum in HER2+ Breast Cancer

NCT04457596Phase 3Active Not Recruiting

T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer, the CompassHER2 RD Trial

NCT06708910RecruitingPrimary

AI-based pCR Assessment/Prediction in HER2-Positive BC Using PET/MRI

NCT04249622Phase 2Terminated

Rifaximin for the Treatment of Gastrointestinal Toxicities Related to Pertuzumab-Based Therapy in Patients With Stage I-III HER2 Positive Breast Cancer

NCT07030569Recruiting

RADIomics to Predict HER2 Status And T-DXd Efficacy in Metastatic Breast Cancer: the RADIOSPHER2 Study

NCT06868758Active Not RecruitingPrimary

Predictive Value of Tumor Vascular Normalization Scoring in HER-2 Positive Breast Cancer

NCT03715959Not ApplicableCompleted

Nipple Aspirate Fluid in Detecting Breast Cancer

NCT06821490Enrolling By Invitation

Validation of TAD in HER-2 with More Than 2 Lymph Nodes

NCT03530696Phase 2Completed

T-DM1 and Palbociclib for Metastatic HER2 Breast Cancer

NCT04120246Phase 1Suspended

Alpha-TEA and Trastuzumab for the Treatment of Refractory HER2+ Metastatic Breast Cancer

NCT03500380Phase 2Unknown

A Study of RC48-ADC Administered Intravenously to Patients With HER2-Positive Metastatic Breast Cancer With or Without Liver Metastases

NCT02673398Phase 2CompletedPrimary

Neratinib in Treating Older Patients With Stage IV HER2-Positive Breast Cancer

NCT03364348Phase 1CompletedPrimary

4-1BB Agonist Monoclonal Antibody PF-05082566 With Trastuzumab Emtansine or Trastuzumab in Treating Patients With Advanced HER2-Positive Breast Cancer

NCT04351230Phase 2Withdrawn

T-DM1 With or Without Abemaciclib for the Treatment of HER2-Positive Metastatic Breast Cancer

NCT03630809Phase 2Terminated

Immune Response and Potential Booster for Patients Who Have Received HER2-pulsed DC1

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