Key Insights

Highlights

Success Rate

80% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

5.3%

1 terminated out of 19 trials

Success Rate

80.0%

-6.5% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

0%

0 of 4 completed with results

Key Signals

80% success

Data Visualizations

Phase Distribution

18Total
Early P 1 (1)
P 1 (7)
P 2 (10)

Trial Status

Recruiting8
Completed4
Active Not Recruiting3
Unknown2
Terminated1
Not Yet Recruiting1

Trial Success Rate

80.0%

Benchmark: 86.5%

Based on 4 completed trials

Clinical Trials (19)

Showing 19 of 19 trials
NCT04620187Phase 2Recruiting

Post-op T-DM1 in HER-2+ Salivary Gland Carcinomas

NCT06178445Phase 2Active Not Recruiting

Efficacy and Safety of GemCis Plus Trastuzumab Plus Pembrolizumab in Previously Untreated HER2-positive Biliary Tract Cancer

NCT07436858Phase 1Not Yet Recruiting

Whole Body HER2 Quantification With 89Zr-Trastuzumab PET/CT to Asses Zr-trastuzumab Accumulation in HER2-mutated and HER2-overexpressing Metastatic Non-small Cell Lung Cancer

NCT06824155Early Phase 1RecruitingPrimary

HEAT Trial (HER2 Antibody Therapy With Lutetium-177)

NCT06123338Phase 2Recruiting

A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer

NCT06714617Phase 1Active Not Recruiting

Evaluate BL-M17D1 in Patients w/HER2-Expressing/Mutant Advanced or Metastatic Solid Tumors

NCT05274048Phase 1Recruiting

Neratinib and Fam-Trastuzumab Deruxtecan in Advanced Gastro-esophageal Cancer Patients

NCT06449989Recruiting

Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Colorectal Cancer

NCT05650879Phase 1Active Not Recruiting

ELVN-002 in HER2 Mutant Non-Small Cell Lung Cancer

NCT05511844Phase 1Terminated

Study of ORM-5029 in Subjects With HER2-Expressing Advanced Solid Tumors

NCT06083662Phase 2Completed

Neratinib and Trastuzumab Biosimilar in Patients with HER2 Mutated Advanced Solid Cancers

NCT06383533Phase 2Recruiting

Disitamab Vedotin Plus Cadonilimab in Patients With HER2 Mutant Advanced or Metastatic Bile Duct Adenocarcinoma

NCT05991518Phase 1RecruitingPrimary

IAH0968 in Combination With GC for the Treatment of HER2-Positive Unresectable Advanced/Metastatic Malignant Tumors

NCT05673512Phase 2RecruitingPrimary

To Evaluate IAH0968 in Combination With CAPEOX in HER2-positive Metastatic Colorectal Cancer

NCT03845270Phase 2Completed

Her2-positive Lung Cancer Treated With Dedicated Drug

NCT03602079Phase 1Completed

Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene

NCT04179656Phase 2Unknown

The Basket Study of Pyrotinib Maleate for HER2-Postive Solid Tumor

NCT02979821Phase 2CompletedPrimary

Poziotinib in Stage IV Lung Adenocarcinoma With HER2 Mutation (KASTT001)

NCT03412383Phase 2Unknown

Pyrotinib in Metastatic HER2 Non-amplified But HER2 Mutant Breast Cancer

Showing all 19 trials

Research Network

Activity Timeline