Key Insights

Highlights

Success Rate

86% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

4.3%

1 terminated out of 23 trials

Success Rate

85.7%

-0.8% vs benchmark

Late-Stage Pipeline

4%

1 trials in Phase 3/4

Results Transparency

17%

1 of 6 completed with results

Key Signals

1 with results86% success

Data Visualizations

Phase Distribution

14Total
Not Applicable (1)
Early P 1 (1)
P 1 (2)
P 2 (9)
P 4 (1)

Trial Status

Recruiting8
Completed6
Unknown3
Not Yet Recruiting2
Active Not Recruiting2
Terminated1

Trial Success Rate

85.7%

Benchmark: 86.5%

Based on 6 completed trials

Clinical Trials (23)

Showing 20 of 20 trials
NCT06253871Phase 1Recruiting

A Phase 1/1b Study of IAM1363 in HER2 Cancers

NCT07506057Phase 2Recruiting

Trastuzumab in Combination With Serplulimab and Chemotherapy for the Treatment of HER2-overexpressing Unresectable Locally Advanced or Metastatic Biliary Tract Cancer or Urothelial Carcinoma After Failure of Standard Therapy

NCT06828588Early Phase 1Not Yet Recruiting

Pilot Study of [68Ga]Ga-ABY-025 Imaging in Patients Undergoing Treatment With HER2-targeted Therapy

NCT06178445Phase 2Active Not Recruiting

Efficacy and Safety of GemCis Plus Trastuzumab Plus Pembrolizumab in Previously Untreated HER2-positive Biliary Tract Cancer

NCT07454941Enrolling By Invitation

Artificial Intelligence-assisted HER2 Expression Assessment in Urothelial Carcinoma Based on Imaging-pathology Omics

NCT07356544Recruiting

Observational, Prospective, Multi-centric Study Exploring HER2 Mutations Incidence and Therapeutic Management in aNSCLC

NCT07361562Phase 1Recruiting

A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

NCT07355764Phase 2Not Yet Recruiting

MA-CRC-II-016 SHR-1811

NCT07285941Phase 2Recruiting

Efficacy and Safety of Distamab Vedotin Combined With Carboplatin for Advanced Ovarian Cancer in the First Line Treatment

NCT06125314Completed

HER2 TREAT Study: Retrospective Study to Estimate the Prevalence of HER2-low in Unresectable and/or Metastatic Breast Cancer Patients Who Progress on Anti-Cancer Therapy Identified as HER2-Negative From Patient Medical Records in The Gulf Cooperation Council

NCT07030569Recruiting

RADIomics to Predict HER2 Status And T-DXd Efficacy in Metastatic Breast Cancer: the RADIOSPHER2 Study

NCT06762977Recruiting

A Composite Assay for HER2-positive Early-stage Breast Cancer Management

NCT05661357Phase 4Active Not RecruitingPrimary

Disitamab Vedotin Combined With Fruquintinib for mCRC With HER2 Expression

NCT01542437Phase 2Completed

Treatment With BIBW 2992, Irreversible Inhibitor of EGFR and HER-2 in Non-small Cell Lung Cancer

NCT05957757Phase 2Recruiting

RC48 Combined With Tislelizumab for Bladder Sparing Treatment in NMIBC With BCG Treatment Failure and HER2 Expression

NCT05649163UnknownPrimary

Real-world Study of HER2-overexpressed Advanced Solid Tumors After Progression of First-line Standard Therapy

NCT04249440Completed

Preoperative Systemic Therapy vs Upfront Surgery in HER2 Positive Early Breast Cancer

NCT03437837Completed

Validation of the CPS+EG, Neo-Bioscore and Modified Neo-Bioscore Staging Systems After PST of BC in China

NCT02202746Phase 2Terminated

A Study to Assess the Safety and Efficacy of the VEGFR-FGFR-PDGFR Inhibitor, Lucitanib, Given to Patients With Metastatic Breast Cancer

NCT03185988Phase 2Unknown

Anti-HER2 Therapy in Patients of HER2 Positive Metastatic Carcinoma of Digestive System

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