Key Insights

Highlights

Success Rate

82% trial completion

Published Results

30 trials with published results (47%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

14.1%

9 terminated out of 64 trials

Success Rate

82.4%

-4.2% vs benchmark

Late-Stage Pipeline

2%

1 trials in Phase 3/4

Results Transparency

71%

30 of 42 completed with results

Key Signals

30 with results82% success

Data Visualizations

Phase Distribution

61Total
Not Applicable (8)
Early P 1 (1)
P 1 (28)
P 2 (23)
P 4 (1)

Trial Status

Completed42
Terminated9
Active Not Recruiting4
Withdrawn4
Recruiting3
Unknown2

Trial Success Rate

82.4%

Benchmark: 86.5%

Based on 42 completed trials

Clinical Trials (64)

Showing 20 of 20 trials
NCT05377827Phase 1Active Not Recruiting

Dose-Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Anti-CD7 Allogeneic CAR T-Cells (WU-CART-007) in Patients With CD7+ Hematologic Malignancies

NCT05475925Phase 1Recruiting

A Study of DR-01 in Subjects With Large Granular Lymphocytic Leukemia or Cytotoxic Lymphomas

NCT07055477Phase 1Recruiting

A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL)

NCT01787409Not ApplicableActive Not Recruiting

Cholecalciferol in Improving Survival in Patients With Newly Diagnosed Cancer With Vitamin D Insufficiency

NCT02588651Phase 2Completed

A Phase II Study of Single Agent Brentuximab Vedotin in Relapsed/Refractory CD30 Low (<10%) Mature T Cell Lymphoma (TCL)

NCT03113500Phase 2Active Not Recruiting

Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With CD30-Positive Peripheral T-cell Lymphoma

NCT05978141Recruiting

A Registry for People With T-cell Lymphoma

NCT01804166Phase 4CompletedPrimary

A Research Study to Bank Samples for Future Evaluation to Identify Biomarkers That Predispose Crohn's Disease and Ulcerative Colitis Patients to Develop Hepatosplenic T-Cell Lymphoma (HSTCL)

NCT02232516Phase 2Active Not Recruiting

Romidepsin and Lenalidomide in Treating Patients With Previously Untreated Peripheral T-Cell Lymphoma

NCT02168140Phase 1Completed

CPI-613 and Bendamustine Hydrochloride in Treating Patients With Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma or Hodgkin Lymphoma

NCT01769222Phase 1Terminated

Ipilimumab and Local Radiation for Selected Solid Tumors

NCT02561273Phase 1Completed

Combination Chemotherapy & Lenalidomide in Newly Diagnosed Stage II-IV Peripheral T-cell Non-Hodgkin's Lymphoma

NCT01523223Phase 1Completed

Donor Peripheral Stem Cell Transplant in Treating Patients With Hematolymphoid Malignancies

NCT01336933Phase 2Completed

Combination Chemotherapy and Pralatrexate as First-Line Therapy in Treating Patients With Non-Hodgkin Lymphoma

NCT04639843Phase 1Withdrawn

Doxorubicin, CC-(486) (5-azacitidine), Romidepsin, and Duvelisib (hARD) for T-cell Lymphoma

NCT01261247Phase 2Completed

Panobinostat in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

NCT01805037Phase 1Terminated

Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ Lymphomas

NCT00536601Not ApplicableCompleted

High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors

NCT01678443Phase 1Terminated

Monoclonal Antibody Therapy Before Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoid Malignancies

NCT01258998Phase 2Completed

Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma

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