Key Insights

Highlights

Success Rate

92% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

2.5%

1 terminated out of 40 trials

Success Rate

91.7%

+5.2% vs benchmark

Late-Stage Pipeline

10%

4 trials in Phase 3/4

Results Transparency

36%

4 of 11 completed with results

Key Signals

4 with results92% success

Data Visualizations

Phase Distribution

29Total
Not Applicable (3)
P 1 (14)
P 2 (8)
P 3 (3)
P 4 (1)

Trial Status

Recruiting12
Completed11
Active Not Recruiting6
Unknown6
Withdrawn3
Not Yet Recruiting1

Trial Success Rate

91.7%

Benchmark: 86.5%

Based on 11 completed trials

Clinical Trials (40)

Showing 20 of 20 trials
NCT04478292Phase 3RecruitingPrimary

A Multi-institutional Study for Treatment of Children With Newly Diagnosed Hepatoblastoma Using a Modified PHITT Strategy

NCT04483778Phase 1Active Not Recruiting

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

NCT06638931Phase 2Recruiting

Agnostic Therapy in Rare Solid Tumors

NCT04308330Phase 1Recruiting

Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignancies

NCT04897321Phase 1Recruiting

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

NCT02867592Phase 2Active Not Recruiting

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

NCT07148050Phase 1Recruiting

Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells

NCT07300449Phase 2RecruitingPrimary

A Prospective Multicenter Clinical Study of SCCG Protocol and ctDNA 5hmc in Predicting the Chemotherapy Sensitivity and Monitoring the Recurrence and Metastasis of Hepatoblastoma in Children and Adolescents

NCT03533582Phase 3Active Not Recruiting

Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery

NCT03618381Phase 1Active Not Recruiting

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

NCT06521567Phase 1Active Not Recruiting

A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

NCT06198296Phase 1RecruitingPrimary

Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells

NCT04337177Phase 1Recruiting

Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors

NCT07188311Not ApplicableRecruitingPrimary

Pucotenlimab Combined With Lenvatinib and Chemotherapy in the Treatment of Advanced, Relapsed/Refractory Hepatoblastoma in Children

NCT03959800Recruiting

Molecular Basis of Pediatric Liver Cancer

NCT06541652Recruiting

A French Multicenter Observational Retrospective Study of Rare Primary Liver Cancers

NCT04634357Phase 1RecruitingPrimary

ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma

NCT06822842Not Yet Recruiting

Accurate Diagnosis and Grading of Pediatric Solid Tumors Based on Pathological Large Models

NCT03220035Phase 2Completed

Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)

NCT05302921Phase 2Completed

Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors

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