Key Insights

Highlights

Success Rate

81% trial completion

Published Results

16 trials with published results (36%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

15.9%

7 terminated out of 44 trials

Success Rate

81.1%

-5.4% vs benchmark

Late-Stage Pipeline

20%

9 trials in Phase 3/4

Results Transparency

53%

16 of 30 completed with results

Key Signals

16 with results81% success

Data Visualizations

Phase Distribution

35Total
Not Applicable (2)
P 1 (11)
P 2 (13)
P 3 (5)
P 4 (4)

Trial Status

Completed30
Terminated7
Unknown4
Withdrawn1
Active Not Recruiting1
Not Yet Recruiting1

Trial Success Rate

81.1%

Benchmark: 86.5%

Based on 30 completed trials

Clinical Trials (44)

Showing 20 of 20 trials
NCT02772003Phase 1Active Not Recruiting

DNA Vaccine Therapy in Treating Patients With Chronic Hepatitis C Virus Infection

NCT02940496Phase 2Completed

Pembrolizumab (MK-3475) in Hepatocellular Carcinoma

NCT02143401Phase 1Completed

Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid Tumors

NCT04042740Phase 2CompletedPrimary

Glecaprevir/Pibrentasvir Fixed-dose Combination Treatment for Acute Hepatitis C Virus Infection

NCT05506475Not Yet Recruiting

Evaluation of HCV Care and Treatment for HIV-HCV Co-infected Patients in Decentralised Areas in Vietnam

NCT05601518UnknownPrimary

Efficacy and Safety of Coblopasvir Hydrochloride Capsules Combined With Sofosbuvir Tablets for the Treatment of Chronic HCV Infection: A Prospective, Multi-center Real-world Study.

NCT00991289Phase 2Completed

Nitazoxanide Plus Ribavirin and Peginterferon for Therapy of Treatment Naive HCV Genotype 1 and HIV Coinfected Subjects

NCT01185028Phase 1CompletedPrimary

A Safety and Tolerability Study of Nitazoxanide in HIV-HCV Treatment Failures

NCT03601546UnknownPrimary

Feasibility of Implementing a Cohort of People Living With Hepatitis C in Vietnam

NCT02582632Phase 3CompletedPrimary

A Study to Evaluate Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir in Treatment-Naïve Hepatitis C Virus Genotype 1b-Infected Adults

NCT02247401Phase 3Completed

Coadministration of ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) With Ribavirin (RBV) in Adults With Genotype 4 (GT4) Hepatitis C Virus (HCV) in Egypt

NCT01532908Phase 2TerminatedPrimary

Open Label Study of the Efficacy and Safety of MBL-HCV1 in Combination With Oral Direct-Acting Antivirals in Patients Undergoing Liver Transplantation for Hepatitis C

NCT02105701Phase 3CompletedPrimary

Study of Efficacy and Safety of Grazoprevir (MK-5172) + Elbasvir (MK-8742) With or Without Ribavirin for Participants With Hepatitis C Genotype 1, 4, or 6 Infections Who Have Failed Prior Treatment With Pegylated Interferon + Ribavirin (MK-5172-068)

NCT01841502Phase 2TerminatedPrimary

Interaction Between Paroxetine and Telaprevir

NCT02429583Phase 4TerminatedPrimary

Effects of Persistent Innate Immune Activation on Vaccine Efficacy

NCT01803308Phase 1CompletedPrimary

A Multiple Ascending Dose Phase I Study of SB 9200 in Treatment Naïve Adults With Chronic Hepatitis C Infection

NCT02247440Phase 4CompletedPrimary

HCV-HIV Co-infected Patient Cohort in Thailand

NCT02427204CompletedPrimary

Outcomes in Liver Disease Patient With and Without HIV Co-infection-Sub Study 2: HCV Treatment: Health Related Quality

NCT02982993CompletedPrimary

Hepatitis C Infection in World Trade Center Responders

NCT02076100Phase 1CompletedPrimary

Safety, Pharmacokinetics, and Pharmacodynamics of Ruzasvir (MK-8408) in Participants With Hepatitis C Infection (MK-8408-003)

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