Hepatic Insufficiency
78
5
5
64
Key Insights
Highlights
Success Rate
94% trial completion (above average)
Published Results
20 trials with published results (26%)
Research Maturity
64 completed trials (82% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 50/100
5.1%
4 terminated out of 78 trials
94.1%
+7.6% vs benchmark
3%
2 trials in Phase 3/4
31%
20 of 64 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 64 completed trials
Clinical Trials (78)
A Study to Test How Iclepertin is Taken up in the Blood of People With and Without Liver Problems
A Study of Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers.
A Study of Bomedemstat (MK-3543) in Participants With Mild or Moderate Hepatic Impairment (MK-3543-023)
A Study to Test How BI 1584862 is Taken up in the Blood of People With and Without Liver Problems
A Study Evaluating How Moderate Liver Impairment Affects the Absorption, Distribution, Metabolism, and Elimination of Sevabertinib After a Single Oral Dose
A Study of the Pharmacokinetics and Safety of Anaprazole Sodium in Special Populations
Diagnosis of Lymphohistiocytic Hemophagocytosis in Intensive Care
A Study to Evaluate CC-486/Onureg in Participants With Moderate or Severe Hepatic Impairment Compared With Normal Hepatic Function in Participants With Myeloid Malignancies
A Study of the Pharmacokinetics and Safety of LY3537031 in Participants With Normal Liver Function and With Mild, Moderate, or Severe Liver Impairment
A Study to Test How BI 1015550 is Taken up in the Blood of People With and Without Liver Problems
A Study of Imlunestrant (LY3484356) in Female Participants With Impaired Liver Function
A Study of Olomorasib (LY3537982) in Participants With Hepatic Impairment and Healthy Participants
A Clinical Study of Enlicitide Decanoate in People With Liver Function Problems (MK-0616-030)
A Study of LY3437943 in Participants With Impaired and Normal Liver Function
Hepato Biliary Scintigraphy to Assess the Risk of Postoperative Liver Failure Hepatectomies
A Study to Investigate Pharmacokinetics (PK) and Safety of a Single Dose of Mavorixafor in Participants With Hepatic Impairment (HI) Compared to Matched Healthy Volunteers With Normal Hepatic Function
Ulonivirine (MK-8507) in Participants With Mild or Moderate Hepatic Impairment (MK-8507-014)
Study to Determine the Pharmacokinetics on TPV/r in Subjects With Mild and Moderate Hepatic Insufficiency
Pharmacokinetics (PK) of Tipranavir/Ritonavir, Ribavirin, Pegylated Interferon (Peg INF) in Hepatitis C (HCV) Subjects With Mild Hepatic Impairment and in HCV, Hepatitis B (HBV), Hepatitis D Infected Subjects or Alcoholic Cirrhosis With Moderate Hepatic Impairment
Study of Pirtobrutinib (LOXO-305) in Participants With Impaired Liver Function and Healthy Participants