Key Insights

Highlights

Success Rate

71% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 39/100

Termination Rate

16.7%

5 terminated out of 30 trials

Success Rate

70.6%

-15.9% vs benchmark

Late-Stage Pipeline

40%

12 trials in Phase 3/4

Results Transparency

42%

5 of 12 completed with results

Key Signals

5 with results71% success

Data Visualizations

Phase Distribution

21Total
Early P 1 (1)
P 1 (6)
P 2 (2)
P 3 (4)
P 4 (8)

Trial Status

Completed12
Terminated5
Unknown5
Recruiting4
Active Not Recruiting3
Not Yet Recruiting1

Trial Success Rate

70.6%

Benchmark: 86.5%

Based on 12 completed trials

Clinical Trials (30)

Showing 20 of 20 trials
NCT04647227Phase 4RecruitingPrimary

SEVENFACT® for Bleeding Events in Hemophilia With Inhibitors

NCT06312475Phase 3Active Not RecruitingPrimary

Efficacy and Safety of KN057 Prophylaxis in Patients With Haemophilia A or B With Inhibitors

NCT07158606Phase 4Not Yet RecruitingPrimary

Understanding Treatment Outcomes and Immunologic Mechanisms in Altuviiio Immune Tolerance Induction

NCT04684940Phase 1Active Not RecruitingPrimary

Safety, Tolerability, and Efficacy Study of Valoctocogene Roxaparvovec in Hemophilia A With Active or Prior Inhibitors

NCT06864975Phase 4RecruitingPrimary

Assessing Different FVIII Doses and Frequencies in Immune Tolerance Induction (ITI) with ADVATE Among Hemophilia a Boys with Inhibitor (INITIATE Study)

NCT05888870Phase 4RecruitingPrimary

ITI Using SCT800 Alone or Combining Daratumumab in Hemophilia A Adolescents and Adults With High Titer Inhibitor

NCT03619863CompletedPrimary

ATHN 7: Hemophilia Natural History Study

NCT06568302Phase 3Terminated

The Long-term Safety and Efficacy of SerpinPC in Subjects with Hemophilia Who Completed a Sponsored SerpinPC Clinical Trial

NCT03951103CompletedPrimary

rFVIIIFc (Elocta®) ITI Chart Review in Patients With Haemophilia A

NCT04723693CompletedPrimary

An Exploration of the Impact of Emicizumab on the Lives of People With Haemophilia and Inhibitors and Their Families

NCT06010953Phase 1Completed

SS109 and NovoSeven ® PK / PD Profile, and Preliminary Efficacy and Safety of SS109 on Demand Treatment

NCT06357572CompletedPrimary

Real-life Clinical FEIBA Samples Measured Using the Version A of the HemA EnzySystem

NCT06320626Phase 4RecruitingPrimary

Pharmacokinetic-guided Dosing of Emicizumab

NCT05651061Phase 1CompletedPrimary

A Phase I of SS109 in Hemophilia A or and B With Inhibitors

NCT04303572Phase 3TerminatedPrimary

The Hemophilia Inhibitor Eradication Trial

NCT03818529Completed

ATHN 8: Previously Untreated Patients (PUPs) Matter Study

NCT04789954Early Phase 1CompletedPrimary

Study on the Dose-response Relationship of Pharmacodynamic Parameters in Patients With Hemophilia With Inhibitors

NCT04205175Phase 4Active Not RecruitingPrimary

A Study to Evaluate the Safest Dose Range for FEIBA in Hemophilia A Patients With Inhibitors on Emicizumab

NCT03372993CompletedPrimary

Prospective, Non-interventional Study to Evaluate Immunogenicity of AryoSeven

NCT04548791Phase 1Terminated

Study of Coagulation Factor VIIa Marzeptacog Alfa (Activated) in Subjects With Inherited Bleeding Disorders

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