Key Insights

Highlights

Success Rate

75% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

12.0%

3 terminated out of 25 trials

Success Rate

75.0%

-11.5% vs benchmark

Late-Stage Pipeline

4%

1 trials in Phase 3/4

Results Transparency

44%

4 of 9 completed with results

Key Signals

4 with results75% success

Data Visualizations

Phase Distribution

18Total
Not Applicable (2)
Early P 1 (3)
P 1 (4)
P 2 (8)
P 3 (1)

Trial Status

Completed9
Recruiting5
Withdrawn3
Terminated3
Unknown2
Suspended1

Trial Success Rate

75.0%

Benchmark: 86.5%

Based on 9 completed trials

Clinical Trials (25)

Showing 20 of 20 trials
NCT03154996Phase 1CompletedPrimary

Chronic Convection Enhanced Delivery of Topotecan

NCT07542158Phase 2Enrolling By Invitation

Ultralow Dose PET Imaging of 18F-FDOPA

NCT03952598Phase 2Suspended

Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy

NCT07374692Not ApplicableRecruiting

Observational Study of Responses to Treatments in Advanced Central Nervous System (CNS) Tumors

NCT05804227Early Phase 1RecruitingPrimary

Window-of-Opportunity Trial of Ulixertinib for MAPK-Activated Gliomas

NCT07342699CompletedPrimary

Location-Molecular Integrated Outcomes in 450 Cerebellar Glioma Microsurgical Cases

NCT03557359Phase 2CompletedPrimary

Nivolumab for Recurrent or Progressive IDH Mutant Gliomas

NCT07198256RecruitingPrimary

AI-assisted Diagnosis of Malignant Brain Tumors

NCT06969352Not Yet RecruitingPrimary

A Multicentre, Retrospective-prospective Real-world Study: to Evaluate the Effectiveness and Safety of Vorasidenib in Patients With Isocitrate Dehydrogenase IDH1/2 Mutant Grade 2 Astrocytoma or Oligodendroglioma (VICTORIA Study)

NCT06828341Early Phase 1RecruitingPrimary

A Single-arm, Open, Exploratory Clinical Study of Allogeneic CAR-T Cells in the Treatment of Relapsed/Refractory Brain Gliomas With Positive CD70 Expression

NCT06736470RecruitingPrimary

Surgical Suction Aspirates Fluorescence Measurement

NCT05054400Early Phase 1Withdrawn

Study of Laser Interstitial Thermal Therapy (LITT) Treatment Response Assessment With Fluciclovine PET MR

NCT00967577Phase 1Completed

177Lu-J591 Antibody in Patients With Nonprostate Metastatic Solid Tumors

NCT01251913Terminated

A Pilot Study of Inpatient Hospice With Procurement of Brain Tumor Tissue on Expiration for Research Purposes

NCT03091270UnknownPrimary

ZOOMit-fMRI Identifies Motor Functional Cortex

NCT02332889Phase 1TerminatedPrimary

Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETs

NCT00832598Not ApplicableCompleted

[18F] FACBC and [18F] FLT PET Imaging in Central Nervous System Tumors

NCT00200161Phase 2Completed

Temozolomide & RT Followed by Dose Dense vs Temozolomide & Retinoic Acid in Pts w/Glioblastoma

NCT00589706Phase 2CompletedPrimary

A Phase II Study of Adjuvant Use of Anti-Epidermal Growth Factor Receptor EGFR-425 in High Grade Gliomas

NCT01961934Phase 2WithdrawnPrimary

C11-Sodium Acetate PET/CT Imaging Evaluation in Brain Glioma, Post Therapy Necrosis and Pseudo-progression

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