Key Insights

Highlights

Success Rate

77% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

11.5%

3 terminated out of 26 trials

Success Rate

76.9%

-9.7% vs benchmark

Late-Stage Pipeline

4%

1 trials in Phase 3/4

Results Transparency

40%

4 of 10 completed with results

Key Signals

4 with results77% success

Data Visualizations

Phase Distribution

18Total
Not Applicable (2)
Early P 1 (3)
P 1 (4)
P 2 (8)
P 3 (1)

Trial Status

Completed10
Recruiting5
Terminated3
Withdrawn3
Unknown2
Active Not Recruiting1

Trial Success Rate

76.9%

Benchmark: 86.6%

Based on 10 completed trials

Clinical Trials (26)

Showing 20 of 20 trials
NCT07374692Completed

Observational Study of Responses to Treatments in Advanced Central Nervous System (CNS) Tumors

NCT03952598Phase 2Suspended

Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy

NCT06969352Not ApplicableActive Not RecruitingPrimary

A Multicentre, Retrospective-prospective Real-world Study: to Evaluate the Effectiveness and Safety of Vorasidenib in Patients With Isocitrate Dehydrogenase IDH1/2 Mutant Grade 2 Astrocytoma or Oligodendroglioma (VICTORIA Study)

NCT05804227Early Phase 1RecruitingPrimary

Window-of-Opportunity Trial of Ulixertinib for MAPK-Activated Gliomas

NCT03557359Phase 2CompletedPrimary

Nivolumab for Recurrent or Progressive IDH Mutant Gliomas

NCT07608003Recruiting

Multicenter Prospective Study on MRI AI Model for Midline Glioma Subtyping and Prognosis:

NCT03154996Phase 1CompletedPrimary

Chronic Convection Enhanced Delivery of Topotecan

NCT07542158Phase 2Enrolling By Invitation

Ultralow Dose PET Imaging of 18F-FDOPA

NCT07342699CompletedPrimary

Location-Molecular Integrated Outcomes in 450 Cerebellar Glioma Microsurgical Cases

NCT07198256RecruitingPrimary

AI-assisted Diagnosis of Malignant Brain Tumors

NCT06828341Early Phase 1RecruitingPrimary

A Single-arm, Open, Exploratory Clinical Study of Allogeneic CAR-T Cells in the Treatment of Relapsed/Refractory Brain Gliomas With Positive CD70 Expression

NCT06736470RecruitingPrimary

Surgical Suction Aspirates Fluorescence Measurement

NCT05054400Early Phase 1Withdrawn

Study of Laser Interstitial Thermal Therapy (LITT) Treatment Response Assessment With Fluciclovine PET MR

NCT00967577Phase 1Completed

177Lu-J591 Antibody in Patients With Nonprostate Metastatic Solid Tumors

NCT01251913Terminated

A Pilot Study of Inpatient Hospice With Procurement of Brain Tumor Tissue on Expiration for Research Purposes

NCT03091270UnknownPrimary

ZOOMit-fMRI Identifies Motor Functional Cortex

NCT02332889Phase 1TerminatedPrimary

Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETs

NCT00832598Not ApplicableCompleted

[18F] FACBC and [18F] FLT PET Imaging in Central Nervous System Tumors

NCT00200161Phase 2Completed

Temozolomide & RT Followed by Dose Dense vs Temozolomide & Retinoic Acid in Pts w/Glioblastoma

NCT00589706Phase 2CompletedPrimary

A Phase II Study of Adjuvant Use of Anti-Epidermal Growth Factor Receptor EGFR-425 in High Grade Gliomas

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