Key Insights

Highlights

Success Rate

70% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

8.6%

6 terminated out of 70 trials

Success Rate

70.0%

-16.5% vs benchmark

Late-Stage Pipeline

1%

1 trials in Phase 3/4

Results Transparency

14%

2 of 14 completed with results

Key Signals

2 with results70% success

Data Visualizations

Phase Distribution

50Total
Not Applicable (16)
Early P 1 (7)
P 1 (24)
P 2 (2)
P 3 (1)

Trial Status

Recruiting20
Completed14
Unknown10
Active Not Recruiting8
Not Yet Recruiting8
Terminated6

Trial Success Rate

70.0%

Benchmark: 86.5%

Based on 14 completed trials

Clinical Trials (70)

Showing 20 of 20 trials
NCT07416188Phase 1Not Yet Recruiting

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

NCT06636162Early Phase 1RecruitingPrimary

Window of Opportunity Study of DSP-0390 in Gliomas

NCT05283109Phase 1Active Not RecruitingPrimary

ETAPA I: Peptide-based Tumor Associated Antigen Vaccine in GBM

NCT05555550Early Phase 1Recruiting

Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG

NCT04998864CompletedPrimary

Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption in GBM Patients

NCT06810544Phase 1Recruiting

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

NCT05393258Not ApplicableCompleted

Temporally-modulated Pulsed Radiation Therapy (TMPRT) After Prior EBRT for Recurrent IDH-mutant Gliomas

NCT05076513Early Phase 1Active Not Recruiting

Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma

NCT05182905Early Phase 1Active Not Recruiting

AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients

NCT06917885Phase 1Recruiting

CUE-102 in Recurrent Glioblastoma

NCT05406700Early Phase 1Active Not Recruiting

Niraparib In Recurrent IDH 1/2 Gliomas

NCT05267509Active Not RecruitingPrimary

An Integrated Radio-immunological Approach

NCT06468176Not ApplicableRecruitingPrimary

Efficacy of a Mixed Distancial Neuropsychological Rehabilitation Program in Patients With Grade 2 or 3 Diffuse Glioma

NCT05553041Early Phase 1Recruiting

18F-Fluciclovine PET-MRI in High-grade Glioma

NCT07243340Phase 1Not Yet RecruitingPrimary

A Phase I/IIa Study of C5252 in Patients With Intracranial Tumor

NCT06169280Phase 1RecruitingPrimary

Repeated Neural Stem Cell Based Virotherapy for Newly Diagnosed High Grade Glioma

NCT06038760Terminated

Prospective Evaluation of AI R&D Tool in Adult Glioma and Other Primary Brain Tumours (PEAR-GLIO)

NCT06942104Phase 1Recruiting

Imaging of Solid Tumors Using 18F-TRX

NCT06397560Not ApplicableRecruiting

PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial

NCT05226494Phase 1RecruitingPrimary

Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma

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