Key Insights

Highlights

Success Rate

67% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

9.7%

7 terminated out of 72 trials

Success Rate

66.7%

-19.9% vs benchmark

Late-Stage Pipeline

1%

1 trials in Phase 3/4

Results Transparency

14%

2 of 14 completed with results

Key Signals

2 with results67% success

Data Visualizations

Phase Distribution

52Total
Not Applicable (16)
Early P 1 (7)
P 1 (24)
P 2 (4)
P 3 (1)

Trial Status

Recruiting19
Completed14
Unknown10
Active Not Recruiting9
Not Yet Recruiting8
Terminated7

Trial Success Rate

66.7%

Benchmark: 86.6%

Based on 14 completed trials

Clinical Trials (72)

Showing 20 of 20 trials
NCT07416188Phase 1Recruiting

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

NCT07821112Phase 2Not Yet Recruiting

Phase II Elderly/Frail Pts With Newly Diagnosed or Recurrent Malignant Glioma Treated With Cesium-131 GammaTile®

NCT05555550Early Phase 1Recruiting

Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG

NCT05226494Phase 1Active Not RecruitingPrimary

Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma

NCT07243340Phase 1RecruitingPrimary

A Phase I/IIa Study of C5252 in Patients With Intracranial Tumor

NCT05406700Early Phase 1Active Not Recruiting

Niraparib In Recurrent IDH 1/2 Gliomas

NCT06942104Phase 1Recruiting

Imaging of Solid Tumors Using 18F-TRX

NCT07707973Phase 2Not Yet RecruitingPrimary

Nimotuzumab Combined With the Stupp Regimen for Postoperative Residual Glioblastoma

NCT06169280Phase 1SuspendedPrimary

Repeated Neural Stem Cell Based Virotherapy for Newly Diagnosed High Grade Glioma

NCT05695976Suspended

GRETeL: Tumor Response to Standard Radiotherapy and TMZ Patients With GBM

NCT04547777Phase 1RecruitingPrimary

Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant Glioma

NCT06397560Not ApplicableRecruiting

PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial

NCT05979064Not ApplicableRecruiting

Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM)

NCT05954858Not ApplicableRecruitingPrimary

Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma

NCT04222309Phase 1Suspended

Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM)

NCT05271240Phase 3Recruiting

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

NCT05773326Early Phase 1Terminated

Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG

NCT06636162Early Phase 1RecruitingPrimary

Window of Opportunity Study of DSP-0390 in Gliomas

NCT05283109Phase 1Active Not RecruitingPrimary

ETAPA I: Peptide-based Tumor Associated Antigen Vaccine in GBM

NCT04998864CompletedPrimary

Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption in GBM Patients

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Research Network

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