Key Insights

Highlights

Success Rate

73% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

8.8%

3 terminated out of 34 trials

Success Rate

72.7%

-13.8% vs benchmark

Late-Stage Pipeline

3%

1 trials in Phase 3/4

Results Transparency

50%

4 of 8 completed with results

Key Signals

4 with results73% success

Data Visualizations

Phase Distribution

30Total
Not Applicable (3)
Early P 1 (4)
P 1 (15)
P 2 (7)
P 3 (1)

Trial Status

Recruiting11
Completed8
Active Not Recruiting5
Terminated3
Unknown3
Enrolling By Invitation2

Trial Success Rate

72.7%

Benchmark: 86.5%

Based on 8 completed trials

Clinical Trials (34)

Showing 20 of 20 trials
NCT04968366Phase 1CompletedPrimary

Safety & Efficacy of DC Vaccine and TMZ for the Treatment of Newly-diagnosed Glioblastoma After Surgery

NCT07464925Phase 1RecruitingPrimary

A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma

NCT03170141Phase 1Enrolling By InvitationPrimary

Immunogene-modified T (IgT) Cells Against Glioblastoma Multiforme

NCT05076513Early Phase 1Active Not Recruiting

Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma

NCT05627323Phase 1Active Not RecruitingPrimary

CAR T Cells in Patients With MMP2+ Recurrent or Progressive Glioblastoma

NCT06815432Phase 1RecruitingPrimary

GPC-3 CAR T CELLS FOR Recurrent GPC-3 Positive Glioblastoma

NCT04825275Early Phase 1Terminated

Neuro-pharmacological Properties of Repurposed Posaconazole in Glioblastoma: A Phase 0 Clinical Trial

NCT06193174Phase 1Terminated

Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1)

NCT04869449Early Phase 1Terminated

Neuro-pharmacological Properties of Repurposed Ketoconazole in Glioblastomas

NCT06991101Phase 2Recruiting

Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma

NCT06613841Early Phase 1Recruiting

Multitracer [18F]Fluciclovine and 18F-FDG PET, and Advanced MRI for Metabolic Profiling of Glioblastoma

NCT07179328Phase 1Recruiting

Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy

NCT03657576Phase 1Active Not RecruitingPrimary

Trial of C134 in Patients With Recurrent GBM

NCT05685004Phase 2Active Not RecruitingPrimary

Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM)

NCT03047473Phase 2CompletedPrimary

Avelumab in Patients With Newly Diagnosed Glioblastoma Multiforme

NCT03665545Phase 1Completed

Pembrolizumab in Association With the IMA950/Poly-ICLC for Relapsing Glioblastoma

NCT04222309Phase 1Suspended

Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM)

NCT05801159CompletedPrimary

[18F]FPIA PET-CT in Glioblastoma Multiforme (GBM)

NCT04842513Phase 1CompletedPrimary

Multi Peptide Vaccination with XS15 in Addition to Standard Postoperative Radiation Therapy and Temozolomide Chemotherapy in Newly Diagnosed Glioblastoma

NCT05979064Not ApplicableRecruiting

Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM)

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